Integrating transcriptomics, glycomics and glycoproteomics to characterize hepatitis B virus-associated hepatocellular carcinomaResearch Published on 2024-04-012024-09-05 Journal: Cell Communication and Signaling : CCS [Category] update2024, [키워드] fucosylation glycomics glycoproteomics HBV-associated HCC transcriptomics [DOI] 10.1186/s12964-024-01569-y PMC 바로가기 [Article Type] Research
Decoding the glycoproteome: a new frontier for biomarker discovery in cancerReview Published on 2024-03-222024-09-05 Journal: Journal of Hematology & Oncology [Category] update2024, [키워드] Biomarker Cancer glycoproteomics Screening [DOI] 10.1186/s13045-024-01532-x PMC 바로가기 [Article Type] Review
The role of N -glycosylation in spike antigenicity for the SARS-CoV-2 gamma variantOriginal Article Published on 2024-02-042024-09-05 Journal: Glycobiology [Category] update2024, [키워드] antibodies coronavirus glycoprotein glycoproteomics mass spectrometry [DOI] 10.1093/glycob/cwad097 PMC 바로가기 [Article Type] Original Article
The glycobiology of plasmodium falciparum: New approaches and recent advancesArticle Published on 2023-09-302024-09-10 Journal: Biotechnol Adv [Category] 말라리아, [키워드] glycans glycobiology Glycoconjugates glycoproteomics lectins malaria Plasmodium falciparum PMC 바로가기
The Role of Clinical Glyco(proteo)mics in Precision Medicinearticle Published on 2023-05-092024-09-05 Journal: Molecular & Cellular Proteomics [Category] update2024, [키워드] Biomarker clinical Diagnosis glycomics glycoproteomics lab-developed test multimarker quantification therapy [DOI] 10.1016/j.mcpro.2023.100565 PMC 바로가기 [Article Type] article
Improving Statistical Certainty of Glycosylation Similarity between Influenza A Virus Variants Using Data-Independent Acquisition Mass SpectrometryArticle Published on 2022-11-012023-06-23 Journal: Molecular & Cellular Proteomics : MCP [Category] 신종인플루엔자, [키워드] DIA glycoproteomics glycosylation similarity hemagglutinin Influenza mass spectrometry [DOI] 10.1016/j.mcpro.2022.100412 PMC 바로가기
Sialic Acid and Fucose Residues on the SARS-CoV-2 Receptor-Binding Domain Modulate IgG Antibody ReactivityArticle Published on 2022-09-092022-11-15 Journal: ACS Infectious Diseases [Category] SARS, 진단, [키워드] acid antibody antibody reactivity carbohydrate cells Chinese hamster conserved defined domain embryonic kidney cell ENhance evaluated exhibited fucose generate glycoepitope glycoproteomics IgG less mammalian cells mass spectrometry modulated monosaccharides N-linked glycans Neutralizing antibodies produced Protein RBD reactivity Receptor binding domain reduced removal SARS-CoV-2 SARS-CoV-2 positive patients serum sample sialic acid Spike protein Structure the RBD the RBD protein the SARS-CoV-2 vaccine candidates Viral proteins [DOI] 10.1021/acsinfecdis.2c00155 PMC 바로가기
Strategies for Proteome-Wide Quantification of Glycosylation Macro- and Micro-HeterogeneityReview Published on 2022-01-302022-10-29 Journal: International Journal of Molecular Sciences [Category] COVID-19, [키워드] biological sample Biomarker changes changes in Disease progression glycoproteomics glycosylation human cells human disease improvement label free limitations macro mass spectrometry methodology physiological promote proteome quantification Quantitative Regulation sensitivity stable-isotope labeling Strategy therapeutic targets [DOI] 10.3390/ijms23031609 PMC 바로가기 [Article Type] Review
Data-independent acquisition mass spectrometry for site-specific glycoproteomics characterization of SARS-CoV-2 spike proteinResearch Paper Published on 2021-10-122023-06-15 Journal: Analytical and bioanalytical chemistry [Category] MERS, SARS, [키워드] DIA glycoproteomics glycosylation mass spectrometry SARS-CoV-2 Spike protein [DOI] 10.1007/s00216-021-03643-7 PMC 바로가기 [Article Type] Research Paper
A Linkage-specific Sialic Acid Labeling Strategy Reveals Different Site-specific Glycosylation Patterns in SARS-CoV-2 Spike Protein Produced in CHO and HEK Cell SubstratesChemistry Published on 2021-09-242022-10-31 Journal: Frontiers in Chemistry [Category] COVID-19, [키워드] ACE2 acid acute respiratory syndrome amidation ammonium hydroxide C-terminal trimerization motif cell substrate cells Chinese hamster CHO cell complex coronavirus determine diagnostics dimethylamine embryonic kidney EThcD evaluate exhibit Express glycan glycan shield glycoproteomics glycosylated glycosylation HEK cell high-mannose Host host immune system immune system Interaction modify N-glycosylation N-linked glycosylation pattern predicted presenting produced profile Protein reaction receptor recombinant S protein Research reveal S protein SARS-CoV-2 sialic acid site occupancy spike Spike protein Spike proteins Strategy substrate Support suspensions the S protein the SARS-CoV-2 These data transmembrane domain Vaccines viral envelope virus [DOI] 10.3389/fchem.2021.735558 PMC 바로가기 [Article Type] Chemistry