Enterocyte – Communicable Diseases Research

Clinical investigation of intestinal fatty acid-binding protein (I-FABP) as a biomarker of SARS-CoV-2 infection

SARS-CoV-2 감염의 바이오마커로서의 장지방산결합단백(I-FABP)의 임상적 조사

Article

Published on 2021-12-012022-09-11
Journal: International Journal of Infectious Diseases [Category] 바이오마커,

Expression of SARS‐CoV‐2 entry factors, electrolyte, and mineral transporters in different mouse intestinal epithelial cell types

Original Article

Published on 2021-11-092022-10-28
Journal: Physiological Reports [Category] COVID-19, MERS, SARS,

[키워드] abundantly expressed ACE2 Amino acid apical membrane AT1 basolateral calcium Cell cell type cells CFTR COVID‐19 diarrhea DRA Enterocyte enzyme epithelial cell type Evidence expressed expressing expression expression pattern Factor Factors goblet greater heterogeneous Hypothesis identity indicated infect Infection intestinal intestinal cell intestine iron mammalian mucosa multifunctional multifunctional protein pandemic Paneth cells protease provide receptor ACE2 required responsible SARS‐CoV‐2 SARS‐CoV‐2 infection SIT1 small intestine tested TMPRSS TMPRSS2 TMPRSS4 transmembrane Transport villus virus were expressed
[DOI] 10.14814/phy2.15061 PMC 바로가기 [Article Type] Original Article

Diosmectite inhibits the interaction between SARS-CoV-2 and human enterocytes by trapping viral particles, thereby preventing NF-kappaB activation and CXCL10 secretion

Article

Published on 2021-11-052022-10-29
Journal: Scientific Reports [Category] COVID-19, SARS,

[키워드] ACE2 ACE2 receptor Activation analyzed angiotensin-converting enzyme 2 anti-inflammatory property binding Caco-2 Caco-2 cell Cell cells component COVID-19 management protocols CXCL10 diarrhea Diosmectite domain downstream Effect Effects ELISA Enterocyte Evidence gastroenterology Gastrointestinal models gastrointestinal system heat-inactivated immunofluorescence Inflammation inhibit inhibited Interaction intestine limit management membranes nuclear Pathogenesis pathogenic patients Prevent public health RBD receptor SARS-CoV-2 secretion Spike protein Symptom tested the spike protein Trapping Treatment Viral particles viral spread virus
[DOI] 10.1038/s41598-021-01217-2 PMC 바로가기 [Article Type] Article

Molecular Insights into SARS-CoV2-Induced Alterations of the Gut/Brain Axis

장/뇌 축의 SARS-CoV2 유발 변형에 대한 분자적 통찰력

Article

Published on 2021-09-282022-09-12
Journal: International Journal of Molecular Sciences [Category] SARS, 진단,

[키워드] Absorption ACE2 alteration alterations Amino acid amino acids Analysis angiotensin axis Brain cells chronic infection co-expression coding cognitive COVID COVID-19 DDC develop disorder disorders dopa Dopamine Enterocyte enterocytes enzyme Express expression expression level extreme fatigue highest host receptor Inflammation insight Intestinal Organoids involved L-DOPA Long COVID long-lasting metabolic pathway metabolism monoamine oxidase Neuropsychiatric Neurotransmitters Neutral pathway Patient performed precursor precursors reported responsible RNA-seq data SARS-CoV2 small intestine Symptom tissue tissues trace amines
[DOI] 10.3390/ijms221910440 PMC 바로가기 [Article Type] Article

SPI2 T3SS effectors facilitate enterocyte apical to basolateral transmigration of Salmonella -containing vacuoles in vivo

SPI2 T3SS 효과기는 생체 내에서 Salmonella가 포함된 소포의 장세포 정단에서 기저측으로의 이동을 촉진합니다.

Article

Published on 2021-09-202024-07-29
Journal: Gut Microbes [Category] 살모넬라증,

[키워드] Salmonella pathogenicity island 2 (Spi-2) apical to basolateral transmigration Enterocyte mucosal translocation Salmonella
[DOI] 10.1080/19490976.2021.1973836 PMC 바로가기

HIV infection drives interferon signaling within intestinal SARS-CoV-2 target cells

Resource and Technical Advance

Published on 2021-08-232022-10-30
Journal: JCI Insight [Category] COVID-19, SARS,

