Dihydroartemisinin Disrupts Zinc Homeostasis in Plasmodium falciparum To Potentiate Its Antimalarial Action via PyknosisArticle Published on 2023-07-142024-08-29 Journal: ACS Infectious Diseases [Category] 말라리아, [키워드] dihydroartemisinin Plasmodium falciparum zinc depletion zinc homeostasis.
Impact of population based indoor residual spraying with and without mass drug administration with dihydroartemisinin-piperaquine on malaria prevalence in a high transmission setting: a quasi-experimental controlled before-and-after trial in northeastern Uganda인구 기반 실내 잔여 분무와 디하이드로아르테미시닌-피페라퀸을 이용한 대량 약물 투여의 유무가 높은 전파 환경에서 말라리아 유병률에 미치는 영향: 우간다 북동부에서의 준실험적 통제 전후 시험Article Published on 2023-02-062024-08-01 Journal: BMC Infectious Diseases [Category] 말라리아, [키워드] Controlled trial dihydroartemisinin High burden IRS malaria MDA Pirimiphos Uganda [DOI] 10.1186/s12879-023-07991-w PMC 바로가기
The effect of sickle cell genotype on the pharmacokinetic properties of artemether-lumefantrine in Tanzanian childrenarticle Published on 2022-08-312024-09-01 Journal: International Journal for Parasitology: Drugs and Drug Resistance [Category] 말라리아, [키워드] Artemether children Desbutyl-lumefantrine dihydroartemisinin Lumefantrine Population pharmacokinetics Sickle cell disease sickle cell trait Tanzania [Article Type] article
SARS-CoV-2 and Plasmodium falciparum Co-Infection in a Returning Traveler돌아오는 여행자의 SARS-CoV-2 및 Plasmodium falciparum 공동 감염Article Published on 2022-08-052022-09-11 Journal: Frontiers in Public Health [Category] SARS, 말라리아, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Administered Anxiety Arbidol China Co-infection Compound coronavirus coronavirus disease Coronavirus disease 2019 country COVID-19 Diagnosis diazepam dihydroartemisinin discharge discharged Diseases Evidence evidence of health system Healthcare system Hospitalization hydrochloride inflammatory reactions Insomnia interferon Lopinavir LOPINAVIR AND RITONAVIR malaria Mental no evidence of offer P. falciparum pandemic Paroxetine Paroxetine Hydrochloride Piperaquine Plasmodium Plasmodium falciparum raise reported Ritonavir SARS-CoV-2 severe acute respiratory syndrome Coronavirus sub-Saharan Africa Tablet tablets Tartrate tested the patient thymosin Treatment vital sign zolpidem Zolpidem Tartrate [DOI] 10.3389/fpubh.2022.871374 PMC 바로가기 [Article Type] Article
Ferroptosis plays an essential role in the antimalarial mechanism of low-dose dihydroartemisininarticle Published on 2022-04-302024-09-01 Journal: Biomedicine & Pharmacotherapy [Category] 말라리아, [키워드] Anti-malarial drug combinations dihydroartemisinin Ferroptosis malaria [Article Type] article
Dihydroartemisinin attenuates pulmonary inflammation and fibrosis in rats by suppressing JAK2/STAT3 signalingResearch Paper Published on 2022-02-152022-10-28 Journal: Aging (Albany NY) [Category] COVID-19, [키워드] activated Activation alveolar inflammation analyzed attenuate cause caused CCL3 change chemokine collagen Coronavirus disease 2019 COVID-19 dihydroartemisinin effective expression fibrosis growth hydroxyproline IL-6 Inflammatory response inhibit inhibited inhibiting inhibitory effect JAK2 JAK2/STAT3 JAK2/STAT3 signaling janus lung Lung injury lung tissue molecular analysis molecular mechanism Necrosis phosphorylated pulmonary fibrosis pulmonary inflammation reduced representing SARS-CoV-2 serum Signaling staining STAT3 TGF-β1 therapeutic therapeutic effect TNFα treat Treatment with COVID-19 worldwide pandemic [DOI] 10.18632/aging.203874 PMC 바로가기 [Article Type] Research Paper
A Nanodrug Coated with Membrane from Brain Microvascular Endothelial Cells Protects against Experimental Cerebral MalariaArticle Published on 2022-01-122024-08-28 Journal: Nano Letters [Category] 말라리아, [키워드] cell-membrane coating dihydroartemisinin experimental cerebral malaria malaria nanodrug.
Pyronaridine-Artesunate (Pyramax) for Treatment of Artemisinin- and Piperaquine-Resistant Plasmodium falciparum in the Central Highlands of VietnamArticle Published on 2021-11-172024-08-28 Journal: Med Instrum [Category] 말라리아, [키워드] antimalarial drug resistance Central Highlands dihydroartemisinin exo-E415G Pfcrt pfkelch13 Pfmdr1 Piperaquine plasmepsin 2/3 Plasmodium falciparum Pyramax pyronaridine Pyronaridine-artesunate Vietnam
Effect of Body Weight and Age on the Pharmacokinetics of Dihydroartemisinin: Food and Drug Administration Basis for Dose Determination of Artesunate for Injection in Pediatric Patients With Severe MalariaArticle Published on 2021-09-072024-08-28 Journal: Clinical infectious diseases : an official publication of the Infectious [Category] 말라리아, [키워드] artesunate dihydroartemisinin pediatric dose selection pharmacokinetic modeling and simulation severe malaria
Multidrug-Resistant Plasmodium falciparum Parasites in the Central Highlands of Vietnam Jeopardize Malaria Control and Elimination StrategiesArticle Published on 2021-03-182024-08-28 Journal: Med Instrum [Category] 말라리아, [키워드] dihydroartemisinin falciparum malaria Pfcrt pfkelch13 Piperaquine plasmepsin 2/3 pyronaridine resistance. Vietnam