B-cell responses to vaccination with BNT162b2 and mRNA-1273 6 months after second doseBNT162b2 및 mRNA-1273 2차 접종 6개월 후 백신 접종에 대한 B 세포 반응Article Published on 2022-07-012022-09-12 Journal: Clinical microbiology and infection : the official [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] ACE2 age anti-SARS-CoV-2 antibody antibody association B-cell B-cell response binding binding antibody unit BNT162b2 characterized clinical consequence correlation COVID-19 dose examined Frame greater IgA IgG immune response Immunity Level majority marker mRNA-1273 mRNA-based vaccine NAb Neutralization assay neutralizing antibody optical participant Participants Prevalence reactive response SARS-CoV-2 second dose second vaccination Sex significantly the median titre vaccination [DOI] 10.1016/j.cmi.2022.02.028 PMC 바로가기 [Article Type] Article
Post-vaccination outcomes in association with four COVID-19 vaccines in the Kingdom of Bahrain바레인 왕국의 4가지 COVID-19 백신과 관련된 백신 접종 후 결과Article Published on 2022-06-022022-09-11 Journal: Scientific Reports [Category] COVID19(2023년), SARS, 변종, [키워드] age Analysis association AstraZeneca Bahrain can not clinical consequence confounding factors country COVID-19 COVID-19 case COVID-19 vaccine Critical database deaths delta variant effective Effectiveness estimate Evidence evidence of examined frequencies Frequency globe higher risk hospitalisation hospitalisations ICU admission ICU admissions individual individuals Infection infections Kingdom knowledge magnitude National new SARS-CoV-2 no evidence of outcome outcomes Pfizer Pfizer/BioNTech PROTECT question recipients reducing reported required SARS-CoV-2 infections SARS-CoV-2 variants significantly Sinopharm Support total population vaccination Vaccine Vaccines variant variants while wild type Wuhan [DOI] 10.1038/s41598-022-12543-4 PMC 바로가기 [Article Type] Article
Breakthrough infections after COVID-19 vaccination: Insights, perspectives and challengesResearch article Published on 2022-06-012022-10-05 Journal: Metabolism Open [Category] 변종, [키워드] acquisition administration age antibody Antigen Breakthrough infection breakthrough infections cause Characteristics clinical consequence Comorbidities COVID COVID-19 COVID-19 pandemic determinant Determining dose Effectiveness Host Immune escape immune evasion immune protection Immune status Immunity immunosuppressive drugs incidence Incubation period Infection Long Mortality mucosal nasal neutralizing antibody occur offer omicron Pancoronavirus pathogenicity Perspective platform plethora Public health intervention reduced reducing robust SARS-CoV-2 SARS-CoV-2 variant severe disease Severity of infection shown significantly Spread syndrome Transmissibility Transmission turn vaccinated individuals vaccination Vaccine Vaccines variant variant of concern viral variant virus [DOI] 10.1016/j.metop.2022.100180 [Article Type] Research article
A Cost-Effectiveness Analysis of Remdesivir for the Treatment of Hospitalized Patients With COVID-19 in England and WalesResearch article Published on 2022-05-012022-10-05 Journal: Value in health : the journal of the International [Category] 임상, 치료법, [키워드] Analysis approach assumption clinical consequence Cohort conducted coronavirus cost-effectiveness COVID-19 death Economic evaluation England Evidence hazard ratio Health technology assessment hospitalized patient hypothetical introduced large trial morbidity and mortality National Health Service objective parameters Prevent Probability Quality of life RDV reduce Remdesivir requiring supplemental oxygen resource Result SOC Standard of care survival threshold Treatment United Kingdom vaccination were used with COVID-19 [DOI] 10.1016/j.jval.2021.12.015 [Article Type] Research article
Quality of Life in Patients with Pancreatic Cancer before and during the COVID-19 PandemicObservational Study Published on 2022-03-212022-10-05 Journal: International Journal of Environmental Research an [Category] 임상, [키워드] addressed adverse outcome Affect Anxiety applied arising benefit Cancer cancer patient Care change Chemotherapy clinical consequence Cohort concerning conducted core coronavirus disease 19 COVID-19 COVID-19 pandemic Deterioration distress emotional European Health healthcare heterogenous highlight homogenous impairing indicated Intervention life limitation medium Mental outcome pancreatic Pancreatic cancer pancreatic tumor pandemic Patient patients Patients with cancer personal health physical Prolonged psychological support Quality Quality of life questionnaire recent regimen Resilience score Stress surgical survivor Treatment underlying disease urgency were expressed Worry [DOI] 10.3390/ijerph19063731 PMC 바로가기 [Article Type] Observational Study
