Manipulation of host immune defenses by effector proteins delivered from multiple secretion systems of Salmonella and its application in vaccine researcharticle Published on 2023-04-302024-09-01 Journal: Frontiers in immunology [Category] 살모넬라증, [키워드] effector proteins host defenses Salmonella infections secretion systems vaccine research [Article Type] article
SARS-CoV-2/COVID-19 and its relationship with NOD2 and ubiquitinationReview article Published on 2022-05-012022-10-05 Journal: Clinical immunology (Orlando, Fla.) [Category] COVID19(2023년), SARS, 바이오마커, 변종, 치료제, [키워드] activate activation pathway Alter Autoimmune autoinflammatory disease binding Combination COVID-19 COVID-19 infection disease Diseases downstream effector proteins facilitate Factor Genetic Host immune system inflammatory process Interaction Mutation NOD2 Protein recruit SARS-CoV-2 Signaling syndrome UBA1 ubiquitination VEXAS syndrome viral infection Yao syndrome [DOI] 10.1016/j.clim.2022.109027 [Article Type] Review article
In Vivo Hematopoietic Stem Cell Gene Therapy for SARS-CoV2 Infection Using a Decoy Receptor유인 수용체를 사용한 SARS-CoV2 감염에 대한 생체 내 조혈 줄기 세포 유전자 치료Article Published on 2022-04-012022-09-11 Journal: Human gene therapy [Category] COVID19(2023년), SARS, 변종, [키워드] abundance Adenovirus adjust airway Antiviral antiviral efficacy approach approaches Bone marrow CD46 Cell creating cytokine cytokine production decoy decoy receptor diminishe dose effector proteins elements erythrocytes erythroid cells erythropoiesis example expressed expression Gene therapy hematopoietic Hematopoietic stem cell hematopoietic system in vivo in vivo HSC gene therapy. Infection Intervention Intravenous injection less lethal dose Lung pathology mice neutralizing capacity not affect performed Peripheral blood pilot study Prophylaxis reached receptor receptor protein reduced Regulatory resulting rhesus rhesus macaque sACE2 SARS-CoV2 SARS-CoV2 infection SARS-CoV2 vaccine SARS-CoV2 vaccines secreted shown significantly spleen STEM stem cell survived susceptible Symptoms therapy transcriptional transduced Vaccine variant Viremia while β-globin [DOI] 10.1089/hum.2021.295 PMC 바로가기 [Article Type] Article
Clash of the titans: interferons and SARS-CoV-2타이탄의 충돌: 인터페론과 SARS-CoV-2Article Published on 2021-12-012022-09-11 Journal: Trends in immunology [Category] SARS, 치료제, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 coronavirus Defense effector protein effector proteins highlight Innate immunity Interaction interferon interferon-stimulated genes interferons modulate nuance nuances question responses SARS-CoV-2 severe acute respiratory syndrome Coronavirus virus virus–host interaction. viruses [DOI] 10.1016/j.it.2021.10.009 PMC 바로가기 [Article Type] Article
Mechanisms adopted by Salmonella to colonize plant hostsarticle Published on 2021-10-312024-09-01 Journal: Food Microbiology [Category] 살모넬라증, [키워드] adaptation strategy Avoidance strategy effector proteins Salmonella Suppression strategy T3SS [Article Type] article
Mechanistic insights into COVID-19 by global analysis of the SARS-CoV-2 3CL pro substrate degradomeSARS-CoV-2 3CL pro 기질 분해에 대한 글로벌 분석을 통한 COVID-19에 대한 기계론적 통찰력Article Published on 2021-10-262022-09-12 Journal: Cell Reports [Category] MERS, SARS, 진단, 치료제, [키워드] 3CL pro accelerate active site structure amplify Analysis bind binding Cell cleavage cleavage sites consequence COVID-19 degradomics drug design effector effector proteins global analysis glycoprotein healthy human lung identify inactivation interactome kidney lung Lungs MAP4K5 molecular docking mRNA pathology pathway Post-mortem protease Proteases Protein proteomics SARS-CoV SARS-CoV-2 SARS-CoV-2 3CL(pro) SARS-CoV-2 main protease SARS-CoV-2 replication SARS-CoV-2-infected cells specificity spike subsite specificity substrate substrates substrates. supported target the SARS-CoV-2 Transcription translation [DOI] 10.1016/j.celrep.2021.109892 PMC 바로가기 [Article Type] Article
Systematic reconstruction of an effector-gene network reveals determinants of Salmonella cellular and tissue tropism효과기 유전자 네트워크의 체계적인 재구성이 살모넬라의 세포 및 조직 친화성 결정 요인을 밝혀냅니다.Article Published on 2021-10-132024-08-21 Journal: Cell Host & Microbe [Category] 살모넬라증, [키워드] Bacterial pathogenesis effector proteins Salmonella Typhimurium sifA sopD2 SPI-2 T3SS spv locus sseF sseG steA.
Actin Assembly around the Shigella-Containing Vacuole Promotes Successful Infection시겔라 포함 소포 주위의 액틴 조립은 성공적인 감염을 촉진한다.Article Published on 2020-05-122024-08-22 Journal: Cell Reports [Category] 세균성이질, [키워드] actin cytoskeleton Arp2/3 complex Cdc42 effector proteins host-pathogen interactions intracellular pathogens N-WASP N(ε) fatty acylation Shigella flexneri vacuolar rupture
Inhibition of the type III secretion system by syringaldehyde protects mice from Salmonella enterica serovar Typhimurium시링알데하이드에 의한 제3형 분비 시스템의 억제가 살모넬라 엔테리카 세로바르 타이피무리움으로부터 쥐를 보호한다.Original Article Published on 2019-05-082024-07-29 Journal: Journal of Cellular and Molecular Medicine [Category] 살모넬라증, [키워드] anti‐infection effector proteins Salmonella enterica serovar Typhimurium syringaldehyde type III secretion system [DOI] 10.1111/jcmm.14354 PMC 바로가기 [Article Type] Original Article
Regulation of Salmonella-host cell interactions via the ubiquitin systemarticle Published on 2018-01-312024-09-01 Journal: International Journal of Medical Microbiology [Category] 살모넬라증, [키워드] E3 ligases effector proteins Innate immunity intracellular pathogens Salmonella ubiquitin [Article Type] article