Smoking modulates different secretory subpopulations expressing SARS-CoV-2 entry genes in the nasal and bronchial airwaysArticle Published on 2022-10-282022-11-16 Journal: Scientific Reports [Category] COVID19(2023년), SARS, 치료기술, [키워드] ACE2 airway airway epithelium airways association C15orf48 cell population changes in characterized club co-expressed cohorts CTSL diagnostic workup disease severity elevated epithelial cells expressed expressing expression expression data Gene Expression gene expression pattern Goblet cell increase in indicated individual Infection lung cancer lung cancer risk modulate modulated nasal Population SARS-CoV-2 SARS-CoV-2 entry SARS-COV-2 infection scRNA-seq secretory cell severe disease significantly similarity smoker smoking smoking status subpopulation TMPRSS2 viral entry Viral load [DOI] 10.1038/s41598-022-17832-6 PMC 바로가기
Serine Protease Inhibitors Restrict Host Susceptibility to SARS-CoV-2 Infections세린 프로테아제 억제제는 SARS-CoV-2 감염에 대한 숙주 감수성을 제한합니다Article Published on 2022-06-282022-09-11 Journal: mBio [Category] COVID19(2023년), SARS, 유전자 메커니즘, 치료제, [키워드] A1AT acute respiratory syndrome Administered Affect affecting age Alpha alpha-1-antitrypsin antithrombin III antitrypsin Antiviral antiviral drug antiviral intervention approach asymptomatic infection asymptomatic infections ATIII can be used cellular cellular protease ciliated cleavage club Comorbidities Comorbidity complex coronavirus disease Coronavirus disease 2019 COVID-19 deficiency determinant determinants disease disease severity Donor door expression expression level Factor Genetic Genetic variation Genetic variations goblet cells highlight Host human donors identification identify identity immune response individual Infection inhibitor inhibitors less lung cell mechanism mechanism of action outcome PAI1 Patient patients plasminogen activator inhibitor 1 Potential potential treatments primary cell primary cells reduce reducing regulate restrict risk risk factor Risk factors SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 susceptibility Serine serine protease serine protease inhibitor serine protease inhibitors serpin serpin. SERPINA1 SERPINE1 SERPINE2 serpins Severe acute respiratory syndrome severe COVID-19 severe infections Sex Single-cell RNA sequencing Spike protein susceptibility susceptible Symptom target cells TMPRSS2 Treatment Usage Variation viral burden viral entry viral spike protein [DOI] 10.1128/mbio.00892-22 PMC 바로가기 [Article Type] Article
New Psychoactive Substances and receding COVID-19 pandemic: really going back to “normal”?새로운 정신 활성 물질과 코로나19 대유행 퇴조: 정말 "정상"으로 돌아가는가?Article Published on 2022-05-112022-09-11 Journal: Acta bio-medica : Atenei Parmensis [Category] COVID19(2023년), SARS, 변종, 치료기술, [키워드] Abuse agency analogue Analysis appear approach arising available data benzimidazole can not Case report case reports Characteristics check circumvent clonitazene club compounds COVID-19 COVID-19 pandemic criminal criminality Dark Web death deaths derivative detectable detection system disorders diversion dosages drug Drug Abuse early stage early stages ecosystem Effect effective Effects effort Endemic etonitazene European Exacerbation fatality fentanyl FIVE form Health Service Health services healthcare implicated implication increasingly information Interaction involved isotonitazene less magnitude mechanism media metonitazene mistake Mortality New nine NMR NPs opioid opioids Opioids abuse overdose pandemic Probing public health public health emergency Public health responses receptor reduction Reduction potential replicate Research resource rising risk Scientific community seeking selected significantly more social media Still Stress substance substance abuse supply supply and demand Surveillance the SARS-CoV-2 traffickers turn urgency user experience variants web-based platform X-ray diffraction [DOI] 10.23750/abm.v93i2.13008 PMC 바로가기 [Article Type] Article
LaLiga Lockdown: Conditioning Strategy and Adaptation to In-Game Regulations during COVID-19 Pandemic Prevented an Increase in Injury IncidenceArticle Published on 2022-03-022022-10-29 Journal: International Journal of Environmental Research an [Category] COVID-19, MERS, SARS, [키워드] adaptation adopted Affect club competing Conditioning COVID-19 determine distribution elite athlete First wave football performance Health authority incidence increase Injury injury risk lockdown modify muscle injury Regulation severity significantly soccer Spanish Strategy [DOI] 10.3390/ijerph19052920 PMC 바로가기 [Article Type] Article
