Prevalence of glucose-6-phosphate dehydrogenase (G6PD) deficiency in Gia Lai Province, Vietnamarticle Published on 2024-06-302024-09-01 Journal: Parasitology International [Category] 말라리아, [키워드] Central Highland glucose-6-phosphate dehydrogenase deficiency Viangchan variant Vietnam [Article Type] article
Is glucose-6-phosphatase dehydrogenase deficiency associated with severe outcomes in hospitalized COVID-19 patients?Article Published on 2021-09-282022-10-04 Journal: Scientific Reports [Category] SARS, 치료법, [키워드] 95% confidence interval age aggravate antioxidant association COVID-19 patients deficiency Epidemiology glucose-6-phosphate dehydrogenase deficiency Hospitalized hospitalized COVID-19 hospitalized COVID-19 patient Intervention intubation likelihood non-invasive ventilation not significantly different Occurrence outcome Outcomes research Patient presence of comorbidity Research Respiratory signs and symptoms Risk factors severe COVID-19 severity of COVID-19 suppress viral infection [DOI] 10.1038/s41598-021-98712-3 PMC 바로가기 [Article Type] Article
Glucose-6-phosphate dehydrogenase deficiency and hydroxychloroquine in the COVID-19 era: a mini reviewCOVID-19 시대의 포도당-6-인산 탈수소효소 결핍과 하이드록시클로로퀸: 미니 리뷰Review Published on 2021-03-012022-09-11 Journal: Molecular biology reports [Category] MERS, 신약개발, 진단, 치료제, [키워드] activities addition antiviral agent Antiviral agents association caused Cellular immune response Chloroquine coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 infection COVID-19 pandemic COVID-19 patient COVID-19 patients cytokine deficiency effective effective drug effective drugs effort Final G6PD G6PD deficiency glucose-6-phosphate dehydrogenase deficiency HCQ health emergency hemoglobin Hemolysis hemolytic hemolytic anemia Hemolytic crisis Hydroxychloroquine immune responses in vitro inflammasome activation Innocent Intensive involved limelight modulating occur oxygen Patient patients performed Prevent pro-inflammatory cytokine question raised reactive oxygen species reactive oxygen specy Safe searched shown today treat [DOI] 10.1007/s11033-021-06234-y PMC 바로가기 [Article Type] Review
Therapeutic Intervention of COVID-19 by Natural Products: A Population-Specific Survey Directed Approach천연물에 의한 COVID-19의 치료적 개입: 특정 인구 조사 지향 접근법Review Published on 2021-02-232022-09-10 Journal: Molecules [Category] MERS, 진단, 치료제, [키워드] activity addition Antiviral approach can be used Cell Community Comorbidity Compound COVID-19 Critical cytokine Cytokine storm deficiency Disparities docking study Effect enzymopathy Factor focus G6PD Genetic genetic factors Genome Glucose Glucose-6-phosphate glucose-6-phosphate dehydrogenase glucose-6-phosphate dehydrogenase deficiency Health host response immune responses immunomodulatory property IMPROVE in vitro in-silico in-silico docking include independent independent of individual innate immune responses Intervention lead leads life style variables management molecular natural natural product outcomes Prevalence protein targets rationale review risk factor Risk factors SARS-CoV-2 SARS-COV-2 infection Secondary Metabolite secondary metabolites selected survey targets the cytokine storm therapeutic intervention therapeutic interventions Treatment variable Viral viral infection virulence [DOI] 10.3390/molecules26041191 PMC 바로가기 [Article Type] Review
Protective effect of Mediterranean-type glucose-6-phosphate dehydrogenase deficiency against Plasmodium vivax malaria지중해형 포도당-6-인산 탈수소효소 결핍이 말라리아 원충 비바크스에 대한 보호 효과Article Published on 2021-02-052024-08-08 Journal: eLife [Category] 말라리아, [키워드] enzymopathy G6PD glucose-6-phosphate dehydrogenase deficiency malaria Other Plasmodium vivax primaquine [DOI] 10.7554/eLife.62448 PMC 바로가기
Home Treatment of Older People with Symptomatic SARS-CoV-2 Infection (COVID-19): A structured Summary of a Study Protocol for a Multi-Arm Multi-Stage (MAMS) Randomized Trial to Evaluate the Efficacy and Tolerability of Several Experimental Treatments to Reduce the Risk of Hospitalisation or Death in outpatients aged 65 years or older (COVERAGE trial)증상이 있는 SARS-CoV-2 감염(COVID-19)이 있는 고령자의 가정 치료: 여러 가지 실험적 치료의 효능과 내약성을 평가하기 위한 MAMS(Multi-Arm Multi-Stage) 무작위 시험에 대한 연구 프로토콜의 구조화된 요약 65세 이상 외래 환자의 입원 또는 사망 위험 감소(COVERAGE 시험)Letter Published on 2020-10-132022-08-13 Journal: Trials [Category] MERS, SARS, 임상, [키워드] 6-mercaptopurine Abnormalities ACEi added age amodiaquine Analysis antrafenine approved ARB ARBs Arm azathioprine Blinding Bordeaux Caregivers Chloroquine chronic hepatitis Chronic kidney disease citalopram clinical Colitis Combination comparator complex conducted Control control arm COVID-19 COVID-19 pandemic criteria CYP3A4 cytochrome P450 Dasatinib death Dementia dialysis dissemination Domperidone drug Duchy Efficacy element enrolled enrolment Enterocolitis escitalopram