Association between antidiabetic drug use and the risk of COVID-19 hospitalization in the INSIGHT Clinical Research Network in New York CityArticle Published on 2022-07-012023-07-08 Journal: Diabetes, obesity & metabolism [Category] COVID19(2023년), [키워드] antidiabetic drug cohort study observational study pharmacoepidemiology type 2 diabetes [DOI] 10.1111/dom.14704 PMC 바로가기
A review on protective roles and potential mechanisms of metformin in diabetic patients diagnosed with COVID-19Research article Published on 2021-12-012022-10-05 Journal: Metabolism Open [Category] 신약개발, [키워드] ACE2 activities acute respiratory syndrome Alter Anti-inflammatory antidiabetic drug antioxidant Antiviral blood glucose Cardiopulmonary caused chronic inflammation coronavirus COVID-19 COVID-19 patients COVID‐19 database detrimental effect diabetes Diabetes Mellitus diabetic patient diagnosed with COVID-19 disease severity Elsevier English globe Google Scholar gut microbiota Healthcare system immunomodulatory immunomodulatory activity include infected patients investigated maintaining mechanism medication metformin molecular mechanism novel coronavirus disease potential mechanism protective role Protein public health reduced reduction in mortality risk factor SARS‐CoV‐2 searched survival Treatment Vascular viral entry virus Web of Science with COVID-19 [DOI] 10.1016/j.metop.2021.100137 [Article Type] Research article
Dipeptidyl Peptidase-4 Inhibitors and COVID-19-Related Deaths among Patients with Type 2 Diabetes Mellitus: A Meta-Analysis of Observational Studies제2형 당뇨병 환자의 디펩티딜 펩티다제-4 억제제 및 코로나19 관련 사망: 관찰 연구의 메타 분석Meta-Analysis Published on 2021-08-012022-09-11 Journal: Endocrinology and metabolism (Seoul, Korea) [Category] 바이오마커, [키워드] Administered affected antidiabetic drug coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19-related death death decrease demonstrated diabetes Diabetes Mellitus Diabetes mellitus, type 2 dipeptidyl peptidase Dipeptidyl-peptidase IV inhibitors disease pathogenesis enzyme epicenter fatal disease implicated inhibitor Meta-analysis Mortality observational studies observational study outcome pandemic Pathogenesis Patient Randomized controlled trial risk risk of COVID-19 subjects the disease Treatment Type type 2 diabete Type 2 diabetes mellitus [DOI] 10.3803/EnM.2021.1048 PMC 바로가기 [Article Type] Meta-Analysis
‘de Novo’ repurposing of Daflon as anti-intestinal parasitic drug in experimental giardiasisResearch article Published on 2021-07-012022-10-05 Journal: Experimental Parasitology [Category] 신약개발, [키워드] Albino Analysis antidiabetic drug assigned Combined therapy control group days post-infection demonstrated develop dismutase drug Drug administration drug resistance Efficiency eight epithelial European country experimental group Frequency Giardia giardiasis histopathological in vivo indicated inoculated intestinal material MDA metronidazole mice multiple dose murine model objective oxidative stress Progressive reduced Result retained Safe significantly small intestine Stage tissue treated widespread [DOI] 10.1016/j.exppara.2021.108124 [Article Type] Research article
Diabetes and coronavirus (SARS-CoV-2): Molecular mechanism of Metformin intervention and the scientific basis of drug repurposing당뇨병 및 코로나바이러스(SARS-CoV-2): 메트포르민 개입의 분자 메커니즘 및 약물 용도 변경의 과학적 근거Review Published on 2021-06-222022-09-10 Journal: PLoS Pathogens [Category] MERS, 신약개발, 치료제, [키워드] acute respiratory syndrome coronavirus administration adverse outcomes affected Anti-inflammatory antidiabetic drug Antidiabetic drugs antioxidant Antiviral blood glucose Cardiopulmonary caused complications contribute coronavirus coronavirus 2 coronavirus disease Coronavirus disease 2019 correlated COVID-19 COVID-19 patients detrimental effect detrimental effects Diabetic disease severity Effect explain Glucose ICU admissions immunomodulatory increased risk individual individuals insulin Intervention maintaining mechanism metformin molecular mechanism molecular mechanisms Mortality mortality rate new strain new strain of coronavirus pandemic reduced reduction in respiratory SARS-CoV-2 severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 Treatment Vascular WHO [DOI] 10.1371/journal.ppat.1009634 PMC 바로가기 [Article Type] Review
