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[키워드] ACE2 receptor binding acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Adaptive immune response alum amphiphile Antibody Response Antibody responses Antigen antigen-specific T cell candidate vaccine cellular composed consequence convalescent patient coronavirus COVID-19 CpG cytokine Cytokines dose reduction Effective vaccines ENhance evaluated humoral immune response humoral immune responses Humoral immunity IgG3 immune responses immunization induce isotype isotypes lung parenchyma lymph Lymph node lymph nodes mice Modification neutralized preserved produced Protein Protein subunit vaccines Receptor binding Receptor binding domain respiratory SARS-CoV-2 SARS-CoV-2 RBD severe acute respiratory syndrome Coronavirus spike T cell T cells T helper the SARS-CoV-2 titers translation Vaccine
[DOI] 10.1126/sciadv.abe5819 PMC 바로가기 [Article Type] Research Article