Low Bone Mineral Density and Associated Risk Factors in Elite Cyclists at Different Stages of a Professional Cycling CareerApplied Sciences Published on 2023-05-262024-09-05 Journal: Medicine & Science in Sports & Exercise [Category] update2024, [키워드] bone mineral density Cycling ENERGY AVAILABILITY Fracture IGF-1 T3 [DOI] 10.1249/MSS.0000000000003113 PMC 바로가기 [Article Type] Applied Sciences
Evaluation serum levels of Insulin Growth Factor-1 (IGF-1) and its association with clinical parameters in severe COVID-19Original Article Published on 2022-01-312023-06-15 Journal: Inflammopharmacology [Category] COVID19(2023년), MERS, SARS, [키워드] age Clinical parameters IGF-1 severe COVID-19 [DOI] 10.1007/s10787-021-00908-6 PMC 바로가기 [Article Type] Original Article
The effect of IGF-1 plasma concentration on COVID-19 severityArticle Published on 2022-01-262023-06-15 Journal: Microbial pathogenesis [Category] MERS, SARS, [키워드] Coronavirus infection COVID-19 IGF-1 immune system response SARS-CoV-2 [DOI] 10.1016/j.micpath.2022.105416 PMC 바로가기 [Article Type] Article
Role of Extracellular Vimentin in Cancer-Cell Functionality and Its Influence on Cell Monolayer Permeability Changes Induced by SARS-CoV-2 Receptor Binding DomainArticle Published on 2021-07-122022-10-29 Journal: International Journal of Molecular Sciences [Category] COVID-19, [키워드] activated macrophages Activation activation pathway addition Alter angiotensin-converting enzyme 2 Astrocyte Bacterial bind binding binding domain Cancer Cancer cells cancer progression Cell Cell migration cells cellular change cytoskeletal domain Effect ENhance Extracellular extracellular space extracellular vimentin functional functions growth IGF-1 IGF-1 receptor induced Inflammation influence investigated involved MCF-7 Migration modulate modulation monolayer monolayers neutrophil infiltration overexpressed permeability physiological conditions proliferation promote Protein receptor Receptor binding domain reduced reduction role SARS-CoV-2 SARS-CoV-2 infections SARS-CoV-2 receptor SARS-COV-2 receptor binding domain SARS-CoV-2 spike protein secreted shown Spike protein Support surface the SARS-CoV-2 Treatment vimentin viral infection while [DOI] 10.3390/ijms22147469 PMC 바로가기 [Article Type] Article
Covid-19 and Growth Hormone/Insulin-Like Growth Factor 1: Study in Critically and Non-Critically Ill PatientsEndocrinology Published on 2021-06-162022-10-31 Journal: Frontiers in Endocrinology [Category] COVID-19, MERS, SARS, [키워드] Admission APACHE II association Blood calculated control patients controls Critically ill patient Factor Glucose groups growth factor growth hormone hospital Hospitalization humans ICU IGF-1 IGF1 Ill insulin-like growth factor 1 Laboratory laboratory parameter lactate dehydrogenase non-critically ill patient non-survivor normalized objective Older outcome Pandemics Patient Pneumonia prognostic Prognostic value raw data Result SDS severe acute respiratory syndrome coronavirus 2 significant difference SOFA Standard deviation survivor White blood cell [DOI] 10.3389/fendo.2021.644055 PMC 바로가기 [Article Type] Endocrinology
Association of Circulating Sex Hormones With Inflammation and Disease Severity in Patients With COVID-19Research Published on 2021-05-252022-10-29 Journal: JAMA Network Open [Category] COVID-19, SARS, [키워드] 95% CI Admission age association C-reactive protein CD14 CD16 cellular signaling pathways circulating classical clinical trial cohort study collected Concentration concentrations conducted consecutive patient contribute COVID-19 COVID-19 illness diagnosed disease disease severity enrichment analysis estradiol exposure finding growth factor hepatocyte growth factor hormone hormone concentration Hospitalization Hospitalized Hypothesis IGF-1 Importance Inflammation Inflammatory cytokine intensive care interferon male measure median men monocyte mononuclear cell nasopharyngeal swabs objective outcome participant pathophysiologic Patient patients with COVID-19 Point predisposition prospective cohort study Protein receptor regulated Relevance remained required Result risk factor RNA sequencing serum serum sample setting severe COVID-19 severe COVID-19 illness severity Sex sex hormone Signaling signaling pathway single-center Testosterone the patient Treatment upregulated upregulation was performed were measured with COVID-19 women [DOI] 10.1001/jamanetworkopen.2021.11398 PMC 바로가기 [Article Type] Research
