Lipid nanoparticle-encapsulated DOCK11-siRNA efficiently reduces hepatitis B virus cccDNA level in infected miceOriginal Article Published on 2024-06-242024-09-05 Journal: Molecular Therapy [Category] update2024, [키워드] cccDNA DOCK11 gapmer HBV hetero gapmer LNP-siRNA nucleic acid medicine [DOI] 10.1016/j.omtm.2024.101289 PMC 바로가기 [Article Type] Original Article
Arsenic trioxide impacts hepatitis B virus core nuclear localization and efficiently interferes with HBV infectionResearch Article Published on 2024-05-032024-09-05 Journal: Microbiology Spectrum [Category] update2024, [키워드] antivirals arsenic cccDNA dsDNA viruses HBV Hepatitis B virus PML-NB SUMO [DOI] 10.1128/spectrum.03788-23 PMC 바로가기 [Article Type] Research Article
Mechanisms of Hepatitis B Virus cccDNA and Minichromosome Formation and HBV Gene TranscriptionReview Published on 2024-04-152024-09-05 Journal: Viruses [Category] update2024, [키워드] cccDNA DNA repair HBV Hepatitis B virus Viral hepatitis viral transcription [DOI] 10.3390/v16040609 PMC 바로가기 [Article Type] Review
Intrahepatic homeobox protein MSX-1 is a novel host restriction factor of hepatitis B virusarticle Published on 2024-02-162024-09-05 Journal: Journal of virology [Category] update2024, [키워드] cccDNA HBV HNF4α homeoprotein transcriptional regulation [DOI] 10.1128/jvi.01345-23 PMC 바로가기 [Article Type] article
Review of Related Factors for Persistent Risk of Hepatitis B Virus-Associated Hepatocellular CarcinomaReview Published on 2024-02-142024-09-05 Journal: Cancers [Category] update2024, [키워드] antiviral therapy cccDNA Hepatitis B virus hepatitis cure Hepatocellular carcinoma nucleoside analog [DOI] 10.3390/cancers16040777 PMC 바로가기 [Article Type] Review
Liver Carcinogenesis Suppression in Chronic Hepatitis B in the Nucleoside Analogues EraReview Article Published on 2024-01-032024-09-05 Journal: In vivo (Athens, Greece) [Category] update2024, [키워드] Carcinogenesis cccDNA hepatitis B surface antigen Hepatitis B virus Nucleos(t)ide analogue review [DOI] 10.21873/invivo.13408 PMC 바로가기 [Article Type] Review Article
Cytosine base editing inhibits hepatitis B virus replication and reduces HBsAg expression in vitro and in vivoOriginal Article Published on 2023-12-272024-09-05 Journal: Molecular Therapy. Nucleic Acids [Category] update2024, [키워드] base editing cccDNA gene editing HBsAg HBV Lipid nanoparticles MT: RNA/DNA Editing Therapeutics [DOI] 10.1016/j.omtn.2023.102112 PMC 바로가기 [Article Type] Original Article
Classifying hepatitis B therapies with insights from covalently closed circular DNA dynamicsReview Published on 2023-12-162024-09-05 Journal: Virologica Sinica [Category] update2024, [키워드] cccDNA Dynamics functional cure hepatitis B Strategy Treatment [DOI] 10.1016/j.virs.2023.12.005 PMC 바로가기 [Article Type] Review
Recent Advances in the Development of Sulfamoyl-Based Hepatitis B Virus Nucleocapsid Assembly ModulatorsReview Published on 2023-11-302024-09-05 Journal: Viruses [Category] update2024, [키워드] CAMs cccDNA HBV core protein Hepatitis B virus [DOI] 10.3390/v15122367 PMC 바로가기 [Article Type] Review
Immunoinformatics and Evaluation of Peptide Vaccines Derived from Global Hepatitis B Viral HBx and HBc Proteins Critical for Covalently Closed Circular DNA IntegrityArticle Published on 2023-11-212024-09-05 Journal: Microorganisms [Category] update2024, [키워드] cccDNA global HBV HBC HBx Peptide vaccines [DOI] 10.3390/microorganisms11122826 PMC 바로가기 [Article Type] Article