Electrochemical paper-based antigen sensing platform using plant-derived monoclonal antibody for detecting SARS-CoV-2Article Published on 2023-01-012022-11-15 Journal: Talanta [Category] SARS, 진단, 치료기술, 치료제, [키워드] anti-SARS-CoV-2 antibody Antigen applicability applied approach Cellulose Concentration COVID-19 diagnosis CR3022 detect diagnostic Differential pulse voltammetry expressed functional group limit of detection linear relationship monoclonal antibody nasopharyngeal swab sample Nicotiana benthamiana Paper-based electrochemical immunosensor Plant-based antibody platform point-of-care pulse quantification RBD Receptor binding domain Saliva SAR-CoV-2 SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2. Spike protein the RBD this system was performed [DOI] 10.1016/j.talanta.2022.123783 PMC 바로가기
Quantifying the relationship between sub-population wastewater samples and community-wide SARS-CoV-2 seroprevalenceArticle Published on 2022-12-202022-11-15 Journal: The Science of the total environment [Category] COVID19(2023년), SARS, 진단, [키워드] Analysis assessment average Community Concentration conducted convenience sampling correlated correlation COVID-19 Disease prevalence Epidemic epidemiological Epidemiology estimate Health incidence rate increase in indicate Infection inherent biases Participants Prevalence prevalence rate Randomized regression analysis robust SARS-CoV-2 SARS-CoV-2 antibody SARS-COV-2 infection SARS-CoV-2 seroprevalence serological sewer Spread stratified Stratified randomized sampling the disease USA Wastewater-based epidemiology. [DOI] 10.1016/j.scitotenv.2022.158567 PMC 바로가기
Ultraminiature optical fiber-tip directly-printed plasmonic biosensors for label-free biodetectionArticle Published on 2022-12-152022-11-15 Journal: Biosensors & bioelectronics [Category] COVID19(2023년), SARS, 치료기술, [키워드] Additive Additive printing antibody AuNP Biomarker Concentration coronavirus disease detect Diagnosis diagnostics disease Diseases DNA sequence fiber gold Gold nanoparticle Gold nanoparticles imperative in vivo miniaturization offer optical Optical fiber optical fiber sensors pandemic Plasmonic biosensor point-of-care Precision Precision photoreduction. provide public health crisis SARS-CoV-2 [DOI] 10.1016/j.bios.2022.114761 PMC 바로가기
Application of neighborhood-scale wastewater-based epidemiology in low COVID-19 incidence situationsArticle Published on 2022-12-152022-11-16 Journal: The Science of the total environment [Category] COVID19(2023년), SARS, 변종, [키워드] application applied approach average characterized Concentration COVID-19 COVID-19 incidence Disease surveillance effective Epidemiology incidence rate infections less limit local outbreak Low COVID-19 incidence Mild N gene Neighborhood-scale sewersheds normalized outbreak plant public health measure quantification reported RT-qPCR SARS-CoV-2 SARS-CoV-2 N gene SARS-CoV-2 variant-specific RT-qPCR assays sensitivity Seven specificity statistically Surveillance the SARS-CoV-2 threshold Treatment virus Wastewater-based epidemiology. [DOI] 10.1016/j.scitotenv.2022.158448 PMC 바로가기
Changes of Routine Hematological Parameters in COVID-19 Patients: Correlation with Imaging Findings, RT-PCR and OutcomeOriginal Article Published on 2022-12-152022-10-29 Journal: Iranian Journal of Pathology [Category] COVID-19, [키워드] Admission age analyses Biochemical parameters Blood change Chest chest imaging Chest tomography Concentration Coronavirus disease 2019 correlated correlation correlations COVID-19 COVID-19 case COVID-19 patient Critical CRP CT-scan demonstrated diagnosed Diagnosis during admission enrolled evaluated expired group hematologic hematology hemoglobin Hospitalized imaging investigated Laboratory LDH less leukocyte lung lung involvement Lymphocytes neutrophil no increase outcome parameter parameters participant Patient patients Platelet platelets count Prognostic value raise researcher respiratory viral routine RT-PCR severity Severity of disease the disease tomography Tomography scanners upper respiratory Viral load WBC were measured White blood cells [DOI] 10.30699/IJP.2021.533645.2675 PMC 바로가기 [Article Type] Original Article
