SARS-CoV-2 specific plasma cells acquire long-lived phenotypes in human bone marrowarticle Published on 2023-08-082024-09-05 Journal: eBioMedicine [Category] update2024, [키워드] CD19 CD45 human bone marrow Humoral memory long-lived plasma cell SARS-CoV-2 [DOI] 10.1016/j.ebiom.2023.104735 PMC 바로가기 [Article Type] article
Clinical and laboratory features in health care volunteers with inactivated SARS-CoV-2 vaccinationResearch Article Published on 2023-05-252024-09-05 Journal: Turkish Journal of Medical Sciences [Category] update2024, [키워드] CD19 COVID-19 healthcare IL-2 IL-6 vaccination [DOI] 10.55730/1300-0144.5684 PMC 바로가기 [Article Type] Research Article
Timing of SARS-CoV-2 Vaccination Matters in People With Multiple Sclerosis on Pulsed Anti-CD20 TreatmentArticle Published on 2022-10-122022-11-15 Journal: Neurology® neuroimmunology & neuroinflammation [Category] COVID19(2023년), SARS, 바이오마커, 변종, 진단, [키워드] acute respiratory syndrome Analysis analyzed anti-SARS-CoV-2 antibody Antibody Response association Blood CD19 CD3 CD4 CD8 CD8 T cell CD8 T-cell response cellular center clinical decision Cohort collected conducted coronavirus coronavirus disease correlated cross-sectional Defense evaluate Germany humoral immune response Humoral response immune response Immunoglobulin Infection interferon-γ interval lymphocyte counts matter Multiple multiple sclerosis Patient peptide pools receiving regulated response responses Sample SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 spike SARS-CoV-2 vaccination sclerosis significantly increased Spike protein Status post subpopulation T cell T-cell the timing Treatment vaccination vaccination response Vaccination strategy variants of concern were measured [DOI] 10.1212/NXI.0000000000200031 PMC 바로가기
Response to SARS-CoV-2 vaccines in patients receiving B-cell modulating antibodies for renal autoimmune diseaseArticle Published on 2022-09-142022-11-15 Journal: BMC Infectious Diseases [Category] SARS, 진단, [키워드] Adequate anti-CD20 anti-CD20 treatment antibody antibody treatment Autoimmune disease B-cell B-cells CD19 CD20 cellular cellular response clinical correlated COVID-19 depleting develop disease generate humoral immune Immunity immunization kidney modulating Patient patients receiving treatment receiving regimens Registered renal response retrospective rituximab SARS-CoV-2 SARS-CoV-2 vaccination SARS-CoV-2 vaccine single-center timespan Treatment vaccination vaccination response [DOI] 10.1186/s12879-022-07722-7 PMC 바로가기
Immunogenicity profiling and distinct immune response in liver transplant recipients vaccinated with SARS-CoV-2 inactivated vaccinesArticle Published on 2022-09-142022-11-15 Journal: Frontiers in Immunology [Category] SARS, 진단, [키워드] anti-RBD antibody CD19 CD19+ CD3+ CD3+ CD19+ cell CD4+ cell CD4+ T cell Cell cells cellular immunity Clinical characteristics Concentration CXCL10 DNT effector memory enrolled groups humoral immune profiling immune response immune system immunogenicity immunotype inactivated Inactivated vaccine innate immune response liver liver transplant recipient Lymphocyte count monocyte NAb National Neutralizing Neutralizing antibodies neutralizing antibody plasma Population positive proportion provided recipient recipients reported responders responses SARS-CoV-2 SARS-CoV-2 inactivated vaccines severe adverse event single-cell T-cell three groups time TNF-alpha Type vaccination vaccination schedule were recorded [DOI] 10.3389/fimmu.2022.954177 PMC 바로가기
Subcutaneous immunoglobulins in chronic lymphocytic leukemia with secondary antibody deficiency. A monocentric experience during Covid-19 pandemics2차 항체 결핍을 동반한 만성 림프구성 백혈병에서 피하 면역글로불린. Covid-19 전염병 동안의 단일 중심적 경험Article Published on 2022-08-012022-09-12 Journal: Hematological oncology [Category] MERS, 진단, [키워드] administration age antibody appear baseline CD19 CD4/CD8 chronic lymphocytic leukemia CLL Comorbidities COVID 19 deficiency dosage dose Efficacy and safety eligibility event expenditures FIVE Frequency hypogammaglobinemia IgG IgG levels immune immune dysfunction Immunoglobulin immunoglobulin replacement therapy immunoglobulins increase infections initiated interstitial pneumonia leukemia lymphocyte Pandemics Patient Prophylaxis Quality of life receiving reduced risk of infections Safe secondary secondary antibody Subcutaneous subcutaneous immunoglobulins. subset therapy treated Treatment were recorded [DOI] 10.1002/hon.2966 PMC 바로가기 [Article Type] Article
