Short-term exposure of the mayfly larvae (Cloeon dipterum, Ephemeroptera: Baetidae) to SARS-CoV-2-derived peptides and other emerging pollutants: A new threat for the aquatic environmentsArticle Published on 2022-11-252022-11-15 Journal: The Science of the total environment [Category] SARS, 바이오마커, [키워드] acetylcholinesterase addition ambient aquatic environment aquatic environments Biomarker Biomarkers Cloeon Combination concentrations coronavirus dismutase DPPH ecosystem Effect evaluate evidenced Freshwater ecosystems groups hospital Impact Insects Mortality New coronavirus nitrite Non-target organisms novel Novel coronavirus organism Organisms PCA peptide peptides principal component analysis raised reduced response risk SARS-CoV-2 scavenging significantly lower similarity Spread Stress Topic Treatment viral peptide [DOI] 10.1016/j.scitotenv.2022.157813 PMC 바로가기
Exploratory analysis of interleukin-38 in hospitalized COVID-19 patientsArticle Published on 2022-11-012022-11-15 Journal: Immunity, Inflammation and Disease [Category] SARS, 바이오마커, [키워드] Adaptive immune response Admission age Analysis anti-inflammatory effect anti-inflammatory properties binding Biomarker cartilage CD244 CHL1 circulating Clinical data Cohort cohorts Concentration concentrations coronavirus disease correlated correlation COVID-19 COVID-19 patient COVID-19 severity disease dismutase dysregulated enzyme-linked immunosorbent exploratory fatty healthy control healthy controls healthy subjects hospital Hospitalization hospitalized COVID-19 patient hospitalized COVID-19 patients IL-1 Immunoglobulin in viral increase in infections Inflammatory biomarker intensive care interleukin-38 investigated men moderate Mortality no difference outcome plasma positive correlation positively correlated progression Protein proximity extension assay recent receptor reduce retrieved retrospective cohort study SARS-CoV-2 SERPINA12 severity shown subjects thrombocyte TNF TNFRSF9 validation cohort were measured while women [DOI] 10.1002/iid3.712 PMC 바로가기
Oxidative Stress Markers and Sperm DNA Fragmentation in Men Recovered from COVID-19Article Published on 2022-09-022022-11-15 Journal: International Journal of Molecular Sciences [Category] SARS, 바이오마커, [키워드] 8-hydroxy-2′-deoxyguanosine Affect age-matched control antioxidant biochemical catalase Cell change Characteristics component consequence coronavirus Coronavirus infection correlated COVID-19 demonstrated dismutase DNA DNA fragmentation Factors FIVE fragmentation impair independent investigated male mechanisms men nitrotyrosine oxidative stress parameters patients recovered SARS-CoV-2 Semen semen sample Sperm spermatogenic cell spermatozoa Superoxide Dismutase total antioxidant capacity uric acid were assessed Zinc [DOI] 10.3390/ijms231710060 PMC 바로가기
Can spike fragments of SARS-CoV-2 induce genomic instability and DNA damage in the guppy, Poecilia reticulate? An unexpected effect of the COVID-19 pandemicSARS-CoV-2의 스파이크 조각이 구피 포에실리아 망상체의 게놈 불안정성과 DNA 손상을 유발할 수 있습니까? COVID-19 전염병의 예상치 못한 영향Article Published on 2022-06-152022-09-11 Journal: The Science of the total environment [Category] COVID19(2023년), SARS, 변종, [키워드] animals Brain Can catalase correlated COVID-19 COVID-19 pandemic demonstrated dismutase dispersal DNA damage ecosystem Effect ENA evaluate Frequency Freshwater fish gel electrophoresis genomic genotoxic genotoxicity Impact increase in induce knowledge lipid peroxidation liver malondialdehyde mutagenic Mutagenicity New coronavirus nuclear Olive Organisms parameter peptide peptides Protein raised reduction reported SARS-CoV-2 SARS-CoV-2 particle SARS-CoV-2 particles significantly Single Cell Spike protein Superoxide Superoxide Dismutase tail the Spike Toxicity Viral particles water Water pollution [DOI] 10.1016/j.scitotenv.2022.153988 PMC 바로가기 [Article Type] Article
Shedding light on the toxicity of SARS-CoV-2-derived peptide in non-target COVID-19 organisms: A study involving inbred and outbred mice비표적 COVID-19 유기체에서 SARS-CoV-2 유래 펩타이드의 독성에 대한 조명: 근친교배 및 근친교배 마우스를 대상으로 한 연구Article Published on 2022-05-012022-09-11 Journal: Neurotoxicology [Category] COVID19(2023년), MERS, SARS, 바이오마커, 유전자 메커니즘, [키워드] acetylcholinesterase activated administration alteration animals antidepressant antioxidant anxiolytic applied biochemical Biomarker Brain C57Bl/6 J mice catalase consequence COVID-19 demonstrated depressive dismutase dispersion Effect Environmental Toxicology evaluate evaluated Evidence evidence of exposure to Field test genetic profile greater homeostasis hydrogen hydrogen peroxide Impact Laboratory locomotor maintain male mammalian mechanism memory memory deficit mice natural environments open oxidative stress Pandemic COVID-19 PCA peptide Principal component principal component analysis Protein Proteins provide reactive reduction in Research response SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 particle SARS-CoV-2 particles sensitivity shedding Spike protein Superoxide Superoxide Dismutase Swiss mice. the Spike the vaccine Therapeutic strategies therapeutic strategy Toxicity Viral [DOI] 10.1016/j.neuro.2022.03.012 PMC 바로가기 [Article Type] Article
