Neutralizing and enhancing monoclonal antibodies in SARS-CoV-2 convalescent patients: lessons from early variant infection and impact on shaping emerging variantsNon-Neutralizing Protective Antibodies Published on 2024-01-192024-09-05 Journal: Emerging Microbes & Infections [Category] update2024, [키워드] Antibody-dependent enhancement B cell repertoire COVID-19 emerging variants Human monoclonal antibody [DOI] 10.1080/22221751.2024.2307510 PMC 바로가기 [Article Type] Non-Neutralizing Protective Antibodies
Impact of Host Immune Status on Discordant Anti-SARS-CoV-2 Circulating B Cell Frequencies and Antibody Levels불일치 항 SARS-CoV-2 순환 B 세포 주파수 및 항체 수준에 대한 숙주 면역 상태의 영향Article Published on 2021-10-142022-09-12 Journal: International Journal of Molecular Sciences [Category] MERS, SARS, 진단, [키워드] Analysis anti-SARS-CoV-2 anti-SARS-CoV-2 antibody antibody antibody synthesis Antiviral antiviral antibodies B cell B cell repertoire caution circulating clone clones Comorbidities convalescent COVID-19 determined by develop failure frequencies Frequency functional healthcare personnel hospitalized patient hospitalized patients Human monoclonal antibody immortalized immunofluorescence Impact indirect immunofluorescence individual infected cells Level low-grade inflammation Neutralizing protective immunity reflect regulate responses reveal SARS-CoV-2 SARS-CoV-2 infected cells severe COVID-19 Severe patient severe patients statistically status two group two groups [DOI] 10.3390/ijms222011095 PMC 바로가기 [Article Type] Article
Unbiased interrogation of memory B cells from convalescent COVID-19 patients reveals a broad antiviral humoral response targeting SARS-CoV-2 antigens beyond the spike proteinResearch article Published on 2021-08-012022-10-05 Journal: Vaccine: X [Category] 치료제, [키워드] Anti-viral anti-viral antibody antibody Antibody Response antigen-specific T cell Antiviral approach auxiliary B cell repertoire Cell characterized components convalescent COVID-19 patient convalescent patient convalescent plasma COVID-19 COVID-19 convalescent patient COVID-19 patient demonstrated effective expected full-length full-length protein humoral identify Immunoglobulin majority membrane memory B memory B cell monoclonal antibody nucleocapsid ORF performed produced Protein Proteins Pseudovirus neutralization assay RBD reveal S protein SARS-CoV-2 SARS-CoV-2 antigen SARS-COV-2 infection Somatic hypermutation specific antibody spike the antibody the receptor-binding domain the Spike the spike protein Viral proteins [DOI] 10.1016/j.jvacx.2021.100098 [Article Type] Research article
Next-Generation Sequencing of T and B Cell Receptor Repertoires from COVID-19 Patients Showed Signatures Associated with Severity of DiseaseArticle Published on 2020-06-302023-06-16 Journal: Immunity [Category] MERS, SARS, [키워드] B cell repertoire COVID-19 cytokine profile immunoglobulin heavy chain interferon SARS-CoV-2-specific antibody T cell compartments T cell receptor clusters T cell repertoire [DOI] 10.1016/j.immuni.2020.06.024 PMC 바로가기 [Article Type] Article
B-cell repertoire responses to varicella-zoster vaccination in human identical twinsArticle Published on 2015-01-132023-06-02 Journal: Proceedings of the National Academy of Sciences of [Category] 두창, [키워드] antibody B cell repertoire convergent twin Varicella zoster vaccine [DOI] 10.1073/pnas.1415875112 PMC 바로가기