Tenovin-1, a Selective SIRT1/2 Inhibitor, Attenuates High-fat Diet-induced Hepatic Fibrosis via Inhibition of HSC Activation in ZDF RatsResearch Paper Published on 2024-06-112024-09-05 Journal: International Journal of Biological Sciences [Category] update2024, [키워드] hepatic fibrosis Hepatic stellate cells High-fat diet Inflammation oxidative stress Tenovin-1 [DOI] 10.7150/ijbs.97304 PMC 바로가기 [Article Type] Research Paper
Expression of miR-223-3p in patients with hepatitis B virus liver fibrosis and its effect on hepatic stellate cells: An observational studyResearch Article: Observational Study Published on 2023-07-282024-09-05 Journal: Medicine [Category] update2024, [키워드] hepatic fibrosis Hepatic stellate cells Hepatitis B virus miR-223-3p signaling pathway [DOI] 10.1097/MD.0000000000034454 PMC 바로가기 [Article Type] Research Article: Observational Study
Antifibrotic therapy in nonalcoholic steatohepatitis: time for a human-centric approachPerspective Published on 2023-06-022024-09-05 Journal: Nature reviews. Gastroenterology & hepatology [Category] update2024, [키워드] Hepatic stellate cells Liver fibrosis Non-alcoholic fatty liver disease non-alcoholic steatohepatitis [DOI] 10.1038/s41575-023-00796-x PMC 바로가기 [Article Type] Perspective
Cell atlas of CCl 4 -induced progressive liver fibrosis reveals stage-specific responsesArticle Published on 2023-05-182024-09-05 Journal: Zoological research [Category] update2024, [키워드] Angiogenesis cell-cell interactions Gene regulatory networks Hepatic stellate cells hepatocytes Liver fibrosis Single-cell and single-nucleus RNA-sequencing Toxicity [DOI] 10.24272/j.issn.2095-8137.2023.031 PMC 바로가기 [Article Type] Article
Insights into the impact of hepatitis B virus on hepatic stellate cell activationReview Published on 2023-04-112023-06-13 Journal: Cell Communication and Signaling : CCS [Category] B형 간염, [키워드] Hepatic stellate cells Hepatitis B virus Inflammation Liver fibrosis [DOI] 10.1186/s12964-023-01091-7 PMC 바로가기 [Article Type] Review
SARS-CoV-2-mediated liver injury: pathophysiology and mechanisms of diseaseReview Published on 2023-02-012023-07-11 Journal: Inflammation research : official journal of the Eu [Category] COVID19(2023년), [키워드] ACE 2 receptors acute liver failure Ang2 Chronic liver failure COVID-19 Cytokine storm Hepatic stellate cells Inflammation [DOI] 10.1007/s00011-022-01683-y PMC 바로가기 [Article Type] Review
The histologic and molecular correlates of liver disease in fatal COVID-19 including with alcohol use disorder알코올 사용 장애를 포함한 치명적인 COVID-19에서 간 질환의 조직학적 및 분자적 상관관계Article Published on 2022-04-012022-09-11 Journal: Annals of diagnostic pathology [Category] 진단, 치료법, [키워드] ACE2 ACE2 expression activated activated macrophages alcohol Alcohol Abuse Alcohol liver disease Cell Control COVID-19 disease disorder endocytosed envelope proteins evidenced experiment expression fatal COVID-19 greater hepatic hepatic disease hepatic stellate cell Hepatic stellate cells Hepatitis higher risk histologic histologic findings IL6 induce Inflammation injection liver Liver disease livers lobular inflammation Macrophage macrophages mice molecular nucleocapsid protein Patient positive Protein RNA robust SARS-CoV-2 spike protein SARS-CoV2 SARS-CoV2 infection severe COVID-19 severe liver disease significantly spike Spike protein subunit the spike protein TNFα Viral viral spike protein western blots [DOI] 10.1016/j.anndiagpath.2021.151881 PMC 바로가기 [Article Type] Article
Co-culture Model for Hepatitis B Virus Infection Using iPSC-Derived Liver Progenitor Cells and Liver Sinusoidal Endothelial CellsArticle Published on 2022-01-012023-06-12 Journal: Methods in molecular biology (Clifton, N.J.) [Category] B형 간염, [키워드] Co-culture system Hepatic stellate cells Hepatitis B virus liver Liver sinusoidal endothelial cells. [DOI] 10.1007/978-1-0716-2557-6_7
Intrahepatic T helper 17 cells recruited by hepatitis B virus X antigen-activated hepatic stellate cells exacerbate the progression of chronic hepatitis B virus infectionArticle Published on 2020-11-012023-06-12 Journal: Journal of viral hepatitis [Category] B형 간염, [키워드] hepatic cirrhosis Hepatic stellate cells hepatitis B virus X antigen (HBxAg) Hepatocellular carcinoma Th17 cell [DOI] 10.1111/jvh.13352
TLR3 Activation of Hepatic Stellate Cell Line Suppresses HBV Replication in HepG2 CellsOriginal Research Published on 2018-12-172023-06-03 Journal: Frontiers in Immunology [Category] B형 간염, Fulltext, [키워드] Hepatic stellate cells Hepatitis B virus interferon-β interferon-λ interferon-stimulated genes Toll-like receptor 3 [DOI] 10.3389/fimmu.2018.02921 PMC 바로가기 [Article Type] Original Research