Pulmonary delivery of favipiravir inhalation solution for COVID-19 treatment: in vitro characterization, stability, in vitro cytotoxicity, and antiviral activity using real time cell analysisArticle Published on 2022-12-012022-11-15 Journal: Drug Delivery [Category] COVID19(2023년), SARS, 치료제, [키워드] addition administration Analysis Antiviral antiviral activity Calu-3 Cell characterized Concentration COVID-19 cytotoxicity Favipiravir in vitro indicated Influenza virus Inhaled inhaled formulation inhibitor investigated lung lung epithelial cell lung tissue Lungs media Patient patients with COVID-19 PBS phosphate buffer profile pulmonary RdRP real time required respiratory. RNA-dependent RNA polymerase SARS-CoV-2 stability target Toxicity treat Treatment VERO-E6 viability were infected [DOI] 10.1080/10717544.2022.2118398 PMC 바로가기
Folic acid: a potential inhibitor against SARS-CoV-2 nucleocapsid protein엽산: SARS-CoV-2 뉴클레오캡시드 단백질에 대한 잠재적 억제제Article Published on 2022-12-012022-09-11 Journal: Pharmaceutical Biology [Category] COVID19(2023년), SARS, 유전자 메커니즘, 치료법, [키워드] analysed Analysis antagonist antiviral effects antivirus association cellular Chinese Chinese medicine Compound Concentration coronavirus disease Coronavirus disease 2019 COVID-19 Data analysis docking drug target experiment Folic acid Genes global pandemic Host hub genes identify inhibit inhibition inhibitor involved material mCherry mCherry expression mechanism molecular molecular docking network pharmacology Network pharmacology. Nucleocapsid phosphoprotein Phosphoprotein Protein Regulatory RNA interference RNAi SARS-CoV-2 SARS-CoV-2 N SARS-CoV-2 nucleocapsid screened shown target targets therapeutic target Traditional Traditional Chinese medicine virus [DOI] 10.1080/13880209.2022.2063341 PMC 바로가기 [Article Type] Article
Immunodeficient patient experience of emergency switch from intravenous to rapid push subcutaneous immunoglobulin replacement therapy during coronavirus disease 2019 shieldingArticle Published on 2022-12-012022-11-15 Journal: Current opinion in allergy and clinical immunology [Category] 진단, [키워드] administration Anxiety assessment collected Concentration coronavirus disease COVID-19 greater high risk IgG IgG level immunodeficient patient Immunoglobulin immunoglobulin replacement therapy In-hospital Infection intravenous Intravenous immunoglobulin IVIG Laboratory Measures mitigate outcome Patient receiving recent reported risk severe coronavirus disease shielding subcutaneously Subjective transitioned [DOI] 10.1097/ACI.0000000000000864 PMC 바로가기
Clinical utility of circulating calprotectin to assist prediction and monitoring of COVID-19 severity: An Italian studyArticle Published on 2022-12-012022-11-15 Journal: Journal of medical virology [Category] 바이오마커, [키워드] Administered Admission assist Biomarker calprotectin Care chemiluminescent immunoassay circulating Circulating calprotectin clinical Cohort collected Concentration controls correlation COVID-19 COVID-19 pandemic COVID-19 patient COVID-19 patients disease severity evaluate healthy individual ICU intubation Italian study median Patient positive airway pressure Respiratory Support risk risk assessment. Sample serological serum severity of COVID-19 Severity of disease significantly higher tested utility were used [DOI] 10.1002/jmv.28056 PMC 바로가기
Surveillance of SARS-CoV-2 in nine neighborhood sewersheds in Detroit Tri-County area, United States: Assessing per capita SARS-CoV-2 estimations and COVID-19 incidenceResearch article Published on 2022-12-012022-10-05 Journal: The Science of the total environment [Category] COVID19(2023년), SARS, 바이오마커, 치료기술, [키워드] 5-hydroxyindoleacetic acid acute respiratory syndrome Assessing Biomarker Biomarkers collected Community Comparisons Concentration coronavirus correlation COVID-19 COVID-19 burdens COVID-19 case COVID-19 incidence creatinine cumulative demographic characteristics demographics Detroit Detroit Tri-County area Epidemiology genomic indicate Infection N1 and N2 nine normalized parameter polymerase chain Population predict quantified reduced RNA concentration SARS-CoV-2 SARS-CoV-2 RNA normalization screened selected suggested the disease transcriptase wastewater Wastewater-based epidemiology with COVID-19 xanthine [DOI] 10.1016/j.scitotenv.2022.158350 [Article Type] Research article