Serum hepatic biomarkers in women with obstetric cholestasis and a concurrent SARS-CoV-2 infectionArticle Published on 2022-11-012022-11-15 Journal: The journal of obstetrics and gynaecology research [Category] SARS, 바이오마커, [키워드] age alanine aminotransferase ALT Aspartate aminotransferase association AST biliar acid Biomarker Biomarkers cholestasis COVID-19 enrolled evaluate evaluated fetal greater hospital Infection liver enzyme Obstetric obstetric cholestasis outcome Patient patients patients with SARS-CoV-2 Pregnancy pregnant women Prospective Study recruited SARS-CoV-2 SARS-COV-2 infection serum significant difference transaminases transaminases. women [DOI] 10.1111/jog.15383 PMC 바로가기
A prediction model for COVID-19 liver dysfunction in patients with normal hepatic biochemical parametersArticle Published on 2022-10-192022-11-16 Journal: Life Science Alliance [Category] 유전자 메커니즘, [키워드] Accuracy ALT Analysis AST benefit biochemical parameter Biochemical parameters Biomarker clinical variable Cohort Coronavirus disease 2019 COVID-19 COVID-19 patient Critical disease exhibit exhibited high risk identify independent limitation liver dysfunction machine learning model Patient performed predict proteomic serum sample Sex therapeutic strategy [DOI] 10.26508/lsa.202201576 PMC 바로가기
Serum qAnti-HBc combined with ALT and HBsAg predicts significant hepatic inflammation in HBeAg-positive immune active patientsArticle Published on 2022-09-012023-06-12 Journal: Journal of gastroenterology and hepatology [Category] B형 간염, [키워드] ALT HBsAg Hepatitis B virus Liver inflammation qAnti-HBc. [DOI] 10.1111/jgh.15881 PMC 바로가기
Fibrosis-4 (FIB-4) Index and mortality in COVID-19 patients admitted to the emergency departmentArticle Published on 2022-09-012022-11-15 Journal: Internal and Emergency Medicine [Category] 바이오마커, [키워드] 95% CI 95% confidence interval adjusted hazard ratio ALT Analysis AST AUC cohort study coronavirus COVID-19 COVID-19 patient Cox regression cut-off Department disease Emergency Endpoint FIB-4 fibrosis Fibrosis-4 High-flow oxygen identify increased mortality index Liver damage Liver fibrosis. liver transaminase log-rank test mechanical ventilation Mortality mortality risk Patient performed predict Predictive Prognosis ROC analysis ROC Curve secondary to define were used worse prognosis [DOI] 10.1007/s11739-022-02997-9 PMC 바로가기
Effect of intensive weight-loss intervention on metabolic, ultrasound and anthropometric parameters among patients with obesity and non-alcoholic fatty liver disease: an RCTRandomized Controlled Trial Published on 2022-09-012022-10-05 Journal: European journal of clinical nutrition [Category] 임상, [키워드] ALT AST attenuation baseline BMI Completer Contact Control control arm Controlled Effect effective Efficacy exacerbated Fatty liver groups hospital India Intensive Intervention intervention arm liver enzymes measurement NAFLD normalized obesity outcomes pandemic parameter parameters participant Patient patients with obesity Randomized RCT significant decrease significantly significantly higher steatosis stiffness therapy treat analysis Treatment outcome Trial was done weight were measured [DOI] 10.1038/s41430-022-01111-8 PMC 바로가기 [Article Type] Randomized Controlled Trial
Factors Affecting the Self-Isolation Monitoring Program for COVID-19 Patients at the Universitas Indonesia HospitalArticle Published on 2022-08-242022-11-16 Journal: Journal of Environmental and Public Health [Category] SARS, 변종, [키워드] absence administration Admission ALT Analysis Antibiotics Characteristics condition conducted COVID-19 COVID-19 patient cross-sectional determine Effectiveness electronic medical records evaluate Factor hospital increase in Indonesia MONITOR monitoring observé occurred outbreak outcome outcomes pandemic Patient patients performed Program provided risk factor Self-isolation service Shortness of breath significantly Stage suggested Symptoms the patient variant was performed with COVID-19 [DOI] 10.1155/2022/2297328 PMC 바로가기