Physical exercise effects on the brain during COVID-19 pandemic: links between mental and cardiovascular healthCOVID-19 전염병 동안 뇌에 미치는 신체 운동 효과: 정신 건강과 심혈관 건강 간의 연관성Review Published on 2021-04-012022-09-11 Journal: Neurological Sciences [Category] 유전자 메커니즘, [키워드] ACE2 ACE2 expression Activation acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 addition Affect affected Ang 1-7 angiotensin Angiotensin-converting enzyme angiotensin-converting enzyme-2 antiinflammatory Anxiety BDNF binding Brain cardiovascular complications Cardiovascular health caused Chronic diseases Corona Corona virus coronavirus COVID-19 COVID-19 pandemic death Depression disorders Effect Elevation ENhance enzyme ERK exercise FNDC5 Health heart host cell host cells IGF-1 IMPROVE individual induce Infection Inflammation life lung Lungs maintenance Mental mental health Mobility molecular mechanism molecular mechanisms neurological neuronal other tissues outbreak oxygen oxygen supply pandemic pathological mechanism pathway physical physical activity Physical exercise physiological response PI3K Quality of life quarantine Quarantine period receptor reducing SARS-CoV-2 SARS-COV-2 infection Sedentary behavior severe acute respiratory syndrome Coronavirus survival Treatment Virus Disease [DOI] 10.1007/s10072-021-05082-9 PMC 바로가기 [Article Type] Review
Pre-diagnostic circulating concentrations of insulin-like growth factor-1 and risk of COVID-19 mortality: results from UK Biobank인슐린 유사 성장 인자-1의 사전 진단 순환 농도 및 COVID-19 사망 위험: UK Biobank의 결과Article Published on 2021-03-012022-09-11 Journal: European Journal of Epidemiology [Category] SARS, 바이오마커, [키워드] 95% CI 95% confidence interval association baseline circulating CIs Concentration concentrations coronavirus coronavirus disease Coronavirus disease 2019 Coronavirus infection correlation coefficient COVID-19 COVID-19 mortality COVID-19 patient COVID-19 patients COVID-19 prognosis death deteriorate determine deviation Endocrine growth factor highest IGF-1 immune system implicated IMPROVE Inflammatory Injury insulin insulin-like growth factor insulin-like growth factor-1 investigated log-transformed Logistic regression lower risk lowest Mortality mortality risk occurred Odds ratio pathway Prognosis quartile reduction in required resource risk risk of COVID-19 SARS-CoV-2 Sensitivity analyses serum stratified UK biobank was performed [DOI] 10.1007/s10654-020-00709-1 PMC 바로가기 [Article Type] Article
A Suggested Role of Human Growth Hormone in Control of the COVID-19 PandemicCOVID-19 전염병 통제에서 인간 성장 호르몬의 제안된 역할Endocrinology Published on 2020-11-092022-09-11 Journal: Frontiers in Endocrinology [Category] MERS, SARS, 치료기술, [키워드] affected aggressive course Behavior common factor contagious Control Coronavirus pandemic country Course COVID-19 deficiency distribution Early detection epidemiological Epidemiology females group growth hormone help hormone Human IGF-1 immune system leads life limitation male management morbidity morbidity and mortality observation patient groups patients planet question raised risk Risk factors role secretion Spread spread to the disease unique virus vulnerability worldwide pandemic Wuhan Wuhan, China [DOI] 10.3389/fendo.2020.569633 PMC 바로가기 [Article Type] Endocrinology
Hepatitis B virus suppresses the secretion of insulin-like growth factor binding protein 1 to facilitate anti-apoptotic IGF-1 effects in HepG2 cellsArticle Published on 2018-09-152023-06-18 Journal: Experimental cell research [Category] B형 간염, [키워드] Apoptosis HBx Hepatitis B virus HepG2 IGF-1 IGFBP1. [DOI] 10.1016/j.yexcr.2018.07.002