Clinical factors affecting depression in patients with painful temporomandibular disorders during the COVID-19 pandemic Research Published on 2022-08-292022-10-05 Journal: Scientific Reports [Category] 치료법, [키워드] Affect affecting aggravate Anxiety arthralgia assessment axis BAI Beck clinical clinical factors COVID-19 COVID-19 pandemic Depression diagnosed disorder Factor Factors female females high correlation increase in intensity inventory investigated moderate multifactorial Multiple regression analysis myalgia negatively affected Novel coronavirus Pain pandemic Patient physical positively correlated Psychological Psychological distress recent Sex significantly significantly increased Stress stress level temporomandibular disorder TMD TMD pain was recorded [DOI] 10.1038/s41598-022-18745-0 [Article Type] Research
The Robustness of Cellular Immunity Determines the Fate of SARS-CoV-2 Infection세포 면역의 견고함이 SARS-CoV-2 감염의 운명을 결정합니다Review Published on 2022-06-272022-09-11 Journal: Frontiers in Immunology [Category] COVID19(2023년), SARS, 치료제, [키워드] addition Administered Analysis antibody secreting cells antiviral cytokine antiviral cytokines antiviral immunity antiviral response appearance approach autosomal recessive axis B cell booster dose breadth CD4+ CD4+ T cell CD8+ Cell cellular Cellular immune response cellular immunity component contribute coordinating correlated COVID-19 COVID-19 patient Critical cross-protection Cytokines cytotoxic lymphocytes cytotoxic T lymphocytes described disease Disease progression disease severity dysregulated evasion Evolution follicular functional Germinal center global pandemic greater helper T cells humoral IFN-γ immune protection immune system Immunity in some infected cells Infection infection control inflammatory cascade innate immune system killing knowledge long-lasting lymphocyte Lymphocytes magnitude memory modulating neutralizing antibody pathogenic inflammation phenotypic pro-inflammatory cytokine pro-inflammatory cytokines protective immunity reported responsible robustness SARS-CoV-2 SARS-CoV-2 virus secreting severe COVID-19 severity Stage stages T cell T cell response T cell responses T cells T helper cell T helper cells Tfh Tfh cells the SARS-CoV-2 virus thought TNF-α vaccination Vaccine viral replication X-linked [DOI] 10.3389/fimmu.2022.904686 PMC 바로가기 [Article Type] Review
High Seroprevalence of SARS-CoV-2 in White-Tailed Deer (Odocoileus virginianus) at One of Three Captive Cervid Facilities in Texas텍사스에 있는 세 곳의 자궁경부 사육 시설 중 하나에서 흰꼬리사슴(Odocoileus virginianus)에서 SARS-CoV-2의 높은 혈청유병률Article Published on 2022-04-272022-09-11 Journal: Microbiology Spectrum [Category] COVID19(2023년), SARS, 변종, 치료기술, [키워드] axis can not captive cervid Contact coronavirus Coverage Critical cross-sectional cross-sectional study deer endpoint titer endpoint titers epizootiology Evidence evidence of explained facilitate facilitated facility Free Health horizontal transmission Human human population Impact increasingly Infection Neutralization assay Neutralizing antibodies neutralizing antibody Odocoileus population increase PRNT Region reported reservoir SARS-CoV-2 SARS-CoV-2 RNA SARS-CoV-2 vaccine seronegative seropositive Seroprevalence spillover subset Support Swab tested the United State The United States These data Transmission transmission of SARS-CoV-2 United States variants variants of concern virus white-tailed deer zoonosis [DOI] 10.1128/spectrum.00576-22 PMC 바로가기 [Article Type] Article
Visualizing omicron: COVID-19 deaths vs. cases over time오미크론 시각화: 시간 경과에 따른 COVID-19 사망자 대 사례Article Published on 2022-04-192022-09-11 Journal: PLoS ONE [Category] COVID19(2023년), SARS, 변종, [키워드] automatically axis caused code country COVID-19 COVID-19 pandemic death deaths dominant variant feature Github GitHub repository indicated omicron Omicron variant pandemic plot progressed provided reported South Africa starting point variant [DOI] 10.1371/journal.pone.0265233 PMC 바로가기 [Article Type] Article
The Impact of Age and BMI on the VWF/ADAMTS13 Axis and Simultaneous Thrombin and Plasmin Generation in Hospitalized COVID-19 PatientsMedicine Published on 2022-01-102022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] ADAMTS13 addition age aging Analysis analyzed Antigen axis binding activity BMI body mass index Coagulation Coagulopathy collagen collected conditions contribute contributed Corona COVID-19 COVID-19 negative cross-sectional elevated endothelial Endothelial dysfunction factor VIII Generation Health hospital Impact increases in increasing age individual obesity Older parameter Patient plasma plasmin populations positive reduced risk severity Simultaneous thrombin von Willebrand factor vWF [DOI] 10.3389/fmed.2021.817305 PMC 바로가기 [Article Type] Medicine