Upregulation of PD-1 Expression and High sPD-L1 Levels Associated with COVID-19 SeverityCOVID-19 심각성과 관련된 PD-1 발현 및 높은 sPD-L1 수치의 상향 조절Article Published on 2022-08-012022-09-11 Journal: Journal of Immunology Research [Category] SARS, 바이오마커, 유전자 메커니즘, [키워드] (PD-1 addition association Biomarker CD14 CD14+ monocyte CD14+ monocytes CD19 CD19+ cellular COVID-19 COVID-19 patients death Depletion evaluated Exhaustion expression Frequency increase in Infection inhibiting inhibitor lead Level lymphocyte Lymphocytes mechanism monocyte Monocytes Patient PD-1 Protein SARS-COV-2 infection SARS-CoV-2-infected patients severity TCD4 TCD8 the disease therapeutic target These cells These data with COVID-19 [DOI] 10.1155/2022/9764002 PMC 바로가기 [Article Type] Article
Defining Clinical and Immunological Predictors of Poor Immune Responses to COVID-19 mRNA Vaccines in Patients with Primary Antibody DeficiencyArticle Published on 2022-08-012022-11-15 Journal: Journal of Clinical Immunology [Category] COVID19(2023년), SARS, 진단, [키워드] anti-S IgG antibody association Autoimmunity B-cells baseline CD19 CD4 CD8 Cellular immune response clinical Cohort common common variable immune deficiency coronavirus disease Coronavirus disease 2019 correlated COVID-19 COVID-19 mRNA vaccines criteria CVID deficiency develop Diagnosis disease dose expression Frequency HCs humoral IgA IgG IgG deficiency IgG subclasse immune Immune profile immunological characteristics impairment investigated memory Moderna Moderna mRNA vaccine mRNA mRNA vaccine naïve neutralization activity OX40 Patient Pfizer-BioNTech Pfizer-BioNTech mRNA vaccine Poor predicted primary antibody primary antibody deficiency response responses SARS-CoV-2 spike protein Selective IgG subclass deficiency significantly lower Specific Specific antibody deficiency. subset T-cell T-cell Response T-cells vaccination Vaccine vaccine response [DOI] 10.1007/s10875-022-01296-4 PMC 바로가기
Infectious complications, immune reconstitution, and infection prophylaxis after CD19 chimeric antigen receptor T-cell therapy Reviews Published on 2022-07-152022-10-05 Journal: Bone marrow transplantation [Category] 치료제, [키워드] CAR CD19 Cell chimeric antigen receptor clinically complications Cytokine release syndrome disease Evidence Factor hematologic Hypogammaglobulinemia immune immune function incidence increasingly Infection less lymphoid malignancies Patient patients Prophylaxis recipient risk factor Side effect standard treatment T-cell T-cells therapy Treatment undergo Vaccination strategy [DOI] 10.1038/s41409-022-01756-w [Article Type] Reviews
Immune Cells Profiles In The Peripheral Blood Of Patients With Moderate To Severe COVID-19 And Healthy Subjects With and Without Vaccination With The Pfizer-BioNTech mRNA VaccinePfizer-BioNTech mRNA 백신 접종 여부에 관계없이 중등도에서 중증 COVID-19 환자 및 건강한 피험자의 말초혈 면역 세포 프로필Article Published on 2022-07-112022-09-11 Journal: Frontiers in Immunology [Category] COVID19(2023년), SARS, 치료기술, [키워드] acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 adaptive analyzed B cell B cells Blood causative agent caused CD14 CD16 CD19 CD19+ CD3+ CD4+ CD4+ T cells CD4+ T lymphocyte CD56 CD56+ CD8+ T cell CD8+ T cells clinical manifestations coronavirus 2 coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patient COVID-19 patients detectable determine dysregulated flow cytometry Frequency group healthy control healthy subject healthy subjects HLA-DR host response immune Immune cell immune cells immune response Inflammatory Kuwait lymphocyte Lymphocyte subset Lymphocyte subsets Lymphocytes moderate moderate to severe monocyte monocyte subsets Monocytes mRNA mRNA vaccine NK cell NK cells no symptom no symptoms percentage percentages peripheral Peripheral blood Perturbation perturbations Pfizer Pfizer-BioNTech profile profiles PROTECT required respiratory SARS-CoV-2 Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus severe disease significantly higher significantly lower subjects subset T cells T lymphocytes the patient three group three groups vaccination was performed with COVID-19 [DOI] 10.3389/fimmu.2022.851765 PMC 바로가기 [Article Type] Article