Newly developed artificial intelligence algorithm for COVID-19 pneumonia: utility of quantitative CT texture analysis for prediction of favipiravir treatment effectRandomized Controlled Trial Published on 2022-08-012022-10-04 Journal: Japanese journal of radiology [Category] COVID19(2023년), SARS, 임상, [키워드] Accuracy Algorithm Analysis calculated Chest CT consolidation correlation COVID-19 COVID-19 patient COVID-19 patients CT CT finding determine disease onset disease severity duration of fever early treatment group emphysema Enrollment evaluated Favipiravir GGO ground-glass opacity initial late treatment group machine machine learning material Multicenter trial Open-label outcome Patient percentage performed Quantitative Randomized regression analysis scored significantly higher study participation the Kaplan-Meier method therapy Treatment utility viral clearance Volume [DOI] 10.1007/s11604-022-01270-5 PMC 바로가기 [Article Type] Randomized Controlled Trial
Short-chain fatty acid acetate triggers antiviral response mediated by RIG-I in cells from infants with respiratory syncytial virus bronchiolitis짧은 사슬 지방산 아세테이트는 호흡기 세포융합 바이러스 세기관지염이 있는 유아의 세포에서 RIG-I에 의해 매개되는 항바이러스 반응을 유발합니다Article Published on 2022-03-012022-09-11 Journal: EBioMedicine [Category] COVID19(2023년), SARS, 치료제, [키워드] A549 A549 cell A549 cells Acetate Admission animal animals antiviral response Bronchiolitis Cell clinical clinical isolates code COVID-19 demonstrated disease severity duration of fever Effect epithelial cell epithelial cells examined expression faster fatty fecal gut microbiota Hospitalized IFNB1 Impact in vitro Increased increased expression Infant Infants Infection interferon interferon-stimulated gene interferon-stimulated genes intranasally ISG ISG15 ISGs isolate isolates lung MAVS mice microbial modulation mouse model OAS1 oxygen oxygen saturation Patient PROTECT receptor reduce reduced reduction in respiratory respiratory cell respiratory epithelial cell respiratory epithelial cells respiratory syncytial virus RIG-I RSV SARS-CoV-2 infected patient SARS-CoV-2 infected patients severity significantly Stool strain Strains treated Treatment Trigger Viral load virus virus recognition [DOI] 10.1016/j.ebiom.2022.103891 PMC 바로가기 [Article Type] Article
Post-SARS-CoV-2 Acute Telogen Effluvium: An Expected ComplicationArticle Published on 2022-02-242022-10-30 Journal: Journal of Clinical Medicine [Category] COVID-19, [키워드] alopecia association average Case report causal link Characteristics Complication conducted COVID-19 COVID-19 patients cross-sectional described diagnosis of SARS-CoV-2 discharged duration of fever evaluated feature first symptom Hospitalization impair individuals Infection Laboratory male occur participant Patient patients Pneumonia Post-infection Prevalence Quality of life SARS-CoV-2 Sex significant difference single medical center Telogen telogen effluvium Treatment was performed [DOI] 10.3390/jcm11051234 PMC 바로가기 [Article Type] Article
Evaluation of minocycline combined with favipiravir therapy in coronavirus disease 2019 patients: A case-series study코로나바이러스 질환 2019 환자에서 파비피라비르 요법과 결합된 미노사이클린의 평가: 사례 시리즈 연구Article Published on 2022-01-012022-09-11 Journal: Journal of infection and chemotherapy : official j [Category] SARS, 치료제, [키워드] acute respiratory syndrome adverse event anti-inflammatory activity antibacterial activity Antiviral Chain Reaction changes in chemokine combination therapy Control control group coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 cytokine cytokine and chemokine production Cytokines duration of fever duration of hospitalization Efficacy and safety Endpoint evaluated Favipiravir greater groups hospital Inflammatory cytokines interleukin interleukin-6 interleukin-8 Japan MIN Minocycline monotherapy Negative PCR no difference Patient PCR test polymerase chain polymerase chain reaction reduction reported Retrospective study SARS-CoV-2 severe acute respiratory syndrome Coronavirus Severe case severe cases significantly significantly shorter Support therapy Treatment treatment initiation [DOI] 10.1016/j.jiac.2021.09.016 PMC 바로가기 [Article Type] Article
Clinical progression of patients with COVID-19 in Lagos State, NigeriaResearch Published on 2021-09-042022-10-29 Journal: Translational Medicine Communications [Category] COVID-19, [키워드] adhere Admission age antiviral medicine average Care clearance clinical clinical progression confidential interval confirmed COVID-19 case cough COVID-19 COVID-19 patients COVID-19 research Deterioration Dexamethasone duration of fever enrolled Epidemiology female ICU ICU patient Infection intensive care unit Lago Lagos majority male median Mortality NCDC Nigeria non-ICU patient occurred onset of symptoms Patient patients patients with COVID-19 progression radiological radiological improvement reduce Result reverse transcriptase PCR risk SARS-CoV-2 spread of COVID-19 state supplementary oxygen Support Symptom Symptomatic patients test negative the median Treatment upper respiratory tract virus were given [DOI] 10.1186/s41231-021-00099-w PMC 바로가기 [Article Type] Research