Cardiovascular Risk After SARS-CoV-2 Infection Is Mediated by IL18/IL18R1/HIF-1 Signaling Pathway AxisSARS-CoV-2 감염 후 심혈관 위험은 IL18/IL18R1/HIF-1 신호 경로 축에 의해 매개됩니다Immunology Published on 2022-01-052022-09-11 Journal: Frontiers in Immunology [Category] 유전자 메커니즘, 치료기술, 치료제, [키워드] activate activated Activation Algorithm Analysis Aneurysm aneurysms Atherosclerosis axis cardiovascular cardiovascular risk Cell cell types changes in characterized choice Compound COVID-19 COVID-19 infection detect Epigenetic expected functional gene co-expression network HIF-1 HIF-1 signaling pathway HIF1a hypoxia identify IL-18 IL18 IL18R1 Infection Inference Intercellular communication interleukin locus Macrophage macrophages MAP2K1 mechanism Mediated MEK inhibitor Methylation NF-κB nucleus objective pathway Pathways PBMC phenotype phenotypic Potential promote promoted Proteins Proteomic analysis Regulation Regulatory Regulon Result SARS-CoV-2 SARS-COV-2 infection scRNA-seq Signaling signaling pathway smooth muscle therapeutic compound therapeutic target Treatment type I interferon type I interferon pathway vascular smooth muscle vascular smooth muscle cells VIPER was used WGCNA with COVID-19 [DOI] 10.3389/fimmu.2021.780804 PMC 바로가기 [Article Type] Immunology
IL1β Promotes TMPRSS2 Expression and SARS-CoV-2 Cell Entry Through the p38 MAPK-GATA2 AxisImmunology Published on 2021-12-072022-11-01 Journal: Frontiers in Immunology [Category] COVID-19, SARS, [키워드] ACE2 Affect axis COVID-19 effort favor GATA2 Host IL1β IL1β indicated Inflammatory Inflammatory cytokine investigated modulating molecular mechanism p38 pandemic pro-inflammatory progression regulate Research SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 pathogenesis susceptibility the disease the SARS-CoV-2 TMPRSS2 TMPRSS2 expression [DOI] 10.3389/fimmu.2021.781352 PMC 바로가기 [Article Type] Immunology
Cirrhosis-Associated RAS-Inflammation-Coagulation Axis Anomalies: Parallels to Severe COVID-19Article Published on 2021-12-012022-10-30 Journal: Journal of Personalized Medicine [Category] COVID-19, [키워드] abnormal coagulation abnormality ACE acute respiratory distress acute respiratory distress syndrome Angiotensin-converting enzyme Antigen axis C-reactive protein characterized cirrhosis coagulation parameter correlated COVID patient COVID-19 COVID-19 patients CRP D-dimer Endothelial dysfunction exhibited fibrinolysis healthy subject IL-6 Increased increased risk Inflammation interleukin-6 investigated Liver disease Mild nine parameter Patient patients patients with COVID-19 portal hypertension RAS RAS activity renin-angiotensin-system severe COVID-19 severity significantly syndrome systemic inflammation upregulation venous vWF [DOI] 10.3390/jpm11121264 PMC 바로가기 [Article Type] Article
Involvement of the ACE2/Ang-(1–7)/MasR Axis in Pulmonary Fibrosis: Implications for COVID-19Review Published on 2021-11-302022-10-29 Journal: International Journal of Molecular Sciences [Category] COVID-19, MERS, SARS, [키워드] ACE2 acute respiratory distress affecting Alter ARDS Asymptomatic axis cannabis cause cigarette smoke cigarette smoking Complication Coronavirus infection COVID-19 COVID-19 pandemic current death disease entry of SARS-CoV-2 events Evidence expression facilitate fibrosis increase Inflammation Involvement Lung disease Lung diseases mechanical ventilation pandemic Pathogenesis Prevalence pulmonary pulmonary fibrosis receptor reduce Research Respiratory failure responsible risk factor Risk factors SARS-CoV-2 severe pneumonia similarity Support susceptibility Symptom syndrome the SARS-CoV-2 virus thought virus [DOI] 10.3390/ijms222312955 PMC 바로가기 [Article Type] Review
Neuropsychiatric Ramifications of COVID-19: Short-Chain Fatty Acid Deficiency and Disturbance of Microbiota-Gut-Brain Axis SignalingReview Article Published on 2021-10-052022-10-27 Journal: BioMed Research International [Category] [키워드] accompanied ACE-2 acid alleviate Altered Anti-inflammatory anti-inflammatory function axis Bacteria binding Brain changes in characterized commensal bacteria Complication components contribute COVID-19 COVID-19 patient Critical decrease deficiency described diagnostic disorders disturbance evaluate fatty favor fecal fiber gastrointestinal symptoms Gut gut microbiota gut microbiota composition implicated increase in Inflammation metabolite microbial Neurological disorder Neuropsychiatric Pathogens Prevent producing proinflammatory Psychiatric ramification receptor recommendation Research risk SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 receptors SCFA signaling pathway supported systemic inflammation Transport turn viral presence [DOI] 10.1155/2021/7880448 PMC 바로가기 [Article Type] Review Article