enterocytes – Communicable Diseases Research

Autophagy-linked plasma and lysosomal membrane protein PLAC8 is a key host factor for SARS-CoV-2 entry into human cells

Article

Published on 2022-11-022022-11-15
Journal: The EMBO Journal [Category] COVID19(2023년), SARS, 진단,

The Entero-Mammary Pathway and Perinatal Transmission of Gut Microbiota and SARS-CoV-2

Article

Published on 2022-09-072022-11-16
Journal: International Journal of Molecular Sciences [Category] SARS, 치료기술,

[키워드] Actinobacteria analyzed Anti-inflammatory effects association Bacteria Bacterial characterized collected colostrum correlated COVID-19 Data analysis demonstrated DNA DNA sequencing enterocytes explain fecal fecal microbiota Firmicute Gut gut microbiota high-throughput DNA sequencing human colostrum increase infect Infection microbiota mother mother rectal swab nasopharyngeal neonate rectal swab. outcome outcomes overcome Perinatal positive Pregnancy pregnant women Proteobacteria provide rectal rectal swab rRNA RT-ddPCR RT-qPCR SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 RNA severe respiratory disease Spearman correlation analysis virus women
[DOI] 10.3390/ijms231810306 PMC 바로가기

Evidence of Infection of Human Embryonic Stem Cells by SARS-CoV-2

SARS-CoV-2에 의한 인간 배아 줄기 세포 감염의 증거

Article

Published on 2022-06-102022-09-11
Journal: Frontiers in Cellular and Infection Microbiology [Category] COVID19(2023년), SARS, 유전자 메커니즘, 치료기술, 치료법, 치료제,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 cell types coronavirus described differentially expressed dsRNA embryonic embryos enterocytes Evidence evidence of Gut hepatocytes hESC Human immunofluorescence microscopy infect Infection interferon-stimulated gene interferon-stimulated genes ISGs life cycle low expression mechanism neurons question replicate Replication replication of SARS-CoV-2 reported Respiratory system RNA S protein SARS-CoV-2 SARS-CoV-2 receptors severe acute respiratory syndrome Coronavirus significantly STEM stem cell supernatant supernatants Support syncytium threshold upregulated variety Viral RNA viral titer viral titers virion virus were infected
[DOI] 10.3389/fcimb.2022.911313 PMC 바로가기 [Article Type] Article

A New Butyrate Releaser Exerts a Protective Action against SARS-CoV-2 Infection in Human Intestine

새로운 부티레이트 방출제는 인간의 장에서 SARS-CoV-2 감염에 대한 보호 조치를 취합니다

Article

Published on 2022-01-272022-09-10
Journal: Molecules [Category] SARS, 유전자 메커니즘, 치료제,

[키워드] ACE2 Action Activation acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 administration alteration angiotensin angiotensin-converting enzyme-2 Antiviral antiviral response butyramide Butyrate carbamoyl Characteristics coronavirus COVID-19 Cytokines Defense defense mechanisms Diseases enterocytes enzyme expression FBA functional Gut gut microbiome Host Human IL-15 infected cells Infection Infectious diseases intestinal models investigated involved limit MCP-1 mechanism metabolite Microbiome modulate monocyte monocyte chemoattractant protein-1 neuropilin Neuropilin-1 New NF-kB NRP1 nuclear oral administration Pathways Patient presenting pro-inflammatory cytokine pro-inflammatory cytokines protease Protective receptor reduce reduced reducing regulate Releaser reported respiratory SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2-infected cells Serine serine 2 several gene several genes severe acute respiratory syndrome Coronavirus small intestinal biopsy small intestine TMPRSS2 TNF-α transmembrane transmembrane protease serine 2 up-regulation viral infection
[DOI] 10.3390/molecules27030862 PMC 바로가기 [Article Type] Article

GASTROINTESTINAL COMPLICATIONS OF CORONAVIRUS DISEASE (COVID-19)

Review Article

Published on 2021-12-172022-10-28
Journal: Arquivos Brasileiros de Cirurgia Digestiva : ABCD [Category] COVID-19, SARS,

[키워드] ACE2 acute respiratory syndrome addition alveolar epithelial cells Analysis angiotensin-converting enzyme 2 articles Atypical binding Case report Case series Case-control complications Coronavirus infections Coronavirus-2 COVID-19 death direct infection early diagnosis enterocytes gastrointestinal complication Gastrointestinal infection gastrointestinal tract greater Hemorragia hemorrhage Hemorrhagic heterogeneity high expression level Infecções por Coronavirus Infection Ischemia Isquemia manifestation Pancreatite Pancreatitis qualitative data receptor retrieved retrospective cohort SARS-CoV SARS-CoV-2 SciELO searched serious complication small intestine susceptibility susceptible target cell the disease thrombotic tissue Trato gastrointestinal Treatment vascular endothelial cells was performed
[DOI] 10.1590/0102-672020210002e1620 PMC 바로가기 [Article Type] Review Article

