Atomic-Resolution Structure of SARS-CoV-2 Nucleocapsid Protein N-Terminal DomainSARS-CoV-2 뉴클레오캡시드 단백질 N-말단 도메인의 원자 분해능 구조Article Published on 2022-06-152022-09-11 Journal: Journal of the American Chemical Society [Category] COVID19(2023년), SARS, 치료기술, 치료법, 치료제, [키워드] addition approach atomic bind binding experiment flexible genome organization genomic RNA Guidance in viral Infection information inhibitor means N- and C-termini N-terminal domain NMR NTD nucleocapsid offer pathogenicity Protein provide Region Replication RNA SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 virus structural protein structural proteins Structure the SARS-CoV-2 the SARS-CoV-2 virus therapeutic intervention therapeutic interventions Vaccine development X-ray diffraction [DOI] 10.1021/jacs.2c03320 PMC 바로가기 [Article Type] Article
Chromosomes Conformation Capture Coupled with Next-Generation Sequencing (Hi-C) in Plasmodium falciparumarticle Published on 2021-12-312024-09-01 Journal: Methods in molecular biology (Clifton, N.J.) [Category] 말라리아, [키워드] genome organization Hi-C Plasmodium falciparum virulence [Article Type] article
Interspecies Jumping of Bat Coronaviruses박쥐 코로나 바이러스의 산간 점프Review Published on 2021-10-292022-09-10 Journal: Viruses [Category] MERS, SARS, 치료기술, [키워드] bat bats caused chance China Chinese Horseshoe bats coronavirus CoV COVID-19 CoVs disease disease outbreaks Epidemic epidemics/pandemics event events experiments fatality Genome genome organization genomic studies genomic study horseshoe horseshoe bats Human interspecies jumping Jumping measure MERS MERS-CoV MONITOR Mortality occurred outbreak pandemic Pandemics Patient Phylogenetic Pipistrellus Pneumonia PROTECT public health recombineering reduce reported reservoir SADS SARS SARS epidemic SARS-CoV SARS-CoV-2 SARS-related CoV Spread Threats Transmission Tylonycteris virus Wuhan Wuhan, China [DOI] 10.3390/v13112188 PMC 바로가기 [Article Type] Review
Features of Pathobiology and Clinical Translation of Approved Treatments for Coronavirus Disease 2019Review Article Published on 2021-10-252023-07-02 Journal: Intervirology [Category] SARS, [키워드] COVID-19 genome organization pathogenic mechanisms SARS-CoV-2 [DOI] 10.1159/000520234 PMC 바로가기 [Article Type] Review Article
Evolution, Interspecies Transmission, and Zoonotic Significance of Animal CoronavirusesVeterinary Science Published on 2021-10-182022-11-01 Journal: Frontiers in Veterinary Science [Category] COVID-19, [키워드] accessory proteins Affect animal Animal coronaviruses classification coronavirus Evolution explain Factor gastrointestinal tract genome organization groups help highlight host cell receptor Human infecting interspecies transmission mammal motif mutate outcomes Pandemics protein binding motif rodent sequence Significance single-stranded RNA virus These viruses tissue tissues Transmission variants of concern variety wild animals zoonotic zoonotic animal origin [DOI] 10.3389/fvets.2021.719834 PMC 바로가기 [Article Type] Veterinary Science
In vivo structure and dynamics of the SARS-CoV-2 RNA genomeArticle Published on 2021-09-282022-10-04 Journal: Nature Communications [Category] SARS, 유전자 메커니즘, 치료제, [키워드] 3′-UTR 5′-UTR addition Analysis Antiviral strategies canonical Cell conformation develop discontinuous transcription domain Evidence facilitate functional Genome genome organization help in vivo Intensive Interaction Local Regulating Regulation Replication reveal RNA RNA genome RNA secondary structure SARS-CoV-2 SARS-CoV-2 genome SARS-CoV-2 RNA sequences Structure the SARS-CoV-2 Transcription translation translational viral life cycle viral replication virions weakened [DOI] 10.1038/s41467-021-25999-1 PMC 바로가기 [Article Type] Article
Animal Coronavirus Diseases: Parallels with COVID-19 in HumansReview Published on 2021-07-302022-10-28 Journal: Viruses [Category] COVID-19, SARS, [키워드] acute respiratory syndrome animal animal coronavirus caused Clinical signs complement coronavirus Coronavirus disease 2019 Coronaviruses COVID-19 COVID-19 pandemic Critical described Diagnosis disease DIVA effective vaccine genome organization handling Human humans Immunopathogenesis Intensive Novel coronavirus Outbreaks pathophysiological mechanism Perspective public health Recombination recorded Research SARS-CoV-2 subject Transmission Treatment viral shedding viruses with COVID-19 [DOI] 10.3390/v13081507 PMC 바로가기 [Article Type] Review
Genome-Wide Analysis of Codon Usage Patterns of SARS-CoV-2 Virus Reveals Global Heterogeneity of COVID-19SARS-COV-2 바이러스의 코돈 사용 패턴의 게놈 전체 분석은 COVID-19의 글로벌 이질성을 보여줍니다.Article Published on 2021-06-182022-09-10 Journal: Biomolecules [Category] MERS, SARS, 변종, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 can not causative agents characterized codon codon usage Codon usage bias comprehensive analysis coronavirus coronavirus disease coronavirus disease COVID-19 COVID-19 error genome organization geographic location global genome global genomes globe heterogeneity heterogeneity of COVID-19 Host host adaptation implicated lack margin margin of error Mutation Mutational bias natural selection outbreak pattern performed reduce Research respiratory Sample size SARS-CoV-2 SARS-CoV-2 genome SARS-CoV-2 viral selection pressure severe acute respiratory syndrome Coronavirus significantly Standard deviation strain Strains Support Taking the SARS-CoV-2 the SARS-CoV-2 genome Usage Viral viral genome viral lineage viral strains virus virus genome whole genome [DOI] 10.3390/biom11060912 PMC 바로가기 [Article Type] Article
Epigenetic regulation of ACE2, the receptor of the SARS-CoV-2 virus1Review Published on 2021-04-012023-07-06 Journal: Genome [Category] SARS, [키워드] Angiotensin-converting enzyme 2 (ACE2) enzyme de conversion de l’angiotensine 2 (ACE2) Epigenetic épigénétique. genome organization histone and DNA modifications modifications de l’ADN et des histones organisation du génome SARS-CoV-2 [DOI] 10.1139/gen-2020-0124 [Article Type] Review
SARS-CoV-2: An Update on Genomics, Risk Assessment, Potential Therapeutics and Vaccine DevelopmentSARS-CoV-2: 유전체학, 위험 평가, 잠재적 치료제 및 백신 개발에 대한 업데이트Review Published on 2021-02-082022-09-10 Journal: International Journal of Environmental Research an [Category] MERS, 유전자 메커니즘, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus assessment Awareness Care causative pathogen children coronavirus coronavirus disease country COVID-19 COVID-19 vaccines development effort Genome genome organization genomic characterization Genomics Health care health care workers help individual information MERS MERS-CoV Mutation pandemic pathophysiology Potential public health reduce reported Research researcher respiratory risk factor SARS-CoV SARS-CoV-2 SARS-CoV-2 virus severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 similarity specific mutation specific mutations Spread spread to susceptible Symptoms therapeutic option Therapeutic strategies therapeutic strategy Therapeutics Transmission Transmission dynamics Vaccine development virus [DOI] 10.3390/ijerph18041626 PMC 바로가기 [Article Type] Review