Nasal cathelicidin is expressed in early life and is increased during mild, but not severe respiratory syncytial virus infectionArticle Published on 2024-06-172024-09-05 Journal: Scientific Reports [Category] update2024, [키워드] Acute inflammation antimicrobial peptide Antimicrobial responses Cathelicidin hCAP-18 Host defence peptide Innate immunity LL-37 Microbiome nasal respiratory respiratory syncytial virus Viral host response viral infection [DOI] 10.1038/s41598-024-64446-1 PMC 바로가기 [Article Type] Article
Studies on the in vitro mechanism and in vivo therapeutic effect of the antimicrobial peptide ACP5 against Trichophyton mentagrophytesArticle Published on 2024-05-312024-08-30 Journal: Peptides [Category] 백선증, [키워드] ACP5 antimicrobial peptide dermatophytosis Fungicidal Mechanism T. mentagrophytes. PMC 바로가기
Antimicrobial resistance crisis: could artificial intelligence be the solution?Review Published on 2024-01-232024-09-05 Journal: Mil Med Res [Category] update2024, [키워드] antibiotic antibiotic stewardship antimicrobial peptide Artificial intelligence (AI) clinical development machine learning (ML) phage therapy [DOI] 10.1186/s40779-024-00510-1 PMC 바로가기 [Article Type] Review
Inhibition of Pertussis Toxin by Human α-Defensins-1 and -5: Differential Mechanisms of Action인간 α-디펜신-1 및 -5에 의한 백일해 독소 억제: 차별적인 작용 메커니즘Article Published on 2023-06-232024-08-25 Journal: International Journal of Molecular Sciences [Category] 백일해, [키워드] antimicrobial peptide bacterial AB-type toxin Defensins human peptide mechanism of inhibition Pertussis toxin toxin inhibitor.
A review of the antiviral activity of cationic antimicrobial peptidesArticle Published on 2023-05-102024-09-05 Journal: Peptides [Category] update2024, [키워드] antimicrobial peptide Cationic antiviral peptide enveloped virus non-enveloped virus [DOI] 10.1016/j.peptides.2023.171024 PMC 바로가기 [Article Type] Article
[Progress of researches on antimalarial peptides]Article Published on 2023-04-192024-08-29 Journal: Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi [Category] 말라리아, [키워드] Antimalarial agent antimicrobial peptide malaria Plasmodium
A Comparison of Cathelicidin Levels in the Skin of Leprosy Patients and Their Household ContactsOriginal Research Study Published on 2023-01-012024-09-05 Journal: Acta medica academica [Category] update2024, [키워드] antimicrobial peptide Cathelicidin Enzyme-Linked Immunoabsorbent Assay leprosy Neutrophils [DOI] 10.5644/ama2006-124.424 PMC 바로가기 [Article Type] Original Research Study
Antimicrobial peptides: A promising tool to combat multidrug resistance in SARS CoV2 eraArticle Published on 2022-12-012022-11-15 Journal: Microbiological research [Category] COVID19(2023년), SARS, 치료제, [키워드] acute respiratory syndrome against SARS-CoV AMP AMPs antimicrobial antimicrobial agent antimicrobial peptide antimicrobial resistance Antiviral antiviral agent antiviral peptides caused Compound coronavirus coronavirus 2 COVID-19 COVID-19 pandemic drug resistance effective Effectiveness highlight highly pathogenic life-threatening mechanism microbial infections peptide respiratory SARS-CoV-2 SARS-COV-2 infection severe acute respiratory syndrome Coronavirus therapeutic drug therapeutic strategy Treatment variety viral infection virus [DOI] 10.1016/j.micres.2022.127206 PMC 바로가기
Vitamin D enhances type I IFN signaling in COVID-19 patientsArticle Published on 2022-10-222022-11-15 Journal: Scientific Reports [Category] COVID19(2023년), SARS, 치료제, [키워드] 95% confidence interval adjusted hazard ratio Admission all-cause mortality antimicrobial peptide Antiviral Antiviral effect antiviral response collected COVID-19 infection COVID-19 patient ENhance Host host response IFN in vitro intensive care interferon investigated ISGs JAK-STAT signaling pathway lower risk modulate on type outcome patient survival patients PBMC protein level Regulatory saliva specimen SARS-CoV-2 SARS-COV-2 infection severe COVID-19 patient Signaling significantly higher treated treated patient treated patients Treatment Type I IFN untreated patient Vitamin D Whole blood [DOI] 10.1038/s41598-022-22307-9 PMC 바로가기
Molecular Docking and In-Silico Analysis of Natural Biomolecules against Dengue, Ebola, Zika, SARS-CoV-2 Variants of Concern and Monkeypox VirusArticle Published on 2022-09-222022-11-15 Journal: International Journal of Molecular Sciences [Category] SARS, 변종, 진단, 치료제, [키워드] Amino acid AMP AMPs antimicrobial peptide Antiviral antiviral drug Antiviral treatment AutoDock vina B.1.617.2 Bacterial bacterial AMPs binding energy Biomolecule biomolecules Cell cell receptor cell surface receptors concern Control Dengue dengue virus determine develop docking docking score Ebola Ebola virus Effective vaccines envelope protein Evolution in silico increase in indicated Modification molecular molecular docking Monkeypox mutant natural Occurrence P.1 pathogenic viruses positive proline Protein receptors SARS-CoV-2 Secondary Metabolite specific neutralizing antibody tested the SARS-CoV-2 the spike protein therapeutic agents variant variants of SARS-CoV-2 viral cell viral surface virus was performed Zika Zika virus [DOI] 10.3390/ijms231911131 PMC 바로가기