Safety and Efficacy of Siddha Medicine preparation in the management of COVID-19: A Prospective Randomised Open Label StudyResearch article Published on 2022-07-012022-10-05 Journal: Journal of Ayurveda and Integrative Medicine [Category] 임상, [키워드] 1:1 adverse events age average AYUSH baseline breathing ambient air CAM therapy clinical marker clinical symptom clinical trial complementary conducted control group COVID 19 patients COVID-19 COVID-19 patients Efficacy and safety group hospitalisation Hospitalized interquartile range Intervention intervention group lAbel management Medicine Mild Moderate COVID-19 objective open label oxygen saturation pandemic participated Patient patients hospitalized primary end point Prospective randomised Randomized receiving reduction in reported Result Safety SARS-COV-2 infection Seven Siddha spread of COVID-19 standard care statistically Symptom therapy Traditional medicine Trial two group [DOI] 10.1016/j.jaim.2022.100597 [Article Type] Research article
The clinical course, biochemical markers, and clinical outcomes of COVID-19 positive patients from the third wave in Pakistan: A retrospective cohort studyResearch article Published on 2022-05-012022-10-05 Journal: Annals of Medicine and Surgery [Category] 바이오마커, [키워드] affected Analysis ARDS Asymptomatic being biochemical marker biochemical markers Case fatality rate Clinical course clinical marker Clinical outcome COVID-19 COVID-19 positive patient cumulative death diabete diagnosed with COVID-19 disease course disease severity Dyspnea expected expired Fever Gastrointestinal hypertension ICU include individual Infection intensive care patient interstitial Kaplan-Meier survival analysis median age Mortality non-survivor occurred outcomes pandemic patchy Patient PCR polymerase chain Predictive predominant Probability radiological finding recovered patient reduced Result retrospective cohort study SARS-CoV-2 second wave severity severity and prognosis surpassed survival survivor Symptom the patient transmissions variant ventilator X-ray [DOI] 10.1016/j.amsu.2022.103599 [Article Type] Research article
Specialized interferon action in COVID-19코로나19에 특화된 인터페론 작용Article Published on 2022-03-152022-09-11 Journal: Proceedings of the National Academy of Sciences of [Category] MERS, 유전자 메커니즘, 진단, [키워드] Activation Antiviral association C-reactive protein cell types circulating clinical marker clinical markers COVID-19 COVID-19 pathology CyTOF cytokine diagnostic disease severity Effect endothelial damage example Hospitalization hospitalized COVID-19 patients IFN IFN signaling IFNA2 IFNA6 IFNB1 IFNg IFNs Immune cell immune cell types immune cells immune marker Impact Implications interferon Kynurenine Kynurenine pathway lymphocyte lymphoid marker neutrophil pathology platelet activation poor prognosis Protective proteomics SARS-CoV-2 Seroconversion severe disease Signaling significant decrease subset the strongest therapeutic transcriptional response type I unique [DOI] 10.1073/pnas.2116730119 PMC 바로가기 [Article Type] Article
COVID-19 and adult-onset Still’s disease as part of hyperferritinemic syndromes고 페리틴혈증 증후군의 일부인 COVID-19 및 성인 발병 스틸병Case Reports Published on 2022-01-072022-09-12 Journal: Modern rheumatology case reports [Category] 진단, [키워드] adult onset Still’s disease catastrophic Chest computed tomography Ciclesonide clinical marker coronavirus disease COVID-19 COVID-19 infection cyclesonide Day diagnosed Diagnosis disease Dyspnea Efficacy expected ferritin Hyperferritinemia hyperferritinemic syndrome Including inflammatory markers Laboratory macrophage activation syndrome mild pneumonia occurrence of COVID-19 parameter Patient PCR test Prednisolone Septic shock Still Symptom syndrome TCZ the disease Tocilizumab Treatment while with COVID-19 [DOI] 10.1093/mrcr/rxab032 PMC 바로가기 [Article Type] Case Reports
Markers for severe disease and long-term sequelae in pediatric patients with severe acute respiratory syndrome coronavirus 2 infection중증 급성 호흡기 증후군 코로나바이러스 2 감염 소아 환자의 중증 질환 및 장기 후유증 표지자Article Published on 2022-01-012022-09-11 Journal: Pediatrics international : official journal of the [Category] SARS, 바이오마커, [키워드] abnormality acute COVID-19 acute disease acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Adolescence Adults Affect age age distribution bimodal Birth caused Chain Reaction Chest Chest radiograph children chronic chronic disease clinical marker clinical markers Comorbidity Complication coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 defined demographic determine disease Fewer patients infancy Infection Lung disease marker morbidity and mortality MOST obesity oxygen parameter Patient PCR pediatric pediatric COVID-19 Pediatric patient polymerase chain polymerase chain reaction positive positive pressure positive pressure ventilation pressure ventilation Research respiratory retrospective review SARS-CoV-2 SARS-CoV2 severe acute respiratory syndrome Coronavirus severe COVID-19 severe disease significantly supplemental oxygen Symptom symptomatic infection tertiary care hospital the disease [DOI] 10.1111/ped.15177 PMC 바로가기 [Article Type] Article
