Nucleic Acid Vaccines Encoding Proteins and Virus-like Particles for HIV PreventionReview Published on 2024-03-122024-09-05 Journal: Vaccines [Category] update2024, [키워드] AIDS antibody bNAbs DNA Env Gag mRNA VLP [DOI] 10.3390/vaccines12030298 PMC 바로가기 [Article Type] Review
Construction of a Large Size Human Immunoglobulin Heavy Chain Variable (VH) Domain Library, Isolation and Characterization of Novel Human Antibody VH Domains Targeting PD-L1 and CD22대형 인간 면역글로불린 중쇄 가변(VH) 도메인 라이브러리의 구축, PD-L1 및 CD22를 표적으로 하는 신규 인간 항체 VH 도메인의 분리 및 특성화Article Published on 2022-04-062022-09-12 Journal: Frontiers in Immunology [Category] COVID19(2023년), SARS, 진단, [키워드] antibody antibody domain drug conjugations (DDC) antibody VH domains antigens approved CD22 CDR2 CDR3 chain characterization construction DDC domain Env example FLT3 grafting healthy donor HIV-1 Human in vitro information library library construction. mAb monoclonal antibody novel PD-L1 phage primer Protein provide RBD reagents targeting targets the SARS-CoV-2 therapy variable was obtained was used [DOI] 10.3389/fimmu.2022.869825 PMC 바로가기 [Article Type] Article
Syncytin, envelope protein of human endogenous retrovirus (HERV): no longer ‘fossil’ in human genomeReview Published on 2022-01-122022-10-28 Journal: Animal Cells and Systems [Category] COVID-19, [키워드] acute respiratory syndrome arising Cancer caused coding coronavirus COVID-19 COVID-19 disease developmental Diseases Env envelope protein Evolution exogenous retrovirus expressed HERV HERVs Human Human genome Infection mental symptoms molecular Neurodegenerative disease Neurological diseases Pathologies Placenta Proteins reported retroviral retrovirus SARS-CoV-2 similarity syncytin the spike protein transcript Viral particles [DOI] 10.1080/19768354.2021.2019109 PMC 바로가기 [Article Type] Review
Modification of the Spike Protein for Vaccines against Enveloped RNA VirusesReviews Published on 2021-08-262022-10-30 Journal: Molecular Biology [Category] COVID-19, [키워드] circulating Env enveloped RNA viruses evade feature form fusion mechanisms Haemagglutinin HIV-1 host cell membranes host immune responses induce Infection influenza A virus mechanism MOST Neutralizing antibodies neutralizing antibody overcome Protein RNA RNA virus SARS-CoV-2 Spike protein strain Surface glycoprotein surface protein the Spike Vaccine Vaccines Variability Viral antigen viral envelope viral surface [DOI] 10.1134/S0026893321030158 PMC 바로가기 [Article Type] Reviews
Evidence of the pathogenic HERV-W envelope expression in T lymphocytes in association with the respiratory outcome of COVID-19 patientsCOVID-19 환자의 호흡기 결과와 관련된 T 림프구의 병원성 HERV-W 외피 발현의 증거Article Published on 2021-04-012022-09-11 Journal: EBioMedicine [Category] Coronavirus, 바이오마커, 치료제, [키워드] activated acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 analysed Analysis association Biomarker Blood blood cell Blood cells blood sample Blood samples Clinical characteristics Clinical research Clinical signs coronavirus coronavirus disease Coronavirus disease 2019 correlated correlation COVID-19 COVID-19 patient COVID-19 patients cytokine expression cytokine levels Cytokine storm Disease progression Effects effort Env evaluate evaluated evidence of Exhaustion expressed expression feature flow cytometry healthy donor healthy donors HERV HERV-W. human endogenous retroviruses HERVs highlighting Hospitalization human endogenous retroviruses identify immunopathological Infection infectious agent infectious agents Inflammation Inflammatory marker inflammatory markers leukocyte leukocytes lymphocyte management manuscript marker outcome pathogenic Patient Patient management Pneumonia predict progression of disease promote Protein Quantitative recent finding recent findings reflect Research respiratory Respiratory outcome retrovirus reverse transcriptase reverse transcriptase PCR SARS-CoV-2 severe acute respiratory syndrome Coronavirus severity T lymphocyte T-cell differentiation T-cell exhaustion the disease Therapeutic approach therapeutic intervention [DOI] 10.1016/j.ebiom.2021.103341 PMC 바로가기 [Article Type] Article
Exaptation of Retroviral Syncytin for Development of Syncytialized Placenta, Its Limited Homology to the SARS-CoV-2 Spike Protein and Arguments against Disturbing Narrative in the Context of COVID-19 VaccinationReview Published on 2021-03-192022-10-28 Journal: Biology [Category] COVID-19, [키워드] Affect argument Cell cells coded Context COVID-19 COVID-19 vaccine development Env Evolution Exaptation exogenous retroviruses facilitate facilitated function fused generate glycoprotein Health host cell host cell membrane Human immune response Impact Interaction Limited mammalian mechanism mother narrative Newborn Placenta Pregnancy Protein required retroviral retrovirus S protein SARS-CoV-2 SARS-CoV-2 vaccine sequence similarity similarity simple spike Spike protein syncytin the SARS-CoV-2 unlikely uterine viral envelope virus [DOI] 10.3390/biology10030238 PMC 바로가기 [Article Type] Review