The structure-based design of peptidomimetic inhibitors against SARS-CoV-2 3C like protease as Potent anti-viral drug candidate강력한 항바이러스 약물 후보로서 SARS-CoV-2 3C 유사 프로테아제에 대한 펩티도미메틱 억제제의 구조 기반 설계Article Published on 2022-08-052022-09-11 Journal: European journal of medicinal chemistry [Category] [DOI] 10.1016/j.ejmech.2022.114458 PMC 바로가기 [Article Type] Article
Design of Novel Enantiopure Dispirooxindolopyrrolidine-Piperidones as Promising Candidates toward COVID-19: Asymmetric Synthesis, Crystal Structure and In Silico StudiesCOVID-19에 대한 유망한 후보로서의 새로운 Enantiopure Dispirooxindolopyrrolidine-Piperidones의 설계: 비대칭 합성, 결정 구조 및 인실리코 연구Article Published on 2022-06-202022-09-11 Journal: Molecules [Category] [DOI] 10.3390/molecules27123945 PMC 바로가기 [Article Type] Article
Combination of QSAR, molecular docking, molecular dynamic simulation and MM-PBSA: analogues of lopinavir and favipiravir as potential drug candidates against COVID-19QSAR, 분자 도킹, 분자 동적 시뮬레이션 및 MM-PBSA의 조합: COVID-19에 대한 잠재적 약물 후보로서 로피나비르 및 파비피라비르의 유사체Article Published on 2022-05-012022-09-11 Journal: Journal of biomolecular structure & dynamics [Category] [DOI] 10.1080/07391102.2020.1850355 PMC 바로가기 [Article Type] Article
Comparative Efficacy of Tocilizumab and Baricitinib Administration in COVID-19 Treatment: A Retrospective Cohort Study코로나19 치료에서 토실리주맙과 바리시티닙 투여의 비교 효능: 후향적 코호트 연구Article Published on 2022-04-042022-09-12 Journal: Medicina [Category] [DOI] 10.3390/medicina58040513 PMC 바로가기 [Article Type] Article
Identification of potent food constituents as SARS-CoV-2 papain-like protease modulators through advanced pharmacoinformatics approaches고급 약물 정보학 접근 방식을 통한 SARS-CoV-2 파파인 유사 프로테아제 조절제로서의 강력한 식품 성분 식별Article Published on 2022-03-012022-09-11 Journal: Journal of molecular graphics & modelling [Category] [DOI] 10.1016/j.jmgm.2021.108113 PMC 바로가기 [Article Type] Article
Discovery of Novel and Highly Potent Inhibitors of SARS CoV-2 Papain-Like Protease Through Structure-Based Pharmacophore Modeling, Virtual Screening, Molecular Docking, Molecular Dynamics Simulations, and Biological EvaluationPharmacology Published on 2022-02-212022-10-31 Journal: Frontiers in Pharmacology [Category] [DOI] 10.3389/fphar.2022.817715 PMC 바로가기 [Article Type] Pharmacology
Growth, Antigenicity, and Immunogenicity of SARS-CoV-2 Spike Variants Revealed by a Live rVSV-SARS-CoV-2 VirusMedicine Published on 2022-01-072022-10-31 Journal: Frontiers in Medicine [Category] [DOI] 10.3389/fmed.2021.793437 PMC 바로가기 [Article Type] Medicine
Antiviral activity of 5-aminolevulinic acid against variants of severe acute respiratory syndrome coronavirus 2Research Published on 2022-01-072022-10-28 Journal: Tropical Medicine and Health [Category] [DOI] 10.1186/s41182-021-00397-x PMC 바로가기 [Article Type] Research
COVID-19 Transcriptomic Atlas: A Comprehensive Analysis of COVID-19 Related Transcriptomics DatasetsGenetics Published on 2021-12-222022-10-31 Journal: Frontiers in Genetics [Category] [DOI] 10.3389/fgene.2021.755222 PMC 바로가기 [Article Type] Genetics
Imiquimod Boosts Interferon Response, and Decreases ACE2 and Pro-Inflammatory Response of Human Bronchial Epithelium in AsthmaImiquimod는 인터페론 반응을 높이고 ACE2 및 천식에서 인간 기관지 상피의 염증 반응을 감소시킵니다Immunology Published on 2021-12-072022-09-11 Journal: Frontiers in Immunology [Category] [DOI] 10.3389/fimmu.2021.743890 PMC 바로가기 [Article Type] Immunology