expression levels – Communicable Diseases Research

Functional profiling of Covid 19 vaccine candidate by flow virometry

Article

Published on 2022-09-012022-10-05
Journal: Vaccine [Category] SARS, 변종, 진단, 치료기술,

C1R, CCL2, and TNFRSF1A Genes in Coronavirus Disease-COVID-19 Pathway Serve as Novel Molecular Biomarkers of GBM Prognosis and Immune Infiltration

코로나바이러스 질병-COVID-19 경로의 C1R, CCL2 및 TNFRSF1A 유전자는 GBM 예후 및 면역 침투의 새로운 분자 바이오마커 역할을 합니다

Article

Published on 2022-06-182022-09-11
Journal: Disease Markers [Category] MERS, 바이오마커, 진단,

Chemical profiling and unraveling of anti-COVID-19 biomarkers of red sage (Lantana camara L.) cultivars using UPLC-MS/MS coupled to chemometric analysis, in vitro study and molecular docking

화학 측정 분석, 시험관 내 연구 및 분자 도킹과 결합된 UPLC-MS/MS를 사용하여 레드 세이지(Lantana camara L.) 품종의 항-COVID-19 바이오마커의 화학적 프로파일링 및 해명

Article

Published on 2022-06-122022-09-11
Journal: Journal of ethnopharmacology [Category] COVID19(2023년), SARS, 바이오마커, 유전자 메커니즘, 치료기술, 치료제,

[키워드] (RdRp acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Analysis anti-COVID-19 activity. antiviral activity approach Asia Biomarker Biomarkers Brazil Candidates Chain Reaction Chemical chemometrics Compound Concentration coronavirus COVID-19 cytotoxicity Data analysis detect determine docked docking docking score E-gene Effect Efficacy except for exhibited exhibiting expression expression levels flavonoids flower followed by highest in vitro study In-vitro India infections inhibitor inhibitory activity interaction pattern Kenya Lantana Lantana camara L. cultivars leprosy Luteolin material mechanism metabolites metabolomics molecular docking multivariate Multivariate analysis Nigeria PCA PCA plot PCA plots plaque polymerase chain polymerase chain reaction principle profile progressed RdRP RdRp gene real-time RT-PCR Red Remdesivir required respiratory respiratory diseases respiratory virus respiratory viruses reverse transcription polymerase chain reaction rheumatism RNA-dependent RNA polymerase RT-PCR SARS-CoV-2 selectivity indices severe acute respiratory syndrome Coronavirus Spread spreading Structure sunset TaqMan target tested Transcription UPLC UPLC-MS/MS Verbenaceae Viral
[DOI] 10.1016/j.jep.2022.115038 PMC 바로가기 [Article Type] Article

Effect of thermal and chemical treatments used for SARS-COV-2 inactivation in the measurement of saliva analytes

Research

Published on 2022-06-082022-10-05
Journal: Scientific Reports [Category] COVID19(2023년), SARS, 바이오마커, 진단,

The expression patterns of MALAT-1, NEAT-1, THRIL, and miR-155-5p in the acute to the post-acute phase of COVID-19 disease

COVID-19 질병의 급성기에서 후기 급성기 MALAT1, NEAT1, THRILL 및 miR-155-5p의 발현 패턴

Article

Published on 2022-05-012022-09-11
Journal: The Brazilian journal of infectious diseases : an [Category] COVID19(2023년), SARS, 바이오마커, 진단,

[키워드] acute COVID-19 acute phase addition Analysis Biomarker COVID-19 COVID-19 diagnosis COVID-19 disease COVID-19 infection diagnose diagnosis of COVID-19 disease evaluated expression level expression levels expression pattern expression patterns hallmark hallmarks healthy control healthy individual Infection Inflammation Inflammatory factor inflammatory factors Long Long non-coding RNAs MicroRNAs miR-150 miR-155 MONITOR mononuclear cell ncRNA ncRNAs non-coding RNA Non-coding RNAs Pathogenesis pathogenesis of COVID-19 Patient PBMC peripheral Peripheral blood real-time PCR assay RNA ROC Curve selected severity of COVID-19 significantly increased significantly lower the SARS-CoV-2 THRIL Total total RNA
[DOI] 10.1016/j.bjid.2022.102354 PMC 바로가기 [Article Type] Article

Circulating miR-320b and miR-483-5p levels are associated with COVID-19 in-hospital mortality

순환하는 miR-320b 및 miR-483-5p 수준은 COVID-19 병원 내 사망률과 관련이 있습니다

Comparative Study

Published on 2022-03-012022-09-11
Journal: Mechanisms of ageing and development [Category] MERS, 바이오마커, 진단,