Real-World Evidence for COVID-19 Delta Variant’s Effects on the Digestive System and Protection of Inactivated Vaccines from a Medical Center in Yangzhou, China: A Retrospective Observational StudyObservational Study Published on 2022-08-192022-10-04 Journal: International journal of clinical practice [Category] SARS, 바이오마커, 변종, 임상, [키워드] addition Affect alanine aminotransferase ALT analysis of variance ANOVA AST Bilirubin biochemical center changes in Chinese Cohort Coronavirus disease 2019 COVID-19 Critical Critical disease Delta delta variant diagnosed digestive system dysfunction early stage Effect evaluate function Gastrointestinal symptom global public health IL-6 level Inactivated vaccine inactive Infection interleukin 6 (IL-6 investigated lactate dehydrogenase LDH liver dysfunction marker mild illness moderate no significant difference p value Patient prevalent Prevent promoted PROTECT protection public health reported respiratory tract retrospective serum severity Significant significant difference significantly more Sinopharm Sinovac statistically significant Symptom System three group three groups total bilirubin Treatment Vaccine variant was used [DOI] 10.1155/2022/7405448 PMC 바로가기 [Article Type] Observational Study
Viral Dynamic Surveillance in COVID-19 Patients: A Cohort StudyArticle Published on 2022-08-192022-11-15 Journal: BioMed Research International [Category] SARS, 변종, 치료기술, [키워드] 95% CI acute respiratory syndrome affected ALT Analysis AST caused CD4+ CD8+ coronavirus Coronavirus disease 2019 COVID-19 detectable dynamic feature index Infection median Patient Pneumonia polymerase chain retrospective reverse transcription risk factor SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 variant SARS-CoV-2-infected patient Viral RNA virus was performed [DOI] 10.1155/2022/1399268 PMC 바로가기
Assessment of Tocilizumab (Humanized Monoclonal Antibody) for Therapeutic Efficacy and Clinical Safety in Patients with Coronavirus Disease (COVID-19)코로나바이러스 감염증(COVID-19) 환자의 치료 효능 및 임상 안전성에 대한 토실리주맙(인간화 단클론항체) 평가Article Published on 2022-08-102022-09-12 Journal: Medicina [Category] SARS, 진단, [키워드] activated acute respiratory distress added adverse effect airways alanine aminotransferase alkaline phosphatase ALP ALT analysis Anticoagulant ARDS assessment Autoimmune Bacterial baseline C-reactive protein characterized clinical coagulation parameter Coagulopathy control group COVID-19 COVID-19 cases COVID-19 patient COVID-19 patients CRP CRS Cytokine release syndrome Cytokine storm D-dimer discharged Efficacy Endpoint expired fatality ferritin Follow-up humanized monoclonal antibody include infection rate Inflammatory inflammatory conditions inflammatory parameter inflammatory parameters INR institution institutional protocol International lactate dehydrogenase LDH Manifestations material normalized patients of COVID-19 Platelet Pneumonia presenting Prothrombin time provided Pulmonary edema raised receiving respiratory tract infection Result Safety severe COVID-19 patients severe disease significantly higher statistically significant difference survival rate syndrome Teaching the disease the patient therapeutic efficacy Tocilizumab tocilizumab. treat Treatment Treatment protocol treatment regimen was performed [DOI] 10.3390/medicina58081076 PMC 바로가기 [Article Type] Article
Pharmacogenetic variants and risk of remdesivir-associated liver enzyme elevations in Million Veteran Program participants hospitalized with COVID-19COVID-19로 입원한 백만 재향 군인 프로그램 참가자의 약물 유전적 변이 및 렘데시비르 관련 간 효소 상승 위험Article Published on 2022-08-012022-09-11 Journal: Clinical and translational science [Category] COVID19(2023년), SARS, 변종, [키워드] adjusted administration age Alanine alanine aminotransferase ALT assigned association baseline black Comorbidities components conducted coronavirus disease Coronavirus disease 2019 COVID-19 CYP2C19 drug Drug administration Elevation enzyme food Hospitalized Linear regression liver enzyme liver enzymes log-transformed Million Veteran Program multifactorial multivariable model participant Participants Patient pharmacogenetic phenotype receiving Remdesivir retrospective risk Sex stratified Treatment treatment initiation variant was performed white with COVID-19 [DOI] 10.1111/cts.13313 PMC 바로가기 [Article Type] Article