Demographic, behavioural and occupational risk factors associated with SARS-CoV-2 infection in UK healthcare workers: a retrospective observational studyArticle Published on 2022-11-072022-11-15 Journal: BMJ Open [Category] SARS, 변종, 진단, [키워드] 95% CI Analysis assessment behavioural COVID-19 demographic Diseases effective enhanced enrolled Epidemiology Factor General population HCW HCWs Health healthcare Healthcare system healthcare worker higher risk highest hospital identify include Infection infection control investigated Logistic regression measure multivariate logistic regression Observational cohort study occupational Pandemics Personal protective equipment Physiotherapist positive PPE Public public health questionnaire Regression model Reporting Resilience retrospective risk risk factor risk reduction SARS-CoV-2 antibody SARS-COV-2 infection SARS-CoV-2 variant Selection Shrinkage social distancing social distancing measures stability sustained Vaccine variable was used Workplace [DOI] 10.1136/bmjopen-2022-063159 PMC 바로가기
Enhanced Label-Free Nanoplasmonic Cytokine Detection in SARS-CoV-2 Induced Inflammation Using Rationally Designed Peptide AptamerArticle Published on 2022-11-022022-11-15 Journal: ACS applied materials & interfaces [Category] COVID19(2023년), SARS, 치료기술, 치료제, [키워드] acute respiratory syndrome Analysis Antibody-derived peptide aptamer (ADPA) applied aptamer Biomarker coronavirus COVID-19 patients cytokine detection Detection limit Disease progression disorders enhanced IL-6 immune pathway Immune status immunoassay immunoassays in vitro induced Inflammation inflammatory status information interleukin 6 (IL-6 Interluekin-6 (IL-6) Interpretation limit of detection localized surface plasmon resonance (LSPR) magnitude nanoplasmonic immunoassay pandemic pathogenic inflammation Patient peptide Predictive profile Prognosis provide quantification Rapid SARS-CoV-2 serum serum cytokine severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) [DOI] 10.1021/acsami.2c14748 PMC 바로가기
Enhanced antibody responses in fully vaccinated individuals against pan-SARS-CoV-2 variants following Omicron breakthrough infectionArticle Published on 2022-10-182022-11-15 Journal: Cell Reports Medicine [Category] COVID19(2023년), SARS, 변종, 진단, [키워드] acute respiratory syndrome ancestral Antibody Response Breakthrough infection coronavirus Course COVID-19 infection creating cross-neutralization cytokine D614G dominant enhanced evade immune Immunity individual induce memory T cell mRNA mRNA vaccination mRNA vaccine neutralization Neutralizing activity neutralizing antibody Neutralizing antibody response Neutralizing antibody titer omicron Omicron BA.1 Omicron BA.2 producing PROTECT recovered patient respond SARS-CoV-2 SARS-CoV-2 variant SARS-CoV-2 variants serum T cell T cell immune response the spike protein vaccinated individual vaccination variant variants of concern virus [DOI] 10.1016/j.xcrm.2022.100764 PMC 바로가기
Enhanced immune responses following heterologous vaccination with self-amplifying RNA and mRNA COVID-19 vaccinesArticle Published on 2022-10-042022-11-15 Journal: PLoS Pathogens [Category] COVID19(2023년), SARS, 변종, 진단, [키워드] Activation antibody Antibody Response Antibody titre antigen exposure baseline benefit binding BNT162b2 boost CD4+ T cell CD8+ Cellular immune response clinical trial Course COVID-19 Delta dose ELISA ELISPOT enhanced global public health glycoprotein Heterologous highest humoral immune memory immune response immunological increase in individual majority marker median mRNA mRNA COVID-19 vaccine mRNA vaccination mRNA vaccine naïve natural infection neutralising antibody titre omicron participant Participants PCR proportion question receiving recruited response RNA SARS-CoV-2 vaccine second dose seroconverted significantly higher subject the SARS-CoV-2 titre vaccination Vaccination strategy Vaccine variants were measured wildtype [DOI] 10.1371/journal.ppat.1010885 PMC 바로가기
Human genetic basis of severe or critical illness in COVID-19Article Published on 2022-09-202022-11-16 Journal: Frontiers in Cellular and Infection Microbiology [Category] SARS, 유전자 메커니즘, [키워드] acute respiratory syndrome affecting association Asymptomatic base caused contribute coronavirus COVID-19 Critical Critical illness death determinant disease disease severity enhanced Enzymes Factor Genetic Genetic variation genetic. Host Human human leukocyte antigen immune component indicated Interaction Interleukins loci mild infection morbidity and mortality multi-organ dysfunction outcome Precision preventive measure Respiratory failure SARS-CoV-2 SARS-CoV-2 receptor Serine severity of COVID-19 Toll-like receptor transmembrane [DOI] 10.3389/fcimb.2022.963239 PMC 바로가기
