Updated vaccine protects against SARS-CoV-2 variants including Omicron (B.1.1.529) and prevents transmission in hamstersArticle Published on 2022-11-042022-11-15 Journal: Nature Communications [Category] SARS, 변종, 진단, 치료기술, [키워드] Antigen B.1.1.529 B.1.1.7 B.1.351 B.1.617.2 Beta block Community COVID-19 vaccine current Delta delta variant detectable Efficacy eliminating expressed Fever Gamma hamster immunization Lineage Lung pathology maintain Neutralizing antibody response omicron P.1 pandemic predominant Prevent PROTECT SARS-CoV-2 strains SARS-CoV-2 variant sequence Spread titre Transmission Vaccine variants variants of concern vectored vaccine virus VoC VOCs [DOI] 10.1038/s41467-022-34439-7 PMC 바로가기
Validation Study of a Direct Real-Time PCR Protocol for Detection of Monkeypox VirusArticle Published on 2022-11-012022-11-15 Journal: The Journal of molecular diagnostics : JMD [Category] 치료기술, [키워드] Accuracy approach coronavirus disease COVID-19 described detection develop Direct eliminating imperative IMPROVE International Laboratory Laboratory testing Monkeypox nucleic acid extraction outbreak pandemic PCR protocol public health emergency Real-time PCR reducing sensitivity The United States validation virus World Health Organization [DOI] 10.1016/j.jmoldx.2022.09.001 PMC 바로가기
Assessing the mechanism of citywide test-trace-isolate Zero-COVID policy and exit strategy of COVID-19 pandemicArticle Published on 2022-10-042022-11-15 Journal: Infectious Diseases of Poverty [Category] COVID19(2023년), SARS, 변종, 진단, 치료기술, [키워드] 95% confidence interval Assessing Asymptomatic benefit calibration China Citywide testing coefficient compartmental model Compliance conducted Contact tracing contagious contribute COVID case COVID-19 COVID-19 pandemic deaths Delta develop Effectiveness eliminating Evolution exit Exit strategy fatigue implementation infections Isolation Latin Measures mechanism new strain omicron outbreak Outbreaks Partial PRCC projection proportion public health question raised RANK Region resource resources sensitivity analysis supported Test-trace-isolate the epidemic the SARS-CoV-2 Transmission Transmission model vaccination variant Zero-COVID policy. [DOI] 10.1186/s40249-022-01030-7 PMC 바로가기
Untargeted saliva metabolomics by liquid chromatography-Mass spectrometry reveals markers of COVID-19 severityArticle Published on 2022-09-222022-11-15 Journal: PLoS ONE [Category] 바이오마커, 변종, [키워드] Amino acid amino acids analysed Analysis C-reactive protein Clinical diagnosis Clinical severity clinical suspicion Clinical tests collected COVID-19 COVID-19 diagnosis COVID-19 pandemic COVID-19 patient COVID-19 patients COVID-19 severity Diagnosis diagnostic Disease progression driver dysregulation eliminating expand exploratory feature Health hospital hospitalised patient likelihood marker metabolomics Metadata Non-invasive offer outcomes Patient patients peripheral oxygen saturation Prognosis progressed receiver operating characteristics recent Research reservoir respiratory rate resulting reveal RT-PCR testing Saliva saliva sample serum severity shown the disease Treatment Vaccine variants [DOI] 10.1371/journal.pone.0274967 PMC 바로가기
Developing dendritic cell for SARS-CoV-2 vaccine: Breakthrough in the pandemicArticle Published on 2022-09-062022-11-15 Journal: Frontiers in Immunology [Category] SARS, 치료기술, [키워드] activate administration antigen presenting cell booster Course dendritic dendritic cell dendritic cells Developing Diseases effective Effectiveness eliminating finding high mutation rate immune system Immunity Immunotherapy induce Infection pandemic pathogenesis of SARS-CoV-2 Prevent problems SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 vaccines T cell T cells the disease Vaccine vaccine approach vaccine candidate virus [DOI] 10.3389/fimmu.2022.989685 PMC 바로가기
Understanding the epigenetic mechanisms in SARS CoV-2 infection and potential therapeutic approachesSARS CoV-2 감염의 후성유전학적 기전과 잠재적인 치료적 접근의 이해Review Published on 2022-09-012022-09-11 Journal: Virus research [Category] COVID19(2023년), SARS, 변종, 유전자 메커니즘, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus Anti-viral immune response association build caused Community coronavirus COVID-19 disease severity DNA DNA methylation drug effective eliminating Epigenetic epigenetic regulator epigenetics Escalation Health highlight histone Histone modification host cell host cells immune immune responses Immunity Infection initial Interaction mechanism microRNA Modification Mortality pandemic Pathogenesis pathogenesis of SARS-CoV-2 reduced risk SARS CoV-2 SARS- CoV-2 SARS-CoV-2 SARS-COV-2 infection severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 severity subsequent the disease Therapeutic approach therapeutic intervention Therapies understanding variants of SARS-CoV-2 viral infection Virology [DOI] 10.1016/j.virusres.2022.198853 PMC 바로가기 [Article Type] Review
