A novel, accurate, and non-invasive liquid biopsy test to measure cellular immune responses as a tool to diagnose early-stage lung cancer: a clinical trials studyarticle Published on 2023-02-142024-09-05 Journal: Respiratory Research [Category] update2024, [키워드] Biomarker early stage Immune cells metabolism liquid biopsy Tumor associated antigens [DOI] 10.1186/s12931-023-02358-w PMC 바로가기 [Article Type] article
Spatiotemporal pattern recognition and dynamical analysis of COVID-19 in Shanghai, ChinaArticle Published on 2022-12-072022-11-15 Journal: Journal of theoretical biology [Category] COVID19(2023년), SARS, 변종, 치료기술, [키워드] Analysis Autocorrelation analysis China COVID-19 COVID-19 disease Daily Daily reproduction number diffusion disease dissemination dynamic Dynamic model early stage Effect hotspot IMPROVE mutant omicron outbreak provided retrospective SARS-CoV-2 transmission Shanghai Spatial statistics. spatiotemporal statistical suffered suppress the epidemic [DOI] 10.1016/j.jtbi.2022.111279 PMC 바로가기
Statistical analysis supports UTR (untranslated region) deletion theory in SARS-CoV-2Article Published on 2022-12-012022-11-16 Journal: Virulence [Category] COVID19(2023년), SARS, 변종, [키워드] affected Analysis ancestor Asymptomatic asymptomatic patients clinical outcomes correlation Degradation deletion of the untranslated region demonstrated Deterioration driving early stage evaluate Evolution explain genetic influence Genome hospitalized patient indicated mathematical Mortality mortality rate Mutation nucleic acid nucleic acid degradation system Patient SARS-CoV-2 SARS-COV-2 infection significantly significantly more similarity strain Support Symptoms the epidemic Toxicity UTR viral genome viral toxicity viral toxicity. virulence virus virus genome was performed [DOI] 10.1080/21505594.2022.2132059 PMC 바로가기
The impact of COVID-19 non-pharmaceutical interventions on HIV care continuum in China: An interrupted time series analysisResearch article Published on 2022-12-012022-10-05 Journal: The Lancet Regional Health - Western Pacific [Category] 변종, [키워드] 95% CI affected Analysis Antiretroviral therapy ART Care CD4 count CD4 counts CD4+ T cell China collected continuum COVID-19 decrease diagnose diagnoses Diagnosis disease early stage effort evaluate expected finding foundation funding HIV hospital implementation increase in Infectious disease Interrupted time series analysis interval Intervention maintain majority male median time natural non-pharmaceutical interventions (NPIs) NPI NPIs occurred outcome outcomes Poisson Prophylaxis public health emergency reached Region Regression model Science study period time interval time intervals Transmission were recorded [DOI] 10.1016/j.lanwpc.2022.100569 [Article Type] Research article
SARS-CoV-2 reinfection and COVID-19 severitySARS-CoV-2 재감염 및 COVID-19 심각성Article Published on 2022-12-012022-09-11 Journal: Emerging Microbes & Infections [Category] COVID19(2023년), SARS, 변종, [키워드] antibodies antibody clinical recovery clinical symptom Clinical symptoms coronavirus COVID-19 COVID-19 severity diagnosed early stage episode of Frequency Hospitalization ICU Infection infections negative RT-PCR no difference no differences Patient patients patients with SARS-CoV-2 performed positive positive RT-PCR Reinfection RT-PCR SARS-CoV-2 SARS-CoV-2 positive RT-PCR serology Seven severity Severity of infection transfer variant was performed were infected Whole genome sequencing [DOI] 10.1080/22221751.2022.2052358 PMC 바로가기 [Article Type] Article