[키워드] adjusted Analysis analyzed Biomarker circulating circulating miRNA circulating miRNAs Cohort confounders COVID-19 COVID-19 patient Cox regression models Deceased deregulated downregulated expression levels highest Hospital mortality IMPROVE In-hospital in-hospital mortality increased risk independent invasive Kaplan-Meier management microRNA MiR-320b MiR-483-5p miRNA miRNAs molecular mortality risk Older older patients Patient Patient management Physicians qRT-PCR risk of COVID-19 RNA-Seq selected Serum level serum levels serum sample serum samples significantly Stratification survived Survivors upregulated validation cohort with COVID-19
[DOI] 10.1016/j.mad.2022.111636 PMC 바로가기 [Article Type] Comparative Study

Comparative study of SARS-CoV-2 infection in different cell types: Biophysical-computational approach to the role of potential receptors

다양한 세포 유형에서 SARS-CoV-2 감염에 대한 비교 연구: 잠재적 수용체의 역할에 대한 생물물리학적 전산적 접근

Article

Published on 2022-03-012022-09-12
Journal: Computers in biology and medicine [Category] MERS, SARS, 진단,

[키워드] A549 ACE2 addition AGTR2 angiotensin-converting enzyme 2 approach CD147 Cell cell line cell lines Cell susceptibility cellular Comparative conditions dependent on docking early infection expected experiment expression expression level expression levels greater Heat shock HEK293 HepG2 Host host protein HSPA5 Infection Interaction kinetic less Lungs macromolecular Macromolecular crowding membrane NRP1 NTERA-2 parameter predict predicted promote protease Protein Quantitative receptor receptors Research respiratory tract SARS CoV-2 SARS-COV-2 infection serine 2 stimulate susceptibility TMPRSS2 transcriptomic data transmembrane viral dynamics viral growth viral spike Viral spike. virus
[DOI] 10.1016/j.compbiomed.2022.105245 PMC 바로가기 [Article Type] Article

Aging whole blood transcriptome reveals candidate genes for SARS-CoV-2-related vascular and immune alterations

노화된 전혈 전사체는 SARS-CoV-2 관련 혈관 및 면역 변화에 대한 후보 유전자를 나타냅니다

Article

Published on 2022-02-012022-09-11
Journal: Journal of Molecular Medicine (Berlin, Germany) [Category] COVID19(2023년), SARS, 유전자 메커니즘,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 addition adhesion affected age aging alteration anti-apoptotic BAG3 Blood Blood clots blood component blood components candidate candidate gene cascade cathepsin Cathepsins CCL4L2 CD14 CD4 CD8 Cell changes in clinical manifestation coronavirus COVID-19 CTSE CTSW database DEGs differentially expressed gene Differentially expressed genes DUSP4 expressed expression expression levels expression profile FASL FASLG female genders gene expression profile high viral load highest HLA-DRA Hyperinflammatory identify IFN IFN signaling immune immune response increase increase in increased expression individual Inflammation interact Interaction interferon investigated involved LAG3 Monocytes naïve T cells natural killer cell Natural killer cells Older older patient older patients overexpress overexpression PDCD1 Peripheral blood Platelet prediction Protein reveal RGS2 risk SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2-infected patient SARS-CoV-2-infected patients sequencing data severe acute respiratory syndrome Coronavirus severe COVID-19 Signaling Single-cell RNA-sequencing T cell T cell exhaustion T cells T lymphocytes target targets therapeutic TIGIT TOX Transcriptome translated type I interferon Vascular VCAM1 Viral load Viral protein Viral proteins Whole blood whole blood transcriptome
[DOI] 10.1007/s00109-021-02161-4 PMC 바로가기 [Article Type] Article

Assessment of ACE1 variants and ACE1/ACE2 expression in COVID-19 patients

COVID-19 환자에서 ACE1 변이체 및 ACE1/ACE2 발현 평가

Article

Published on 2022-02-012022-09-11
Journal: Vascular pharmacology [Category] COVID19(2023년), SARS, 변종, 유전자 메커니즘,

[키워드] ACE ACE1 ACE1 gene ACE1/ACE2 ACE2 ACE2 expression Affect allele angiotensinogen assessment association carrier carriers circulation Complication Control controls COVID-19 COVID-19 patient distribution ether examined expression expression level expression levels Expression. Frequency Genotype genotyped genotypes groups healthy controls I/D polymorphism ICU patient ICU Patients mRNA level non-ICU non-ICU patient non-ICU patients not different not significantly different p value Patient patients polymorphism Renin risk of COVID-19 significantly higher study groups total population transcripts two group two groups variant while
[DOI] 10.1016/j.vph.2021.106934 PMC 바로가기 [Article Type] Article

Poly-l-Lysine-Modified Graphene Field-Effect Transistor Biosensors for Ultrasensitive Breast Cancer miRNAs and SARS-CoV-2 RNA Detection

초민감성 유방암 miRNA 및 SARS-CoV-2 RNA 검출을 위한 폴리-리신-변형 그래핀 전계 효과 트랜지스터 바이오센서

Article

Published on 2022-01-252022-09-11
Journal: Analytical Chemistry [Category] SARS, 유전자 메커니즘, 치료기술,