Reciprocal regulation of lncRNA MEF and c-Myc drives colorectal cancer tumorigenesisOriginal Research Published on 2024-02-012024-09-05 Journal: Neoplasia (New York, N.Y.) [Category] update2024, [키워드] c-MYC Colorectal cancer hnRNPK lncRNA-MEF TRIM25 [DOI] 10.1016/j.neo.2024.100971 PMC 바로가기 [Article Type] Original Research
Discovery Proteomics Analysis Determines That Driver Oncogenes Suppress Antiviral Defense Pathways Through Reduction in Interferon-β Autocrine StimulationDiscovery Proteomics 분석을 통해 드라이버 종양유전자가 인터페론-β 자가분비 자극 감소를 통해 항바이러스 방어 경로를 억제한다는 사실이 확인되었습니다.Article Published on 2022-07-012022-09-11 Journal: Molecular & Cellular Proteomics : MCP [Category] COVID19(2023년), SARS, 유전자 메커니즘, 치료법, [키워드] activated AKT Antiviral approach autocrine BRAF c-MYC Cancer cancer cell line cancer cell lines cancers Cell cell line cellular DDX58 develop double-stranded double-stranded RNA downregulation driven by driving dsRNA EGFR expression functional hallmark HER2 immune evasion Infection interferon KRAS lower expression MEK molecular MYC OAS oncogene oncogenes. oncogenic osteosarcoma Pancreatic cancer phenotypic profiles Protein Proteins proteome provide reduced regulated response RIG-I RNA virus SARS-CoV-2 shown Stimulation susceptibility susceptibility to infection therapeutic treated type 1 interferon [DOI] 10.1016/j.mcpro.2022.100247 PMC 바로가기 [Article Type] Article
Clinicopathological and Immunohistochemical Profile of Mantle Cell Lymphoma: An Institutional ExperienceArticle Published on 2021-07-212023-08-30 Journal: Cureus [Category] E형 간염, [키워드] aberrant phenotype Biology c-MYC cyclin D1 mantle cell lymphoma SOX11 TP53 [DOI] 10.7759/cureus.16534 PMC 바로가기
Targeting SLC1A5 and SLC3A2/SLC7A5 as a Potential Strategy to Strengthen Anti-Tumor Immunity in the Tumor MicroenvironmentImmunology Published on 2021-04-192022-11-01 Journal: Frontiers in Immunology [Category] COVID-19, [키워드] accumulating Acidic activate addition Amino acid amino acid transporter anti-tumor immunity c-MYC Cancer caused Cell cell metabolism chimeric antigen receptor demonstrated ENhance Evidence Express expression function functions Glucose Glutamine growth hypoxic Immune cell immune cells immunometabolism Immunotherapy induce infiltration Invasion leucine limitation metabolism metabolites mTORC1 Natural killer cells nutrient transporters overcome plasma membrane Potential proliferation promote regulatory pathway required robust SLC1A5 SLC3A2 SLC7A5 Strategy subcellular subunit T cells targeting therapy transcription factor Tumor tumor microenvironment tumors [DOI] 10.3389/fimmu.2021.624324 PMC 바로가기 [Article Type] Immunology
HBx and c-MYC Cooperate to Induce URI1 Expression in HBV-Related Hepatocellular CarcinomaCommunication Published on 2019-11-142023-06-03 Journal: International Journal of Molecular Sciences [Category] B형 간염, [키워드] c-MYC E-box HBV-related hepatocellular carcinoma HBx URI1 [DOI] 10.3390/ijms20225714 PMC 바로가기 [Article Type] Communication
Chronic inflammation contributes to the development of hepatocellular carcinoma by decreasing miR-122 levelsResearch Paper Published on 2016-03-292023-06-02 Journal: Oncotarget [Category] B형 간염, [키워드] c-MYC C/EBPα IL-6 miR-122 TNF-α [DOI] 10.18632/oncotarget.7740 PMC 바로가기 [Article Type] Research Paper