[Analysis of ENT emergency patients during the COVID-19 pandemic in Germany]Observational Study Published on 2022-02-012022-10-05 Journal: Hno [Category] COVID19(2023년), SARS, 임상, [키워드] ambulatory Ambulatory care caused clinical consequence COVID-19 COVID-19 pandemic demographic Department diagnose Diagnosis diagnostics discrepancy Emergency emergency medicine English Epistaxis Health authority hospital hospitalisation Hospitalization limit material men multifactorial otolaryngology pandemic Patient patients physician Rate reduction in remained retrieved retrospective SARS-CoV-2 significantly the patient therapy trauma treated Treatment Triage urgency women [DOI] 10.1007/s00106-021-01121-1 PMC 바로가기 [Article Type] Observational Study
Multi‐omics of the expression and clinical outcomes of TMPRSS2 in human various cancers: A potential therapeutic target for COVID‐19인간의 다양한 암에서 TMPRSS2의 발현 및 임상 결과의 멀티오믹스: COVID-19의 잠재적 치료 표적Original Article Published on 2021-12-242022-09-10 Journal: Journal of Cellular and Molecular Medicine [Category] MERS, 바이오마커, [키워드] TMPRSS2 acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 analysed Analysis bioinformatics Biomarker Blood Brain Breast Cancer cancer progression cancers clinical consequence clinical consequences Clinical outcome Colorectal cancer contribute coronavirus coronavirus disease correlated correlation COVID‐19 DEGs effective Evidence expressed gene expression Genes Genetic variations humans Immune cell infiltration immune infiltration incidence Infection lung molecular multi‐omics analysis network analysis outbreak ovarian Pathway analysis Pathways Patient potential therapeutic target Prevent Prognosis prognostic prognostic analysis Prognostic biomarkers Prognostic value progression Protein regulate respiratory Respiratory system SARS‐CoV‐2 SARS‐CoV‐2 infection severe acute respiratory syndrome Coronavirus shown significantly Soft tissue therapeutic target tissue tissues TMPRSS2 transmembrane serine protease transmembrane serine protease 2 Tumours [DOI] 10.1111/jcmm.17090 PMC 바로가기 [Article Type] Original Article
Quercetin for COVID-19 and DENGUE co-infection: a potential therapeutic strategy of targeting critical host signal pathways triggered by SARS-CoV-2 and DENVCOVID-19 및 DENGUE 동시 감염에 대한 케르세틴: SARS-CoV-2 및 DENV에 의해 유발되는 중요한 숙주 신호 경로를 표적으로 하는 잠재적 치료 전략Article Published on 2021-11-052022-09-11 Journal: Briefings in Bioinformatics [Category] SARS, 유전자 메커니즘, [키워드] alleviate Analysis bioinformatics biological function Biological functions CCL-2 Clinical characteristics clinical consequence clinical consequences Co-infection Computational biology COVID-19 Critical current CXCL8 Cytokines cytokines release Dengue drug drug trial evaluate Evidence excessive immune response functional Host IL-17 immune responses indicated Inflammation inflammatory pathway inhibit Intervention mechanism mechanisms NF-κB overlapping pathway patients pharmacological pharmacological target potential molecular PPI protein-protein interaction public health quercetin SARS-CoV-2 shown signaling pathways target targets therapeutic therapeutic strategy TNFα Toll-like receptor toll-like receptor signaling Treatment treatment of COVID-19 triggered upstream virus [DOI] 10.1093/bib/bbab199 PMC 바로가기 [Article Type] Article
Endobronchial valve positioning for alveolar-pleural fistula following ICU management complicating COVID-19 pneumoniaCase Report Published on 2021-09-272022-10-28 Journal: BMC Pulmonary Medicine [Category] COVID-19, Fulltext, SARS, [키워드] acute respiratory syndrome affected Alveolar-pleural fistula ARDS Bacterial clinical consequence complex interaction coronavirus 2 COVID-19 EBV effective Endobronchial Endobronchial valve feasible ICU Infection Inflammation Injury invasive Invasive mechanical ventilation Klebsiella pneumoniae lung parenchyma lung tissue management mechanical ventilation Patient patients persistent Pneumonia Pneumothorax Respiratory failure SARS-CoV-2 Serious Adverse Events severity Stage subset therapeutic option treated [DOI] 10.1186/s12890-021-01653-w PMC 바로가기 [Article Type] Case Report
The Anti-SARS-CoV-2 Antibody Response in a Centenarian Woman: A Case of Long-Term Memory?100 세 여성의 항 -SARS-COV-2 항체 반응 : 장기 기억의 사례?Case Reports Published on 2021-08-272022-09-01 Journal: Viruses [Category] MERS, SARS, 진단, [키워드] absence addressed affected Anti-spike appear Asymptomatic B cell B cell memory B cells Blood cell-ELISA Centenarian classical clinical consequence clinical consequences conditions COVID-19 COVID-19 pandemic described ELISA heterogeneity heterogeneous highest highlight Host immune response IgG immune defense immune memory in vitro in vitro IgG increase in Infection long-term memory low-grade inflammation Manifestations memory memory B cells Mild mortality rate observation Occurrence Older plasma positive potential mechanism produced reached released reported respiratory response responsible SARS-CoV-2 SARS-COV-2 infection Serological testing serum severity specific antibodies specific antibody susceptibility syndrome the SARS-CoV-2 turn virus virus infection virus infections was tested while [DOI] 10.3390/v13091704 PMC 바로가기 [Article Type] Case Reports