A Glycosylated RBD Protein Induces Enhanced Neutralizing Antibodies against Omicron and Other Variants with Improved Protection against SARS-CoV-2 InfectionArticle Published on 2022-09-142022-11-15 Journal: Journal of Virology [Category] SARS, 변종, 진단, [키워드] Affect antibody production B.1.1.529 B.1.1.7 lineage B.1.351 B.1.427 B.1.429 B.1.617.2 Beta coronavirus COVID-19 COVID-19 vaccine Delta delta variant demonstrated develop disease severity domain effective effective vaccine Effectiveness Efficacy elicited enhanced enhanced protection epitope Epsilon Gamma global public health highlight human ACE2 immunized immunized mice immunodominant IMPROVE Improved improved neutralizing activity induce Lineage mice mutant mutated Mutation Neutralizing Neutralizing activity neutralizing antibody Neutralizing antibody titer Numerous omicron Omicron and other variants Other P.1 pandemic Prevent probe protection Protective Protein pseudotyped pseudovirus RBD RBD protein SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 spike protein SARS-CoV-2 strain SARS-CoV-2 variant SARS-CoV-2 variants shown significantly Strains subunit Subunit vaccine the receptor-binding domain threat Transmissibility Vaccine variant variants weight loss [DOI] 10.1128/jvi.00118-22 PMC 바로가기
Enhanced Infection Prevention Measures Including Universal N95 Usage and Daily Testing: The Impact on SARS-CoV-2 Transmission in Cohorted Hospital Cubicles Through Successive Delta and Omicron WavesArticle Published on 2022-09-142022-11-15 Journal: Clinical Infectious Diseases: An Official Publicat [Category] SARS, 진단, [키워드] Cubicle Daily Delta enhanced Impact Including measure omicron prevention SARS-CoV-2 Universal Usage Wave [DOI] 10.1093/cid/ciac320 PMC 바로가기
Measles incidence in South Africa: a six-year review, 2015-2020Article Published on 2022-08-302022-11-15 Journal: BMC Public Health [Category] 진단, [키워드] affected age confirmed cases country Coverage COVID-19 Decline defined Effectiveness effort Elimination enhanced Epidemiology excluded febrile FIVE incidence incidence rate less lockdown restrictions Measle meet molecular outbreak Outbreaks positive Rash receive Region required retrospective South South Africa specimen Surveillance surveillance data targets tested the vaccine vaccination Vaccine Vaccines WHO World Health Organization yielding [DOI] 10.1186/s12889-022-14069-w PMC 바로가기
Pasos Hacia La Salud II: study protocol for a randomized controlled trial of a theory- and technology-enhanced physical activity intervention for Latina women, compared to the original interventionPasos Hacia La Salud II: 원래 개입과 비교하여 라틴계 여성을 위한 이론 및 기술 강화 신체 활동 개입의 무작위 대조 시험을 위한 연구 프로토콜Article Published on 2022-08-012022-09-11 Journal: Trials [Category] 임상, [키워드] activity adaptation age approach ARMS assessments baseline baseline assessments benefit build change chronic disease Chronic diseases clinical Complete COVID-19 pandemic described dissemination Effect Efficacy eHealth enhanced equity exercise exploratory feature female greater Health health benefits Health promotion help helping Hispanic increased risk increases in intent-to-treat interactions Intervention intervention effect Intervention effects Latina linear long term maintain manuscript mHealth outcome participant physical activity physically Population proportion Randomized Randomized controlled trial recruited Regression model Research secondary outcome Self-efficacy Social support Study protocol Support technology treat website women [DOI] 10.1186/s13063-022-06575-4 PMC 바로가기 [Article Type] Article
Detecting COVID-19 patients via MLES-Net deep learning models from X-Ray imagesX-Ray 이미지에서 MLES-Net 딥 러닝 모델을 통해 COVID-19 환자 감지Article Published on 2022-07-302022-09-11 Journal: BMC Medical Imaging [Category] COVID19(2023년), SARS, 치료기술, [키워드] Accuracy Attention automatically average calculation categories category caused Characteristics chest X-ray Chest X-ray images Classifier classifiers Convolutional neural network convolutional neural network (CNN) Corona Coronavirus infection correlation COVID-19 COVID-19 patient cumulative death deep deep learning diagnose Diagnosis Dot product Efficiency enhanced experimental results Factor feature Final generate IMPROVE information initial Local Mask MLES-Net. multiple groups network network model normalized Novel coronavirus Novel coronavirus infection parameter parameters Pneumonia Prevent problems restored scaled sensation similarity Spread Variability virus Virus Disease was obtained [DOI] 10.1186/s12880-022-00861-y PMC 바로가기 [Article Type] Article