Clinical investigation of intestinal fatty acid-binding protein (I-FABP) as a biomarker of SARS-CoV-2 infection

SARS-CoV-2 감염의 바이오마커로서의 장지방산결합단백(I-FABP)의 임상적 조사

Article

Published on 2021-12-012022-09-11
Journal: International Journal of Infectious Diseases [Category] 바이오마커,

[키워드] Admission Biomarker Brazil C-reactive protein characteristic clinical Clinical characteristics collected Concentration correlation COVID-19 COVID-19 disease COVID-19 disease severity COVID-19 patient COVID-19 patients Critically ill Critically ill patient critically ill patients cytokine cytokine level cytokine levels Cytokines damage demonstrated disease severity enrolled Enterocyte enterocytes epithelial cells exacerbated exhibit fatty Fatty acid gastrointestinal tract Hospital stay hospitalisation IL-6 Illness severity infected patient infected patients Inflammation Inflammatory response interferon interleukin interleukin-6 intestinal intestinal epithelial cells intestinal epithelial cells. Laboratory laboratory findings lesion lesions less nonsurvivor nonsurvivors Patient plasma poor prognosis Prognosis Protein receiver operating characteristic receiver operating characteristic curve recorded SARS-CoV-2 SARS-COV-2 infection suggested Urine
[DOI] 10.1016/j.ijid.2021.09.051 PMC 바로가기 [Article Type] Article

Parechovirus A Infection of the Intestinal Epithelium: Differences Between Genotypes A1 and A3

Cellular and Infection Microbiology

Published on 2021-11-012022-10-31
Journal: Frontiers in Cellular and Infection Microbiology [Category] COVID-19,

Intestinal Protein Characterisation of SARS-CoV-2 Entry Molecules ACE2 and TMPRSS2 in Inflammatory Bowel Disease (IBD) and Fatal COVID-19 Infection

Original Article

Published on 2021-10-252022-10-30
Journal: Inflammation [Category] COVID-19, COVID19(2023년), MERS, SARS,

[키워드] ACE2 age analysed characterisation Colon colonic contribute controls coronavirus SARS-CoV-2 COVID-19 COVID-19 cohort Crohn’s disease Crohn’s disease cytoplasmic dataset enterocytes Evidence expressed expression fatal COVID-19 Frequency Gut gut biology histologic histology IBD ileal Immune cell immune response Inflammation Inflammatory bowel disease intestinal lamina propria Lungs membrane molecule morbidity and mortality mucosa Multiple myeloma no difference Patient Plasma cell Plasma cells Protein provide recent Regulatory SARS-CoV-2 SARS-COV-2 infection shown significantly higher staining staining intensity supplementary material tissue expression TMPRSS2 TMPRSS2 expression UC ulcerative colitis viral tropism widespread
[DOI] 10.1007/s10753-021-01567-z PMC 바로가기 [Article Type] Original Article

Molecular Insights into SARS-CoV2-Induced Alterations of the Gut/Brain Axis

장/뇌 축의 SARS-CoV2 유발 변형에 대한 분자적 통찰력

Article

Published on 2021-09-282022-09-12
Journal: International Journal of Molecular Sciences [Category] SARS, 진단,

[키워드] Absorption ACE2 alteration alterations Amino acid amino acids Analysis angiotensin axis Brain cells chronic infection co-expression coding cognitive COVID COVID-19 DDC develop disorder disorders dopa Dopamine Enterocyte enterocytes enzyme Express expression expression level extreme fatigue highest host receptor Inflammation insight Intestinal Organoids involved L-DOPA Long COVID long-lasting metabolic pathway metabolism monoamine oxidase Neuropsychiatric Neurotransmitters Neutral pathway Patient performed precursor precursors reported responsible RNA-seq data SARS-CoV2 small intestine Symptom tissue tissues trace amines
[DOI] 10.3390/ijms221910440 PMC 바로가기 [Article Type] Article

Role of intestinal extracellular matrix-related signaling in porcine epidemic diarrhea virus infection

Research Article

Published on 2021-09-132022-10-28
Journal: Virulence [Category] Coronavirus,

[키워드] activated activating antimicrobial peptide antiviral activity antiviral cytokine CD44 clinical Cluster cluster of differentiation 44 differentially expressed gene dysfunction ECM enterocytes epidemic diarrhea exhibited expression Extracellular Extracellular matrix Genes high mortality rate IL-11 IL-18 Infection Interaction intestinal intestinal epithelial cell intestinal tissue intestine investigated lesions mechanism network analysis nuclear Pathways PEDV Porcine epidemic diarrhea virus positive correlation potential therapeutic target progeny virion promote Replication resulting role serpin family E member 1 SERPINE1 Signaling significantly structural framework transcriptional level viral infection Viral load viral release viral replication virus virus infection
[DOI] 10.1080/21505594.2021.1972202 PMC 바로가기 [Article Type] Research Article