Comparative Efficacy of Tocilizumab and Baricitinib Administration in COVID-19 Treatment: A Retrospective Cohort Study코로나19 치료에서 토실리주맙과 바리시티닙 투여의 비교 효능: 후향적 코호트 연구Article Published on 2022-04-042022-09-12 Journal: Medicina [Category] 진단, [키워드] all-cause mortality analysis analyzed anti-viral drug Baricitinib baseline chronic renal disease Clinical characteristics clinically Comparative conducted coronavirus disease COVID-19 COVID-19 patient drug Drug administration early administration event exhibited hospital IMPROVE independent Infection material Most patient multivariate logistic regression outcome Patient patients hospitalized patients treated performed Prognostic factor retrospective Retrospective study secondary severity severity of COVID-19 significantly single-center study steroid survival rate TCZ the Kaplan-Meier method the log-rank test the patient Tocilizumab tocilizumab. treated Treatment university with COVID-19 [DOI] 10.3390/medicina58040513 PMC 바로가기 [Article Type] Article
An Overview of Systematic Reviews of the Role of Vitamin D on Inflammation in Patients with Diabetes and the Potentiality of Its Application on Diabetic Patients with COVID-19당뇨병 환자의 염증에 대한 비타민 D의 역할에 대한 체계적인 검토에 대한 개요 및 Covid-19를 가진 당뇨병 환자에 대한 적용의 잠재력Review Published on 2022-03-062022-08-31 Journal: International Journal of Molecular Sciences [Category] COVID-19, MERS, meta-analysis, SARS, [키워드] acute respiratory syndrome application association cardiovascular disease chronic lung disease chronic renal disease Cochrane Library Comorbidities contribute coronavirus coronavirus disease Coronavirus disease 2019 correlated COVID-19 COVID-19 patient COVID-19 severity Cytokines deficiency diabete diabetes Diabetes Mellitus Effect Evidence Factor Health care health care systems high risk hyperglycemia hypertension immune immune response immune system Immune system dysfunction in some increase increased mortality Infection Infectious disease Inflammation Inflammatory marker inflammatory markers Inflammatory responses inflammatory state Lung disease malignancy modulator molecular basis mortality rate obesity outbreak overview pandemic Patient patients patients with comorbidity performed piece potentiality PubMed Central renal disease reported respiratory review role Severe acute respiratory syndrome severity subject systematic review systematic reviews systemic inflammatory response systemic inflammatory responses Vitamin D vitamin D deficiency Vitamin D supplementation vitamin D’ vitamin D’s with COVID-19 Wuhan [DOI] 10.3390/ijms23052873 PMC 바로가기 [Article Type] Review
Association of Vitamin D receptor gene polymorphisms and clinical/severe outcomes of COVID-19 patientsResearch article Published on 2021-12-012022-10-05 Journal: Infection, genetics and evolution : journal of mol [Category] 유전자 메커니즘, [키워드] allele association Asthma Asymptomatic CDX2 chronic renal disease Clinical data clinical outcomes clinical symptom Comorbidities Comorbidity COVID-19 COVID-19 patient COVID-19 patients Critical critical impact dependent on diabete eight evaluated Evidence Fever FokI function genetic model Genetic predisposition Genotype genotyped geographical regions hypertension Infection Iran not significant outcome outcomes Patient polymerase chain polymorphism Prognosis receptor Result risk severity severity of COVID-19 Shortness of breath signaling pathway Significant Single nucleotide polymorphism Single nucleotide polymorphisms (SNPs) SNPs Symptoms VDR Vitamin D Vitamin D receptor vomiting with COVID-19 [DOI] 10.1016/j.meegid.2021.105098 [Article Type] Research article
Clinical Features and Laboratory Examination to Identify Severe Patients with COVID-19: A Systematic Review and Meta-AnalysisReview Article Published on 2021-11-152022-10-27 Journal: BioMed Research International [Category] COVID-19, MERS, [키워드] Analysis C-reactive protein cardiovascular disease Chest China Chinese chronic renal disease chronic respiratory clinical clinical factor clinical feature Comorbidities contribute cough COVID-19 COVID-19 epidemic COVID-19 patients database diagnosed Diagnosis diarrhea disease early stage erythrocyte sedimentation rate examination exhibited Fever headache Infection information Laboratory likelihood likelihood ratio Lymphocytes neutrophil Odds ratio Patient patients with COVID-19 positive predict Prevalence Probability progression Publication bia reduce mortality Result review searched sensitivity sensitivity analysis Severe patient severe patients Shortness of breath specificity Symptom Web of Science were assessed [DOI] 10.1155/2021/6671291 PMC 바로가기 [Article Type] Review Article
Demographic profile and outcome of patients admitted to a COVID dedicated hospital in Bangladesh during the second waveObservational Study Published on 2021-09-172022-10-05 Journal: Medicine [Category] 임상, [키워드] acute respiratory syndrome Admitted Patient age Care chronic renal disease clinical manifestations co-morbidity conducted coronavirus cough COVID COVID-19 cross-sectional demographic Diabetes Mellitus died female Fever hospital hypertension Infection intensive care lung involvement majority male Mortality mortality rate outcome overall mortality pandemic Patient predominant profile second wave Study design Symptom Symptoms the patient while with COVID-19 [DOI] 10.1097/MD.0000000000027281 PMC 바로가기 [Article Type] Observational Study