The potential effects of clinical antidiabetic agents on SARS-CoV-2SARS-CoV-2에 대한 임상 항당뇨병제의 잠재적 효과Article Published on 2021-03-012022-09-11 Journal: Journal of diabetes [Category] 치료제, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus-2 antidiabetic agents antidiabetic drug approach can be used Canagliflozin caused Chinese conditions conducted coronavirus disease Coronavirus disease 2019 Coronavirus-2 COVID-19 cutoff value diabetes Diabetic docking docking score docking scores drug Drug discovery drug target Effect English glimepiride glipizide gliquidone highest identify indicated inhibitor Ligand linagliptin M pro N3 inhibitor nelfinavir notable outcome Patient pharmacophore pharmacophores predicted progression proportion protease public health repaglinide reported SARS-CoV-2 Screen Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus threat Treatment treatment of COVID-19 新型冠状病毒。 新型冠状病毒肺炎 糖尿病 降糖药物. [DOI] 10.1111/1753-0407.13135 PMC 바로가기 [Article Type] Article
Sodium-glucose co-transporter-2 inhibitors and susceptibility to COVID-19: A population-based retrospective cohort studyArticle Published on 2021-01-012023-07-06 Journal: Diabetes, obesity & metabolism [Category] SARS, [키워드] antidiabetic drug DPP-4 inhibitor pharmaco-epidemiology SGLT2 inhibitor type 2 diabetes [DOI] 10.1111/dom.14203 PMC 바로가기
Anti-inflammatory properties of antidiabetic drugs: A “promised land” in the COVID-19 era?Review article Published on 2020-12-012022-10-05 Journal: Journal of diabetes and its complications [Category] SARS, 바이오마커, [키워드] anti-inflammatory property antidiabetic drug Biomarker C-reactive protein clinically coronavirus disease COVID-19 COVID-19 pandemic COVID-19 positive patients CRP diabetes Dipeptidyl peptidase 4 inhibitors ferritin Glucagon-like peptide-1 receptor agonists glycemic control IL-6 implicated Inflammation Inflammatory marker interleukin 6 interleukin-6 metformin morbidity and mortality outcome pathophysiology patients with diabete pioglitazone predictor reduce reported risk risk factor severity Sodium-glucose co-transporter-2 inhibitors [DOI] 10.1016/j.jdiacomp.2020.107723 [Article Type] Review article
Clinical Characteristics of COVID-19 Patients with and without Diabetes in Wuhan Red Cross HospitalResearch Article Published on 2020-08-102022-10-29 Journal: Journal of Diabetes Research [Category] COVID-19, MERS, SARS, [키워드] 95% CI Admission albumin antidiabetic antidiabetic drug Blood urea nitrogen China clinical Clinical characteristics Clinical symptoms COVID-19 COVID-19 patient COVID-19 patients D-dimer death diabete diabetes Diabetic drug fasting blood Glucose group In-hospital death independent risk factor low molecular weight Lymphocytes Mortality mortality rate multivariable analysis no difference Novel coronavirus Odds ratio Older oxygen saturation patients with diabete plasma Pneumonia Red Result risk factor SARS-CoV-2- significantly higher Spread total bilirubin two group was performed White blood cells Wuhan [DOI] 10.1155/2020/1652403 PMC 바로가기 [Article Type] Research Article
Potential Benefits and Harms of Novel Antidiabetic Drugs during COVID-19 CrisisCommunication Published on 2020-05-222022-10-29 Journal: International Journal of Environmental Research an [Category] COVID-19, MERS, SARS, [키워드] activities affecting agonist antidiabetic antidiabetic drug associations Clinical prognosis complications COVID-19 COVID-19 crisis COVID-19 infection COVID-19 pandemic crisis deficiency diabete diabetes DPP4 DPP4 inhibitors drug Evidence fatal COVID-19 GLP1 receptor agonists glycemic heterogeneity high risk immune responses infections Inflammatory cytokine inhibitor insulin intensive care unit likelihood management mechanisms modulation novel Patient Potential potential benefit Prevalence receptor reported Respiratory failure SGLT2 inhibitors susceptibility viral entry widespread [DOI] 10.3390/ijerph17103664 PMC 바로가기 [Article Type] Communication