Real-World Effectiveness of Cladribine for Patients with Multiple Sclerosis: A Sicilian Multicentric Experience (Rewind Study)article Published on 2024-02-122024-09-05 Journal: Current neuropharmacology [Category] update2024, [키워드] Cladribine Disease modifying therapies highly active treatment moderately active treatment multiple sclerosis switching therapies [DOI] 10.2174/1570159X21666230322140711 PMC 바로가기 [Article Type] article
Humoral immune response after SARS-CoV-2 vaccination in cladribine-treated multiple sclerosis patientsShort communication Published on 2024-01-202024-09-05 Journal: Vaccine: X [Category] update2024, [키워드] Cladribine COVID-19 multiple sclerosis vaccination [DOI] 10.1016/j.jvacx.2024.100445 PMC 바로가기 [Article Type] Short communication
Immune responses to SARS-CoV-2 vaccination in multiple sclerosis: a systematic review/meta-analysis다발성 경화증에서 SARS-CoV-2 백신 접종에 대한 면역 반응: 체계적인 검토/메타 분석Review Published on 2022-08-012022-09-11 Journal: Annals of Clinical and Translational Neurology [Category] COVID19(2023년), SARS, 치료기술, [키워드] Acetate Affect Alemtuzumab anti-CD20 Antibody detection Antibody Response Antibody responses Antibody testing applied CD20 cellular response Cellular responses Cladribine demonstrated dimethyl fumarate Epidemiology fumarate Glatiramer Glatiramer acetate Google Scholar HCs healthy control immune response Immunity inactivated independent interferon Interferon-beta mAb mAbs Meta-analysis meta-analysis and systematic review monoclonal antibody MOOSE mRNA mRNA vaccine mRNA vaccines multivariate logistic regression multivariate logistic regression model Natalizumab not affect observational studies observational study Odds ratio Patient positive predict response SARS-CoV-2 infections SARS-CoV-2 vaccination SARS-CoV-2 vaccine SARS-CoV-2 vaccines searched seroconversion rate seroconversion rates sphingosine-1-phosphate systematic review T cell T cell response T-cell Response T-cell responses Teriflunomide therapy Vaccine vaccine immunity vaccine response Vaccines vector virus [DOI] 10.1002/acn3.51628 PMC 바로가기 [Article Type] Review
Longitudinal humoral response in MS patients treated with cladribine tablets after receiving the second and third doses of SARS-CoV-2 mRNA vaccineSARS-CoV-2 mRNA 백신의 2차 및 3차 접종 후 클라드리빈 정제로 치료받은 MS 환자의 세로 체액 반응Article Published on 2022-07-012022-09-12 Journal: Multiple sclerosis and related disorders [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] addition booster Cladribine Cladribine tablets COVID-19 COVID-19 vaccination COVID-19 vaccine dose group HCs healthy control humoral IgG level immunomodulatory long term Long term serology response longitudinal maintain mRNA mRNA vaccine Multiple multiple sclerosis no difference Patient patients treated positive positive serology receive receiving robust SARS-CoV-2 SARS-CoV-2 vaccine second dose serological response serology significantly lower sustained Tablet Treatment Vaccine vaccine dose was tested [DOI] 10.1016/j.msard.2022.103863 PMC 바로가기 [Article Type] Article
Long term persistence of SARS-CoV-2 humoral response in multiple sclerosis subjects다발성 경화증 환자에서 SARS-CoV-2 체액 반응의 장기간 지속Article Published on 2022-06-012022-09-11 Journal: Multiple sclerosis and related disorders [Category] COVID19(2023년), MERS, SARS, 변종, 진단, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus age anti-Spike IgG anti-spike IgG levels appearance benefit BNT162b2 BNT162b2 mRNA BNT162b2 mRNA vaccine BNT162b2-mRNA vaccine booster booster vaccination booster vaccinations Cladribine Cohort comparable coronavirus Coronavirus-19 dimethyl fumarate Disease modifying therapies dose eight evaluated faster fingolimod Fingolimod- Glatiramer Glatiramer acetate groups healthy control healthy controls humoral humoral immune response Humoral persistence Humoral response IgG IgG levels interferon long term mRNA vaccine Multiple multiple sclerosis Natalizumab Ocrelizumab pandemic Patient patients persistence receiving regimen respiratory SARS-CoV-2 SARS-CoV-2 BNT162b2 SARS-CoV-2 IgG SARS-COV-2 infection SARS-CoV-2 spike protein severe acute respiratory syndrome Coronavirus spike Spike protein subject subjects Teriflunomide the SARS-CoV-2 titre variants [DOI] 10.1016/j.msard.2022.103800 PMC 바로가기 [Article Type] Article