[키워드] ACE2 ACE2 expression AIDS/HIV analyzed antiviral genes antiviral response canonical cause change chronic controls COVID-19 disease severity downregulation Enterocyte epithelial cell expression fatality GI Tract Gut highest HIV infection homeostasis impair increased risk individual individuals infect Innate immunity interferon response interferon signaling intestinal lymphoid mucosal Prevent Protein reduction SARS-CoV-2 SARS-CoV-2 entry receptor SARS-COV-2 infection SARS-CoV-2 nucleocapsid SARS-CoV-2 receptor single-cell small intestine Symptoms target cell target cells tissue TMPRSS2 TMPRSS4 transcriptional profile treated uninfected upregulation vaccine response
[DOI] 10.1172/jci.insight.148920 PMC 바로가기 [Article Type] Resource and Technical Advance

Differential susceptibility of SARS‐CoV‐2 in animals: Evidence of ACE2 host receptor distribution in companion animals, livestock and wildlife by immunohistochemical characterisation

동물에서 SARS-CoV-2의 감수성: 면역조직화학적 특성화에 의한 반려동물, 가축 및 야생동물에서 ACE2 숙주 수용체 분포의 증거

Original Article

Published on 2021-07-262022-09-10
Journal: Transboundary and emerging diseases [Category] COVID19(2023년), MERS, SARS, 치료기술,

[키워드] absence ACE2 ACE2 expression Acinonyx addition anatomical angiotensin angiotensin converting enzyme angiotensin converting enzyme 2 binding bronchiolar cats cattle characterisation cheetah coronavirus distribution Enterocyte enterocytes enzyme Eptesicus European badger Evidence evidence of felids Felis ferret ferrets gastrointestinal tracts histological Host host cell host cell membrane host receptor host susceptibility humans IHC immunohistochemistry in some indicated information intestine limit lion Lower respiratory tract lung Lungs Mesocricetus microvillus mink mustelids nasal nasal mucosa nasal turbinate Neovison Ovis primates Protein receptor respiratory respiratory and gastrointestinal tracts respiratory tract respiratory tracts SARS Coronavirus SARS coronaviruses SARS‐CoV‐2 SARS‐CoV‐2 infection SARS‐CoV‐2 serotine bat sheep species susceptibility tiger tissue tissue tropism Trachea Viral viral infection zoonoses
[DOI] 10.1111/tbed.14232 PMC 바로가기 [Article Type] Original Article

Exploring the Mystery of Angiotensin-Converting Enzyme II (ACE2) in the Battle against SARS-CoV-2

Review Article

Published on 2021-06-042022-10-31
Journal: Journal of the Renin-Angiotensin-Aldosterone Syste [Category] COVID-19, MERS, SARS,

[키워드] ACE inhibitors ACE2 ACE2 expression ACE2 receptor age Angiotensin receptor blockers Angiotensin-converting enzyme battle Betacoronavirus caused Cell cellular entry Cerebrovascular disease chronic obstructive clinical Colon Comorbidity COPD Coronary heart disease COVID-19 COVID-19 patient COVID-19 therapeutics diabetes Enterocyte expression Factor hypertension infect Infection inflammatory signaling knowledge management master regulator outcome pandemic pneumocyte positive primary site pulmonary disease regulated Regulation respiratory tract SARS-CoV-2 SARS-CoV-2 infections smoking the SARS-CoV-2 virus Trial Tuberculosis
[DOI] 10.1155/2021/9939929 PMC 바로가기 [Article Type] Review Article

Diarrhea due to SARS-CoV-2-Related Exocrine Pancreatic Insufficiency

Case Report

Published on 2021-05-212022-11-01
Journal: Case Reports in Gastrointestinal Medicine [Category] COVID-19,

B 0 AT1 Amino Acid Transporter Complexed With SARS-CoV-2 Receptor ACE2 Forms a Heterodimer Functional Unit: In Situ Conformation Using Radiation Inactivation Analysis

Original Research

Published on 2021-05-132022-10-31
Journal: Function (Oxford, England) [Category] COVID-19, SARS,

[키워드] 6M17 accompanied ACE2 acid Amino acid amino acid transporter angiotensin-converting enzyme-2 apical membrane approach AT1 B⁰AT1 coexpressed complex component conformation contribute COVID-19 COVID-19 patients dose Enterocyte expressed expression form functional Gut human tissues indicated Interaction intestine linear magnitude membrane membrane vesicle membranes mitigate molecular docking molecular weight Neutral neutral amino acid transport obligatory outbreak Particles persistence physiological purified Radiation radiation inactivation reported SARS-CoV-2 SARS-CoV-2 receptor small intestine sodium-dependent transport Symptom translational Transport transporter treat variant virion
[DOI] 10.1093/function/zqab027 PMC 바로가기 [Article Type] Original Research