A randomized pilot study using calcitriol in hospitalized COVID-19 patients입원한 COVID-19 환자에서 칼시트리올을 사용한 무작위 파일럿 연구Randomized Controlled Trial Published on 2022-01-012022-09-11 Journal: Bone [Category] SARS, 비임상, 임상, [키워드] 1:1 14 subject 14 subjects adaptive Admission arterial oxygen saturation assigned average benefit breath calcitriol calculated clinical marker clinical trial consecutive patients control group COVID-19 death discharge discharged Endocrine enrolled Enrollment expression FiO2 fraction groups Health care health care systems hospital hospital discharge Hospitalization Hospitalized hospitalized COVID-19 patient hospitalized patient hospitalized patients ICU immune function include open label Other oxygen oxygen saturation oxygen supplementation Oxygenation Patient patients hospitalized patients with COVID-19 physiologic function pilot study Randomized randomized clinical trial randomized trial Randomly readmission regulate Regulation required room air SARS-COV-2 infection subject systemic illness therapy transfer treated Treatment Trial Vitamin D with COVID-19 [DOI] 10.1016/j.bone.2021.116175 PMC 바로가기 [Article Type] Randomized Controlled Trial
Severity-associated markers and assessment model for predicting the severity of COVID-19: a retrospective study in Hangzhou, ChinaCovid-19의 심각성을 예측하기위한 심각도 관련 마커 및 평가 모델 : 중국 항저우의 후 향적 연구Research Article Published on 2021-08-092022-09-10 Journal: BMC Infectious Diseases [Category] MERS, SARS, 바이오마커, [키워드] 95% CI Admission albumin assessment Assessment model AUROC AUROCs best bootstrap C-reactive protein calibration curve China clinical decision clinical marker Clinical practice Clinical treatment clinician Coagulation coagulation function Comorbidity COVID-19 COVID-19 patient COVID-19 patients Critical cutoff value Decision making develop eight electrolyte disturbance enrolled eosinophil evaluate external validation Fever help hospital internal internal and external Laboratory Lactate lactate dehydrogenase LASSO likelihood Logistic regression lymphocyte Lymphocyte count lymphocyte counts marker measure ordinal logistic regression Patient prediction Prognosis random Random forest Receiver operator characteristic Regression model Result Retrospective study risk sampling Selection Sensitivity and specificity severity severity of COVID-19 Shrinkage supplementary material Support support vector machine training set was performed was used Web-based assessment system [DOI] 10.1186/s12879-021-06509-6 PMC 바로가기 [Article Type] Research Article
Predictive Modeling of Morbidity and Mortality in Patients Hospitalized With COVID-19 and its Clinical Implications: Algorithm Development and InterpretationOriginal Paper Published on 2021-07-092022-10-30 Journal: Journal of Medical Internet Research [Category] COVID-19, SARS, [키워드] 24 hour 24 hours age assist AUC Blood urea nitrogen C-reactive protein canonical markers clinical clinical activity Clinical data clinical decision clinical marker coronavirus COVID-19 COVID-19 pandemic Deceased Decision making development Diabetic Disease progression disease severity effort elevated Endpoint Factor feature Final Glucose Gradient Health care system highest hospital Hospital stay Hospitalization ICU identify intensive care lab value lactate dehydrogenase LDH machine learning marker Model modeling morbidity morbidity and mortality Mortality New York New York City objective offered outcome outcomes Patient patient data performance peripheral oxygen saturation positive predict prediction Predictive Predictive modeling respiration rate Result Retrospective study risk SARS-CoV-2 severity strain Symptom temperature tested treated university Ventilated was obtained with COVID-19 [DOI] 10.2196/29514 PMC 바로가기 [Article Type] Original Paper
Comparison of three serological chemiluminescence immunoassays for SARS-CoV-2, and clinical significance of antibody index with disease severitySARS-COV-2에 대한 3 개의 혈청 발광 면역 분석 및 질병 중증도에 대한 항체 지수의 임상 적 중요성의 비교Comparative Study Published on 2021-06-292022-09-10 Journal: PLoS ONE [Category] MERS, SARS, 바이오마커, 진단, 치료법, [키워드] (Abbott Abbott access acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 antibody automated Beckman Coulter chemiluminescence immunoassay clinical implication clinical implications clinical marker clinical markers Clinical severity Clinical significance collected coronavirus correlation correlation coefficient COVID-19 disease disease severity IgG IgG antibody IgM immunoassay Infection investigated Molecular tests nucleocapsid nucleocapsids Patient patients with COVID-19 Quantitative respiratory Result SARS-CoV-2 SARS-CoV-2 antibody SARS-CoV-2 IgG SARS-CoV-2 IgG antibody SARS-CoV2 serological severe acute respiratory syndrome Coronavirus severe disease Siemens significantly significantly higher specimen spikes statistically the SARS-CoV-2 Total was measured [DOI] 10.1371/journal.pone.0253889 PMC 바로가기 [Article Type] Comparative Study
Could serum albumin value and thrombocyte/lymphocyte ratio be an important prognostic factor in determining the severity of COVID 19?혈청 알부민 값과 혈소판/림프구 비율이 COVID 19의 중증도를 결정하는 중요한 예후 인자가 될 수 있습니까?Article Published on 2021-06-282022-09-10 Journal: Turkish Journal of Medical Sciences [Category] MERS, SARS, 바이오마커, [키워드] Admission age albumin an area area of interest clinical marker clinical markers Comorbidity COVID demographic demographic data evaluate Follow-up groups highest hospital Hospitalization ICU intensive care lymphocyte Lymphocyte count material Older Patient patients with COVID-19 platelet lenfosit ratio Prognostic factor Result risk Risk assessment serum albumin serum albumin value severity Severity of COVID 19 Severity of disease Sex statistically significant difference the disease thrombocyte two group two groups were recorded [DOI] 10.3906/sag-2008-285 PMC 바로가기 [Article Type] Article