Management of hepatitis B virus prophylaxis in patients treated with disease-modifying therapies for multiple sclerosis: a multicentric Italian retrospective studyArticle Published on 2022-06-012023-06-11 Journal: Journal of Neurology [Category] B형 간염, Fulltext, [키워드] Cladribine hepatitis B multiple sclerosis Ocrelizumab rituximab vaccination [DOI] 10.1007/s00415-022-11009-x PMC 바로가기
Humoral and Cellular Immune Responses to SARS-CoV-2 mRNA Vaccination in Patients with Multiple Sclerosis: An Israeli Multi-Center Experience Following 3 Vaccine Doses다발성 경화증 환자의 SARS-CoV-2 mRNA 백신 접종에 대한 체액 및 세포 면역 반응: 3회 백신 접종 후 이스라엘의 다기관 경험Multicenter Study Published on 2022-04-012022-09-11 Journal: Frontiers in Immunology [Category] COVID19(2023년), SARS, 진단, 치료기술, [키워드] Affect Autoimmunity Blood BNT162b2 booster cell-mediated immune response cellular response Cellular responses Cladribine contribute COVID-19 disease Disease modifying therapies (DMTs) evaluated experience fingolimod Fingolimod- healthy control humoral Humoral response humoral responses IFNγ IgG IgG level IgG levels immune immune response immune responses incubated Longevity MOST mRNA mRNA vaccine Multiple multiple sclerosis Ocrelizumab Patient patients proportion recovering from COVID-19 recruited response SARS-CoV-2 secretion seropositive subgroup analysis T-cell T-cell immune response T-cell Response T-cell responses therapy time interval treated vaccination Vaccinations was collected were measured with COVID-19 within 6 months [DOI] 10.3389/fimmu.2022.868915 PMC 바로가기 [Article Type] Multicenter Study
Humoral and cellular immune responses to SARS CoV-2 vaccination in People with Multiple Sclerosis and NMOSD patients receiving immunomodulatory treatments면역 조절 치료를 받는 다발성 경화증 환자 및 NMOSD 환자에서 SARS CoV-2 예방 접종에 대한 체액 및 세포 면역 반응Observational Study Published on 2022-03-012022-09-12 Journal: Multiple sclerosis and related disorders [Category] MERS, 임상, 진단, [키워드] Acetate B-cell B-cell response cellular Cellular immune response cellular immune responses Cladribine clinician Course COVID COVID 19 COVID19 depleting Dimethylfumarate disease humoral humoral immune response immune immunomodulatory immunomodulatory medications impair inhibitor Multiple Multiple Sclerosis therapy Natalizumab Neuromyelitis Optica not affect pandemic Patient quantified receiving reduced SARS CoV-2 SARS CoV2 sclerosis Support T cell responses T-cell responses Therapies therapy Treatment vaccination vaccination efficacy Viral antigen [DOI] 10.1016/j.msard.2022.103554 PMC 바로가기 [Article Type] Observational Study
Drugs Used in the Treatment of Multiple Sclerosis During COVID-19 Pandemic: A Critical ViewpointCovid-19 Pandemic 동안 다발성 경화증 치료에 사용되는 약물 : 중요한 관점Article Published on 2022-01-012022-08-31 Journal: Current neuropharmacology [Category] SARS, 치료제, [키워드] Acetate activating acute respiratory distress acute respiratory distress syndrome Alemtuzumab analogue antiviral activity approved ARDS autoimmune disorder Autoimmune disorders caution cellular Cladribine concern COVID-19 COVID-19 infection COVID-19 pandemic cytokine Cytokine storm Defense depleting detrimental dimethyl fumarate disease Disease-modifying therapy drug early stage endothelial example fingolimod fumarate Glatiramer Glatiramer acetate health problem hyperinflammation Hyperinflammatory IFN IFNs immunomodulation interfere interferon Invasion lung Macrophage mechanisms Multiple multiple sclerosis Natalizumab neuroprotection Nrf-2 nucleotide nucleotides Ocrelizumab other organs overcome oxidative stress pathway potential risk Protective public health raised reinforcement respiratory distress risk risk-benefit ratio. Safe SARS-CoV-2 SARS-COV-2 infection sclerosis suggested syndrome Teriflunomide Treatment Viral viral replication [DOI] 10.2174/1570159X19666210330094017 PMC 바로가기 [Article Type] Article
Anti-HBs titers are not decreased after treatment with oral Cladribine in patients with Multiple Sclerosis vaccinated against Hepatitis B virusArticle Published on 2022-01-012023-06-11 Journal: Multiple sclerosis and related disorders [Category] B형 간염, SARS, [키워드] Cladribine Hepatitis B virus Vaccine [DOI] 10.1016/j.msard.2021.103334