COVID-19 mitigation measures in primary schools and association with infection and school staff wellbeing: An observational survey linked with routine data in Wales, UKClinical Trial Published on 2022-02-282022-10-04 Journal: PLoS ONE [Category] COVID19(2023년), MERS, SARS, 임상, [키워드] activities adjusted Anxiety association children club conducted Contact COVID-19 COVID-19 case COVID-19 mitigation COVID-19 mitigation measure COVID-19 test Depression Evidence Impact impacted Implementing Infection infection rate infection rates likelihood linkage Local Logistic regression Lower measure Measures participant positive primary school pupil Pupils raise reducing reported respiratory infection response Result School social distancing staff Symptoms with COVID-19 [DOI] 10.1371/journal.pone.0264023 PMC 바로가기 [Article Type] Clinical Trial
An Exploration of Nutritional Education within the Holiday Activities and Food Programme in EnglandArticle Published on 2022-02-192022-10-29 Journal: International Journal of Environmental Research an [Category] Coronavirus, COVID19(2023년), MERS, SARS, [키워드] activity Analysis authority club Community conducted COVID Department for Education dietary intake education England ENhance example exploration facilitators food food insecurity food literacy Guidance HAF holiday activities and food holiday hunger holiday programme Impact impacts implementation IMPROVE include Inclusion involved knowledge mandatory mechanism nutritional education provide recruit required Research School School holidays suggested variety was used [DOI] 10.3390/ijerph19042398 PMC 바로가기 [Article Type] Article
SP-D and CC-16 Pneumoproteins’ Kinetics and Their Predictive Role During SARS-CoV-2 InfectionMedicine Published on 2022-02-082022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] acute respiratory distress acute respiratory distress syndrome age Analysis ARDS association Biomarker blood sample body mass index cell protein club club cell 16 protein collected confounding variable coronavirus correlated COVID-19 death Defense determine Diabetes Mellitus Dyspnea higher risk Hospital admission Host hypertension incidence increase in independent Inflammation initial involved Kinetics Multivariate analysis Neutrophil-to-lymphocyte ratio outcome oxidative stress Patient patients with COVID-19 performed positively correlated predict Predictive Prognosis Prognostic factor Protein Result Retrospective study role SARS-CoV-2 Serum level subsequent surfactant Surfactant protein D syndrome viral outbreak [DOI] 10.3389/fmed.2021.761299 PMC 바로가기 [Article Type] Medicine
A case report of COVID-19 monitoring in the Austrian professional football leagueArticle Published on 2021-12-242022-10-29 Journal: Scientific Reports [Category] COVID-19, SARS, [키워드] activities Case report club collected consequence Contact cooperation COVID COVID-19 COVID-19 case Epidemiology FIVE health parameters help hypothetical implementation Infection involved Medical research National observation period occurred pandemic PCR Perceived risk problem Reproduction number Simulation Subjective suggested [DOI] 10.1038/s41598-021-03820-9 PMC 바로가기 [Article Type] Article
The Impact of COVID-19 on Physical Performance and Mental Health—A Retrospective Case Series of Belgian Male Professional Football PlayersSports and Active Living Published on 2021-12-132022-10-31 Journal: Frontiers in Sports and Active Living [Category] COVID-19, [키워드] affected affecting Analysis Antwerp applied assessment Athletes Bonferroni correction cardiovascular system club complex Contamination COVID-19 COVID-19 contamination COVID-19 infection disorder Duration first positive Football General population Impact Lungs Mental mental health Muscle strength nose swab outcome PCR test performance physical positive positive COVID-19 professional questionnaire reduction SARS-CoV-2 Sery significantly statistical analysis statistically significant difference stress level tested was performed weakness Weekly were assessed were infected [DOI] 10.3389/fspor.2021.803130 PMC 바로가기 [Article Type] Sports and Active Living
A Machine Learning Approach to Analyze Home Advantage during COVID-19 Pandemic Period with Regards to Margin of Victory and to Different Tournaments in Professional Rugby Union Competitions코로나19 팬데믹 기간 동안 홈 어드밴티지를 분석하기 위한 머신 러닝 접근법Article Published on 2021-12-022022-09-10 Journal: International Journal of Environmental Research an [Category] SARS, 치료기술, [키워드] absence analyzed CHAID club competition complex contribute COVID-19 COVID-19 pandemic decision trees determinants evidenced Final home home advantage Interaction less machine learning margin of victory outcome pandemic Period Perspective positive professional rugby union southern hemisphere Support tendency the mean tournament union unique [DOI] 10.3390/ijerph182312711 PMC 바로가기 [Article Type] Article