Total antioxidant capacity as a marker of severity of COVID-19 infection: Possible prognostic and therapeutic clinical applicationCOVID-19 감염의 중증도 마커로서의 총 항산화 용량 : 가능한 예후 및 치료 임상 적용Article Published on 2022-04-012022-08-31 Journal: Journal of medical virology [Category] 바이오마커, [키워드] activity antioxidant antioxidant enzyme blood sample Blood samples catalase causative pathogen collected Concentration control group COVID-19 COVID-19 infection COVID-19 pandemic COVID-19 patient COVID-19 patients COVID-19 severity Defense dismutase Enzymes healthy individual healthy individuals healthy volunteer infected individual infected individuals Infection investigated marker Mild Mild disease nitric oxide oxidative stress Pathogenesis pathogenesis of SARS-CoV-2 Patient patients with COVID-19 Predictive prognostic Research SARS-COV-2 infection sera serum serum levels severe disease severely ill patients severity of COVID-19 statistically significant Superoxide Superoxide Dismutase susceptible TAC therapeutic Total total antioxidant capacity Variation was performed were measured with mild disease [DOI] 10.1002/jmv.27500 PMC 바로가기 [Article Type] Article
Are the Follicular Fluid Characteristics of Recovered Coronavirus Disease 2019 Patients Different From Those of Vaccinated Women Approaching in vitro Fertilization?Physiology Published on 2022-02-222022-10-31 Journal: Frontiers in Physiology [Category] COVID-19, [키워드] Ala Analysis anti SARS-CoV-2 immunoglobulins antibody carried collected Combination control group coronavirus disease Covid patients COVID-19 dismutase evaluate FIVE Follicular fluid healthy healthy controls in vitro induce inflammatory proteins interleukin-6 Lipid metabolic effect metabolite metabolomic analysis metabolomics Necrosis nine NMR NMR spectroscopy Oocyte outcome participant pilot study Pro proinflammatory markers radical scavenger recovered recovered COVID-19 patient Recovered COVID-19 patients SARS-CoV-2 SARS-COV-2 infection selected significantly lower TNF-α TNFα trimethylamine vaccination was performed western blotting analysis women [DOI] 10.3389/fphys.2022.840109 PMC 바로가기 [Article Type] Physiology
Post-mortem Findings of Inflammatory Cells and the Association of 4-Hydroxynonenal with Systemic Vascular and Oxidative Stress in Lethal COVID-19 †염증 세포의 부검 결과 및 치명적인 코로나19에서 4-하이드록시노넨알과 전신 혈관 및 산화 스트레스의 연관성 †Article Published on 2022-01-272022-09-11 Journal: Cells [Category] 바이오마커, 진단, [키워드] 4-hydroxynonenal 4-hydroxynonenal (4-HNE) absence acute tubular necrosis affected alveolar damage analyzed astrocytes Autopsy Biomarker Biomarkers blood vessel blood vessels Brain cells COVID-19 detrimental died differential expression Diffuse alveolar damage dismutase edema edematous finding Granulocytes immune system Immunohistochemical analysis Infection inflammatory cell inflammatory cells inflammatory parameters kidneys lethal leukocyte lipid peroxidation lung Lungs mitochondrial MPO myeloperoxidase nine organ organs oxidative burst oxidative stress Patient reactive reactive oxygen species (ROS) SAR-CoV-2 SARS-COV-2 infection SARS-CoV-2 virus Sepsis SOD2 Stress suggested Superoxide Superoxide Dismutase superoxide dismutase (SOD) survivor systemic the cells tissue Tubular Necrosis Vascular vascular stress [DOI] 10.3390/cells11030444 PMC 바로가기 [Article Type] Article
COVID-19 during Gestation: Maternal Implications of Evoked Oxidative Stress and Iron Metabolism ImpairmentArticle Published on 2022-01-182022-10-28 Journal: The Cochrane database of systematic reviews [Category] COVID-19, [키워드] Affect Alter antioxidant antioxidant system catalase cells complications consequence COVID-19 COVID-19 group COVID-19 infection dismutase Effect explain expression ferritin fetal group Health increase in iron Maternal mechanism metabolism negative influence no difference outcome oxidative stress oxygen supply pandemic pathogenic Placenta placental Pregnancy pregnant women proportion Proteins reached Research Result serum was recorded were recorded women [DOI] 10.3390/antiox11020184 PMC 바로가기 [Article Type] Article
Association Between Plasma Redox State/Mitochondria Function and a Flu-Like Syndrome/COVID-19 in the Elderly Admitted to a Long-Term Care UnitPhysiology Published on 2021-12-152022-10-31 Journal: Frontiers in Physiology [Category] COVID-19, [키워드] aging antioxidants association blood sample Care Cell Clinical data clinical implication clinical variable collected correlated Correlation analysis COVID-19 diagnosis of COVID-19 dismutase Effect elderly evidenced examined flu-like syndrome function highlight in vitro information LTC management material Mitochondria Mitochondrial function mitochondrial membrane potential moderate outcomes oxidative stress Patient plasma reactive reactive oxygen specy redox redox state ROS Symptom umbilical unit vascular endothelial cell viability viral infections was reduced were used [DOI] 10.3389/fphys.2021.707587 PMC 바로가기 [Article Type] Physiology