Chronic Diseases as a Predictor for Severity and Mortality of COVID-19: A Systematic Review With Cumulative Meta-AnalysisMedicine Published on 2021-09-012022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] acute respiratory distress Admission Aggressive Asthma Cancer Cerebrovascular disease chronic chronic disease Chronic diseases chronic liver disease chronic renal disease coronavirus disease country COVID-19 COVID-19 mortality COVID-19 pandemic COVID-19 patient COVID-19 patients COVID-19 severity cumulative cumulative meta-analysis Deterioration global healthcare greater higher risk hypertension ICU ICU admission identify index intensive care Meta-analysis Mortality Nursing obesity observational study Obstructive pandemic Patient patients with COVID-19 performed Predictive Probability pulmonary disease reduced risk review risk factor risk of bia searched severe COVID-19 severe symptom severity Symptom syndrome systematic review Web of Science [DOI] 10.3389/fmed.2021.588013 PMC 바로가기 [Article Type] Medicine
Risk factors for COVID-19-related in-hospital mortality in a high HIV and tuberculosis prevalence setting in South Africa: a cohort study남아프리카의 높은 HIV 및 결핵 유병률 환경에서 COVID-19 관련 병원 내 사망률의 위험 요소: 코호트 연구Article Published on 2021-09-012022-09-11 Journal: The Lancet. HIV [Category] SARS, 치료제, [키워드] 95% CI adjusted odds ratio African age Antiretroviral therapy ART Asthma available data benefit cardiac disease cause chronic cardiac disease chronic pulmonary disease chronic renal disease cohort study Comorbidities Comorbidity country COVID-19 death defined described diabete diabetes died discharge discharged Ethnicity excluded Factor Factors high risk HIV HIV infection HIV-uninfected hospital Hospital admissions Hospital mortality Hospital stay hypertension In-hospital in-hospital mortality Increasing increasing age individual individuals Infectious disease Interaction laboratory-confirmed SARS-CoV-2 infection male Male sex malignancy Missing data MOST multiple imputation multivariable logistic regression multivariable logistic regression models National non-communicable diseases number of comorbidity occurred Older Other outcome past Patient patients with COVID-19 people with HIV Prevalence public health random-effect renal disease reported risk risk factor Risk factors SARS-COV-2 infection Sex South South Africa submitted Surveillance Treatment Tuberculosis used data Vaccine was used were used [DOI] 10.1016/S2352-3018(21)00151-X PMC 바로가기 [Article Type] Article
Development and validation of a prognostic 40-day mortality risk model among hospitalized patients with COVID-19Observational Study Published on 2021-07-302022-10-04 Journal: PLoS ONE [Category] MERS, SARS, 임상, [키워드] 95% CI age calculator chronic renal disease Comorbidity comparison conditions Coronary artery disease COVID-19 COVID-19 mortality dataset death develop development Electronic health record facilitate Factor Follow-up hazard ratio hospital hospital discharge Hospitalization hospitalized COVID-19 hospitalized COVID-19 patient hospitalized patient hypertension Increases independent predictor median age Mortality mortality risk model New objective Oxygenation patient treatment patients died patients hospitalized polymerase chain positive Predictive Probability prognostic public health respiratory rate Result risk Risk scores SARS-CoV-2 study population the primary endpoint Therapeutic strategies USA variable with COVID-19 yielding [DOI] 10.1371/journal.pone.0255228 PMC 바로가기 [Article Type] Observational Study
COVID-19 and periodontitis: reflecting on a possible associationHypothesis Published on 2021-05-112022-10-31 Journal: Head & Face Medicine [Category] COVID-19, SARS, [키워드] addition association cardiovascular disease CD147 cells chronic disease chronic renal disease Clinical course coronavirus COVID-19 demonstrated Diabetes Mellitus expression greater hypertension IL-17 IL-6 infect Inflammatory Non-COVID-19 obesity occur oral disease overexpression pathophysiology pathway Periodontitis Perspective recent receptor SARS-CoV-2 Severe case virus worsening [DOI] 10.1186/s13005-021-00267-1 PMC 바로가기 [Article Type] Hypothesis
The effect of age on the association between diabetes and mortality in adult patients with COVID-19 in MexicoArticle Published on 2021-04-162022-10-29 Journal: Scientific Reports [Category] COVID-19, MERS, SARS, [키워드] 28-day mortality 95% CI 95% confidence interval adjusted adjusted hazard ratio age association calculate chronic renal disease COVID-19 death determine diabete diabetes died disease endocrinology example hazard ratio hospitalized patient hypertension immunodeficiency Infectious diseases Inpatient Inpatients involved laboratory-confirmed Mortality obesity Older Outpatient outpatients and inpatients Patient patients with COVID-19 patients without COVID-19 populations respiratory retrospective cohort study risk of death SARS-COV-2 infection screened severe COVID-19 Sex smoking Symptom System tested viral infection viral respiratory was used [DOI] 10.1038/s41598-021-88014-z PMC 바로가기 [Article Type] Article