EudraCT Evidence exclusion criteria experimental arm experimental drug Experimental drugs Favipiravir feasibility Final final analysis first symptom first symptoms floctafenine France French futility galactose GFR glafenine Glucose Glucose-6-phosphate glucose-6-phosphate dehydrogenase glucose-6-phosphate dehydrogenase deficiency Grand duchy halofantrine Health Insurance heart rate hepatic Hepatic porphyria home hospital hospitalisation Hydroxychloroquine hydroxyzine hypersensitivity Hyperuricemia Ileus Imatinib immunological incidence Inclusion increase in inducer inhibitor Interim analyses interim analysis intervals investigator investigators Isoenzyme Kidney disease Lactase Lactose liver failure Long Long QT syndrome Luxembourg malabsorption mefloquine mercaptopurine metabolism multi multi-arm nasopharyngeal Nasopharyngeal swab New Nilotinib not blinded number nursing home nursing homes objective Older Open-label open-label trial other treatment other treatments outcome Outpatient P450 Paris participant Patient performed phase Piperaquine Positive test Prevent primary care Primary outcome proportion protocol pyrazinamide QTc interval randomisation randomised Randomized Randomly receive recruited Region Registered regulatory authority repaglinide replaced REPLACED BY reported Repurposed drug residence Safety Monitoring Board Sample size SARS-CoV-2 SARS-COV-2 infection scale Stage Standard statistician statisticians status stratified Study protocol submitted symptomatic SARS-CoV-2 infection Tablet telmisartan tested theophylline Toxicity Trace element trace elements treated Treatment treatment arm Trial Trial registration Version virus Virus Disease Vitamin vitamins Warfarin [DOI] 10.1186/s13063-020-04619-1 PMC 바로가기 [Article Type] Letter
Investigation of glucose-6-phosphate dehydrogenase (G6PD) deficiency prevalence in a Plasmodium vivax -endemic area in the Republic of Korea (ROK)한국(ROK)에서 Plasmodium vivax가 유행하는 지역의 포도당-6-인산 탈수소효소(G6PD) 결핍 유병률 조사Research Published on 2020-09-012024-08-11 Journal: Malaria Journal [Category] 말라리아, [키워드] glucose-6-phosphate dehydrogenase deficiency Prevalence primaquine Single nucleotide polymorphism [DOI] 10.1186/s12936-020-03393-4 PMC 바로가기 [Article Type] Research
Proactive Prophylaxis With Azithromycin and HydroxyChloroquine in Hospitalised Patients With COVID-19 (ProPAC-COVID): A structured summary of a study protocol for a randomised controlled trialLetter Published on 2020-06-102022-10-29 Journal: Trials [Category] Coronavirus, SARS, [키워드] 1:1 Administered age antibiotic antiviral efficacy Asthma Azithromycin Beta blocker blinded block calcium cardiovascular change changed chronic clinical combination therapy Control control group coordinator COPD COVID-19 COVID-19 test Day days alive death derivative Diagnosis Direct Current discharged disorder dissemination double-blind study ECG element ergot alkaloid expected Final FiO2 generate Glucose glucose-6-phosphate dehydrogenase deficiency guide hearing loss hematological hospital hospitalisation Hospitalization hospitals Hydroxychloroquine hypersensitivity impede Inclusion Informed consent intensive care Interstitial lung disease Intervention intervention group invasive ventilation investigated investigator Liver disease lung maculopathy medication mental illness modulation myasthenia gravis negative pregnancy test network Neurogenic neurological number objective offered outcome parallel group participant Patient patients with COVID-19 Placebo pregnant Primary outcome problem protocol psoriasis pulmonary QTc QTc interval randomisation randomised randomised controlled trial receive recruited recruitment reduce Registered reported respiratory infections retinopathy risk Sample size sequence significantly Sponsor Standard standard care standard treatment status Stratification Study protocol the patient therapy treated Treatment Trial Visual field website women [DOI] 10.1186/s13063-020-04409-9 PMC 바로가기 [Article Type] Letter
[Glucose-6-phosphate-dehydrogenase deficiency management in western countries. A literature review]article Published on 2020-02-282024-09-01 Journal: SEMERGEN - Medicina de Familia [Category] 말라리아, [키워드] Atención primaria Deficiencia de glucosafosfato deshidrogenasa glucose-6-phosphate dehydrogenase deficiency Immigration Inmigración Primary Health Care [Article Type] article
Hemolytic Dynamics of Weekly Primaquine Antirelapse Therapy Among Cambodians With Acute Plasmodium vivax Malaria With or Without Glucose-6-Phosphate Dehydrogenase Deficiency주간 프리마퀸 항재발 치료의 용혈 역학: 포도당-6-인산 탈수소효소 결핍 여부에 따른 캄보디아의 급성 플라스모디움 비박스 말라리아 환자들 사이에서Article Published on 2019-12-012024-08-11 Journal: Nanoscale [Category] 말라리아, [키워드] Cambodia glucose-6-phosphate dehydrogenase deficiency hemoglobin E malaria primaquine [DOI] 10.1093/infdis/jiz313 PMC 바로가기