Development of prevalence and incidence of non-tuberculous mycobacteria in German laboratories from 2016 to 2020Research Article Published on 2023-12-062024-09-05 Journal: Emerging Microbes & Infections [Category] update2024, [키워드] drug susceptibility incidence Non-tuberculous mycobacteria NTM-pulmonary disease Prevalence [DOI] 10.1080/22221751.2023.2276342 PMC 바로가기 [Article Type] Research Article
Clinical Evaluation of the XDR-LFC Assay for the Molecular Detection of Isoniazid, Rifampin, Fluoroquinolone, Kanamycin, Capreomycin, and Amikacin Drug Resistance in a Prospective CohortMycobacteriology and Aerobic Actinomycetes Published on 2023-02-092024-09-05 Journal: Journal of Clinical Microbiology [Category] update2024, [키워드] Amikacin Capreomycin drug susceptibility drug-resistant tuberculosis Fluoroquinolone isoniazid kanamycin lateral-flow cell Mycobacterium tuberculosis rifampin [DOI] 10.1128/jcm.01478-22 PMC 바로가기 [Article Type] Mycobacteriology and Aerobic Actinomycetes
Rapid Identification of Drug Resistance and Phylogeny in M. tuberculosis, Directly from Sputum SamplesArticle Published on 2022-10-262022-11-15 Journal: Microbiology Spectrum [Category] 바이오마커, 변종, 치료제, [키워드] Accuracy applied approaches clinical sample clinician Complete COVID-19 pandemic Culture deaths described detect Diagnosis diagnostic test disease drug drug resistance drug susceptibility drugs effective Establishing evaluate evaluated faster genetic marker Genetic variant genetics genomic variant helping identification identify infecting Infectious disease information initial Initially molecular molecular test Mutation Mycobacterium Mycobacterium tuberculosis negatively affected Next-generation sequencing NGS phenotypic Phylogenetic phylogenetically Phylogeny protocol Rapid reducing reliability reported resistance responsible resulting Sample sequenced Sequencing sputum Sputum sample sputum samples Stage strain targeted sequencing TB patient the WHO Treatment Tuberculosis was used WGS WHO [DOI] 10.1128/spectrum.01252-22 PMC 바로가기
Inhaled therapy for COVID-19: Considerations of drugs, formulations and devicesCOVID-19에 대한 흡입 요법: 약물, 제형 및 장치에 대한 고려 사항Review Published on 2022-08-252022-09-11 Journal: International journal of pharmaceutics [Category] COVID19(2023년), SARS, 변종, 신약개발, 치료제, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus Administered administration anti-SARS-CoV-2 antiviral drug antiviral drugs Antiviral treatment approach Clinical studies Combinational Concentration coronavirus COVID-19 COVID-19 pandemic Device disease dose drug drug combination drug susceptibility drugs effective effective vaccine Efficacy etiological agent include Infection inhalation Inhaled intravenous key consideration limitations lower dose lung majority mono potency preclinical studies reduce reduced responsible SARS-CoV-2 SARS-CoV-2 variant SARS-CoV-2 variants severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 shown Side effects tested therapy Treatment treatment for COVID-19 [DOI] 10.1016/j.ijpharm.2022.122042 PMC 바로가기 [Article Type] Review
Characterization of the tenofovir resistance-associated mutations in the hepatitis B virus isolates across genotypes A to DArticle Published on 2022-07-012023-06-13 Journal: Antiviral Research [Category] B형 간염, [키워드] drug susceptibility Hepatitis B virus (HBV) Infectivity replication capacity Resistance-associated mutations (RAMs) tenofovir [DOI] 10.1016/j.antiviral.2022.105348
Impact of Short-Term Storage on Ex Vivo Antimalarial Susceptibilities of Fresh Ugandan Plasmodium falciparum IsolatesArticle Published on 2022-04-192024-08-28 Journal: Med Instrum [Category] 말라리아, [키워드] Antimalarials cold storage drug susceptibility Ex vivo growth malaria Plasmodium falciparum Uganda
Impact of COVID-19 pandemic on TB prevention and care in Addis Ababa, Ethiopia: a retrospective database studyCOVID-19 대유행이 에티오피아 아디스아바바의 결핵 예방 및 치료에 미치는 영향: 후향적 데이터베이스 연구Article Published on 2022-02-082022-09-11 Journal: BMJ Open [Category] COVID19(2023년), SARS, 치료기술, [키워드] Care Community community health Comparative analysis country COVID-19 COVID-19 pandemic database detection rate diagnostic diagnostic services drug susceptibility dysfunction Epidemiology ERAS evaluate evaluated Health health information Health information system health worker highlight Impact incidence rate Infection Information System isoniazid isoniazid prophylaxis mitigate morbidity performed Poisson regression Prevention and control quarter retrospective Retrospective study rifampicin therapy Treatment Tuberculosis was recorded [DOI] 10.1136/bmjopen-2021-053290 PMC 바로가기 [Article Type] Article
Ex vivo susceptibility to new antimalarial agents differs among human-infecting Plasmodium speciesarticle Published on 2021-12-312024-09-01 Journal: International Journal for Parasitology: Drugs and Drug Resistance [Category] 말라리아, [키워드] drug susceptibility Ex vivo Plasmodium falciparum Plasmodium knowlesi [Article Type] article
Susceptibility of widely diverse influenza a viruses to PB2 polymerase inhibitor pimodivirArticle Published on 2021-04-012023-06-14 Journal: Antiviral Research [Category] Fulltext, 신종인플루엔자, [키워드] drug susceptibility H7N9 Pandemic potential PB2 inhibitor pimodivir zoonotic influenza [DOI] 10.1016/j.antiviral.2021.105035 PMC 바로가기
Pleiotropy and epistasis within and between signaling pathways defines the genetic architecture of fungal virulence신호 전달 경로 내 및 사이의 다면발광 및 상위성은 진균 독성의 유전적 구조를 정의합니다Research Article Published on 2021-01-252022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] Affect amphotericin B Analysis antifungal drug resistance approach Author avirulent body temperature CAMP cascade Cell Cell signaling cellular cellular response Cellular responses characterization Combination complex component contribute cross Cryptococcal disease Cryptococcus cyclic AMP disease drug susceptibility drugs ENCODE epistatic interaction Europe Extracellular fungal Genes Genetic genetic architecture genetic difference genetic differences Genetic variation glycerol growth highlight human body Infection information isolate kinase Lineage locus make up mapping microbial modify molecular nucleotide osmolarity osmotic oxidative oxidative stress oxidative stress resistance pathogen pathogenicity Pathogens pathway phenotypic phenotypic variation physiological response pleiotropic polysaccharide capsule progeny promote protein kinase QTL Quantitative quantitative trait locus regulate regulator sensitivity Signal transduction Signaling signaling pathway strain Strains Stress temperate climates thought Tolerance traits underlie Variation virulence virulent [DOI] 10.1371/journal.pgen.1009313 PMC 바로가기 [Article Type] Research Article