Characteristics and outcomes of family-practice patients with coronavirus disease 2019: a case seriesResearch Article Published on 2021-07-202022-10-30 Journal: Journal of Medical Case Reports [Category] COVID-19, SARS, [키워드] acute phase age average Care case sery center characterized Charlson Comorbidity Index clinical evaluation clinical history Community Medicine comorbid conditions Contact Contact tracing Control coronavirus disease criteria Department diagnostic duration of fever Emergency engage Epidemiology family Family medicine General practice had no Health hospital Hospitalized implementation IMPROVE interquartile range measure median Medicine outcome pandemic Patient physician polymerase chain positive prevention primary care reduce reported Result SARS-CoV-2 Spread subsequent supplementary material symptom onset symptomatic tested [DOI] 10.1186/s13256-021-02963-7 PMC 바로가기 [Article Type] Research Article
Association of Clinical and Immunological Characteristics With Disease Severity and Outcomes in 211 Patients With COVID-19 in Wuhan, ChinaCellular and Infection Microbiology Published on 2021-05-282022-10-31 Journal: Frontiers in Cellular and Infection Microbiology [Category] COVID-19, MERS, SARS, [키워드] Admission age Analysis B cells body temperature CD4+ T cells CD8+ T cell changes in clinical Clinical characteristics Clinical outcome clinician Comorbidities Comorbidity Coronavirus disease 2019 COVID-19 COVID-19 patients CREA creatinine Critical disease deterioration Disease progression disease severity duration of fever effective intervention expression feature functions global public health higher risk Hospital stay identify IL-6 immunological immunological characteristics indicated information Laboratory liver Logistic lymphocyte lymphocyte counts lymphopenia Male sex median age non-severe cases non-severe patient non-severe patients Older age Patient patients with COVID-19 peripheral lymphocyte predominant presenting progression recruited renal Result risk risk factor selective serum Serum level Severe case severe cases Severe patient severe patients significantly subpopulations subset sustained fever Symptom university WBC White blood cell with COVID-19 Wuhan Wuhan, China [DOI] 10.3389/fcimb.2021.667487 PMC 바로가기 [Article Type] Cellular and Infection Microbiology
National early warning score on admission as risk factor for invasive mechanical ventilation in COVID-19 patients: A STROBE-compliant studyCOVID-19 환자의 침습적 기계 환기에 대한 위험 요인으로 입원에 대한 국가 조기 경고 점수: STROBE 준수 연구Observational Study Published on 2021-05-142022-09-11 Journal: Medicine [Category] SARS, 임상, 치료제, [키워드] Admission aggravation assist Clinical data clinician Cohort Complication coronavirus disease COVID-19 cut-off value Demographic and clinical data develop duration of fever Early warning score evaluated Factor Fever global pandemic hospital indicated Inpatient Invasive mechanical ventilation Lactate lactate dehydrogenase LDH Logistic regression analysis management mechanical ventilation multivariate multivariate logistic regression analysis National National Early Warning Score NEWS Patient patient population patients with COVID-19 Prevent required respiratory symptom respiratory symptoms Retrospective study risk factor sensitivity severe respiratory symptoms significantly specificity Ventilation with COVID-19 [DOI] 10.1097/MD.0000000000025917 PMC 바로가기 [Article Type] Observational Study
Effect and safety of Chinese herbal medicine granules in patients with severe coronavirus disease 2019 in Wuhan, China: a retrospective, single-center study with propensity score matching2019년 중국 우한에서 발생한 중증 코로나바이러스 질환 환자에서 한약 과립의 효과 및 안전성: 성향 점수 매칭을 통한 후향적 단일 센터 연구Article Published on 2021-05-012022-08-31 Journal: Phytomedicine : international journal of phytother [Category] 치료제, [키워드] 1:1 28-day mortality baseline category caused Chinese Chinese herbal medicine CHM Clinical improvement Computerized tomography coronavirus disease Coronavirus disease 2019 cough COVID-19 D-dimer level Day defined duration of fever Dyspnea Effect Fever fibrinolysis Granule granules Health herbal medicine high risk hospital lung lung lesion male no significant difference Ordinal Scale Patient patients treated Primary outcome propensity score matching PSM reduced retrospective Retrospective study severe coronavirus disease severe COVID-19 significant difference single-center single-center study the patient Treatment treatment effect usual care usual care alone was used Wuhan [DOI] 10.1016/j.phymed.2020.153404 PMC 바로가기 [Article Type] Article
Efficacy evaluation of intravenous immunoglobulin in non-severe patients with COVID-19: A retrospective cohort study based on propensity score matching중증이 아닌 코로나19 환자에서 정맥주사 면역글로불린의 효능 평가: 성향 점수 매칭을 기반으로 한 후향적 코호트 연구Article Published on 2021-04-012022-09-12 Journal: International Journal of Infectious Diseases [Category] MERS, SARS, 진단, [키워드] absence acute respiratory syndrome antiviral therapy baseline characteristics benefit control group coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 died disease duration of fever effective Efficacy Efficacy evaluation enrolled Hospital stay Intravenous immunoglobulin median Mortality mortality rates non-severe patient outcome Patient progressed propensity score matching PSM retrospective cohort study Retrospective study secondary severe acute respiratory syndrome coronavirus 2 severe disease severity Standard therapy statistically significant difference therapy use of antibiotics virus clearance with COVID-19 [DOI] 10.1016/j.ijid.2021.01.009 PMC 바로가기 [Article Type] Article