COVID salivary diagnostics: A comparative technical studyCOVID 타액 진단: 비교 기술 연구Article Published on 2022-09-012022-09-11 Journal: Journal of medical virology [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 assumption can be used Care Chain Reaction coronavirus coronavirus disease Coronavirus disease 2019 COVID COVID-19 Delta diagnostic diagnostics direct methods eliminating envelope golden standard heat heat-released RNA high accuracy indicate individuals infected individual infected individuals Intervention Isolation mass mass surveillance molecular molecular diagnostics Mouthwash nasopharyngeal Nasopharyngeal swab nasopharyngeal swabs noninvasive NPs Open reading frame open reading frame 1 open reading frame 1ab ORF1ab pandemic patients polymerase chain polymerase chain reaction promote remained reported respiratory restriction RNA RNA extraction robust RT-PCR Saliva salivary sampling SARS-CoV-2 sensitivity severe acute respiratory syndrome Coronavirus specificity Surveillance the patient Viral viral gene viral genes virus spread while widespread [DOI] 10.1002/jmv.27883 PMC 바로가기 [Article Type] Article
An improved Fuzzy based GWO algorithm for predicting the potential host receptor of COVID-19 infectionResearch article Published on 2022-08-012022-10-05 Journal: Computers in biology and medicine [Category] COVID19(2023년), SARS, 변종, [키워드] ACE2 ACE2 protein acute respiratory syndrome ADAM17 Affect affected Algorithm analyzed ASGR1 Asialoglycoprotein Basigin Bone marrow Brain caused CD147 Cell CLEC4M Cluster Clustering Coronavirus-2 COVID-19 COVID-19 infection cytoplasm Differential evolution algorithm disease disintegrin domain drug effective Effectiveness eliminating entry of SARS-CoV-2 enzyme Evolution population dynamics exploratory expresse expression profile EXT1 EXT2 EXT3 Factor fusing Fuzzy clustering G protein-coupled receptor genetic diversity GLCE Glucuronic acid GPR78 Grey Grey wolf optimizer help Host host cell host cell membrane host receptor humans hybridizing I, II identify identifying IHC immunohistochemistry individual Infection inhibiting Interaction intestine kidney KREMEN1 Kringle liver lung mechanism membrane protein Membrane proteins Mutation NDST2 neuropilin NRP1 operator pathogenesis of COVID-19 pathogenesis of SARS-CoV-2 pathogenicity protease Protein PVR receptor replication of SARS-CoV-2 SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 spike protein SARS-CoV-2 virus serine protease Seurat shown Single cell RNA sequencing data single-cell Spike protein spleen Spread therapeutic target TMPRSS2 toolkit transcriptionally transcriptomics transmembrane protein Transmission virus XYLT1 XYLT2 [DOI] 10.1016/j.compbiomed.2022.106050 [Article Type] Research article
Deep Learning-Based Networks for Detecting Anomalies in Chest X-Rays흉부 X선에서 이상 징후를 감지하기 위한 딥 러닝 기반 네트워크Article Published on 2022-07-232022-09-11 Journal: BioMed Research International [Category] COVID19(2023년), SARS, 치료기술, [키워드] Accuracy ad hoc anomalies Anomaly approach approaches Chest chest X-ray chest X-rays Classifier classifiers conditions Critical data set database deep deep learning demonstrated detect Diagnosis eliminating evaluated example imaging test investigated knowledge network Pathologies pathology performed Pneumonia popularity professional Radiological examinations Research starting tested transfer X-ray [DOI] 10.1155/2022/7833516 PMC 바로가기 [Article Type] Article
Correlation Analysis of Positive Therapy Based on High Content Image Analysis Technology on Posttraumatic Nerve Growth in Patients with COVID-19 in the Context of Intelligent Medical TreatmentRandomized Controlled Trial Published on 2022-07-192022-10-05 Journal: Contrast media & molecular imaging [Category] COVID19(2023년), SARS, 임상, [키워드] active treatment Anxiety content Context control group Coronavirus pneumonia correlation crown Depression Diseases disorder early recovery Effect eliminating emotional evaluated growth hospital Image incidence incidence rate introduced Isolation maintain Mental disorder negative emotions nerve novel Novel coronavirus observation Patient patients Pneumonia positive Posttraumatic Stress promote Psychological PTSD randomly divided reduced rehabilitation selected significantly technology therapy treated Treatment with COVID-19 Wuhan [DOI] 10.1155/2022/9165764 PMC 바로가기 [Article Type] Randomized Controlled Trial