Current trends in COVID-19 diagnosis and its new variants in physiological fluids: Surface antigens, antibodies, nucleic acids, and RNA sequencingReview article Published on 2022-12-012022-10-05 Journal: TrAC Trends in Analytical Chemistry [Category] 바이오마커, 변종, 진단, 치료기술, [키워드] addressed antibodies antibody Antigen antigens Beta Biomarker biosensors Blood body fluid circulation clustered regularly interspaced short palindromic repeats COVID-19 COVID-19 diagnosis COVID-19 virus diagnosis CRISPR Critical current Delta Detection sensitivity diagnostic early stage ELISA enzyme-linked immunosorbent enzyme-linked immunosorbent assay Gamma Infection isothermal amplification lateral flow immunoassay LFIA limit Loop-mediated isothermal amplification microarray analysis Microarray assays Mutation nucleic acid nucleic acids omicron outbreak overcome palindromic repeat physiological provide Rapid reduce reverse transcriptase-polymerase chain reaction reverse transcription RNA sequencing RT-LAMP RT-PCR Saliva SARS-CoV-2 Semen specificity Spread surface Urine variant variants virus viruses [DOI] 10.1016/j.trac.2022.116750 [Article Type] Review article
Magnetic/fluorescent dual-modal lateral flow immunoassay based on multifunctional nanobeads for rapid and accurate SARS-CoV-2 nucleocapsid protein detectionArticle Published on 2022-11-152022-11-15 Journal: Analytica chimica acta [Category] COVID19(2023년), SARS, 치료기술, [키워드] Accuracy addition diagnose diagnosis of SARS-CoV-2 early stage effective Elasticity fluorescent Infection Lateral lateral flow immunoassay LFIA limit of detection Magnetic/fluorescent dual-modal multifunctional Multifunctional nanobeads PEI Protein Quantitative analysis resulting Saliva SARS-CoV-2 SARS-CoV-2 nucleocapsid SARS-CoV-2 nucleocapsid protein SARS-CoV-2 pandemic sensitivity [DOI] 10.1016/j.aca.2022.340486 PMC 바로가기
Geographical distribution of SARS-CoV-2 amino acids mutations and the concomitant evolution of seven distinct clades in non-human hostsArticle Published on 2022-11-012022-11-16 Journal: Zoonoses and Public Health [Category] COVID19(2023년), SARS, 변종, [키워드] Amino acid analysed Analysis antigenicity clade Combination country Denmark distribution early stage Efficacy epidemiological Evolution exhibiting GISAID globe Host human SARS-CoV-2 indicate Latvia Local moderate MOST Mutation mutations Netherlands Non-human Non-human hosts ORF10 ORF3a pandemic pathogenicity Proteome evolution raised SARS-CoV-2 SARS-CoV-2 variant sequence Seven Surveillance sustained the SARS-CoV-2 genome the vaccine Transmissibility transmissions USA variant viral evolution Viral transmission viral variant Whole-genome sequence zoonotic zoonotic transmission [DOI] 10.1111/zph.12971 PMC 바로가기
Epidemiological and clinical features of SARS-CoV-2 infection in children during the outbreak of Omicron variant in Shanghai, March 7-31, 2022Article Published on 2022-11-012022-11-16 Journal: Influenza and Other Respiratory Viruses [Category] SARS, 변종, [키워드] 95% confidence interval Asymptomatic calculated children clinical Clinical characteristics clinical feature collected Community confirmed cases cough COVID-19 COVID-19 case COVID-19 vaccination COVID-19 vaccine dissemination dose early stage eligible epidemiological febrile disease Fever hospital Infection interquartile range leukopenia Local median median interval offer omicron Omicron SARS-CoV-2 variant outbreak pediatric Pediatric case reduced Relative risk risk RRs SARS-CoV-2 SARS-COV-2 infection Seven Shanghai symptomatic case symptomatic infection Transmission model vaccination Vaccines variant [DOI] 10.1111/irv.13044 PMC 바로가기
Viral load may impact the diagnostic performance of nasal swabs in nucleic acid amplification test and quantitative antigen test for SARS-CoV-2 detectionArticle Published on 2022-11-012022-11-15 Journal: Journal of infection and chemotherapy : official j [Category] SARS, 치료기술, [키워드] amplification Antigen automated collected cycle threshold detect diagnostic early stage evaluated healthcare Measures NAAT nasal swab nasal swabs Nasopharyngeal swab nasopharyngeal swabs negative correlation nine NPs nucleic acid amplification nucleic acid amplification test patients with COVID-19 positive Quantitative Quantitative SARS-CoV-2 antigen test Respiratory Coronavirus SARS-CoV-2 SARS-CoV-2 antigen SARS-CoV-2 detection significantly significantly higher significantly lower symptom onset tested Viral load were used [DOI] 10.1016/j.jiac.2022.07.023 PMC 바로가기