Exploring the depths of IgG4: insights into autoimmunity and novel treatmentsImmunology Review Published on 2024-04-182024-09-05 Journal: Frontiers in immunology [Category] update2024, [키워드] antibodies IgG4 IgG4-AID IgG4-RD immunotherapies [DOI] 10.3389/fimmu.2024.1346671 PMC 바로가기 [Article Type] Immunology Review
Exploring the promising potential of induced pluripotent stem cells in cancer research and therapyarticle Published on 2023-11-282024-09-05 Journal: Molecular Cancer [Category] update2024, [키워드] immunotherapies induced pluripotent stem cells Personalized medicine regenerative medicine therapy tumorigenesis [DOI] 10.1186/s12943-023-01873-0 PMC 바로가기 [Article Type] article
Anti-NMDA Receptor Autoimmune Encephalitis: Diagnosis and Management StrategiesReview Published on 2023-01-042024-09-04 Journal: International Journal of General Medicine [Category] 대상포진, [키워드] anti-NMDAR encephalitis Clinical features immunotherapies Treatment options [DOI] 10.2147/IJGM.S397429 PMC 바로가기 [Article Type] Review
Coronavirus disease 2019 subphenotypes and differential treatment response to convalescent plasma in critically ill adults: secondary analyses of a randomized clinical trialArticle Published on 2022-11-012022-11-15 Journal: Intensive care medicine [Category] Fulltext, MERS, 바이오마커, [키워드] ABO-compatible convalescent plasma Adaptive platform trial Adults Analysis assigned Biomarker Biomarkers chemokines community-acquired pneumonia convalescent plasma Convalescent plasma therapy coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patient Critically ill critically ill patients Cytokines difference effector immune responses elevated endothelial explain heterogeneous homogeneous Hypothesis immunologically immunotherapies Inflammation IQR median multifactorial organ support outcome outcomes patients Population precision medicine Prevalence Randomized randomized clinical trial RCT RCTs REMAP-CAP reported secondary analysis Subphenotypes. tested therapy treatment effect Treatment response usual care with COVID-19 [DOI] 10.1007/s00134-022-06869-w PMC 바로가기
Sensitivity to Vaccines, Therapeutic Antibodies, and Viral Entry Inhibitors and Advances To Counter the SARS-CoV-2 Omicron VariantArticle Published on 2022-09-212022-11-15 Journal: Clinical microbiology reviews [Category] COVID19(2023년), SARS, 변종, 유전자 메커니즘, 진단, 치료제, [키워드] acute respiratory syndrome advance antibodies antibody-based therapies booster characterized Community coronavirus counter COVID-19 disease severity driving effective strategy Effectiveness entry inhibitors Entry mechanism enzyme evade faster fusion inhibitors fusion pathway highlighting immune Immune escape immune evasion Immunity immunotherapies Infection inhibitor inhibitors Innate mitigate monoclonal motif mutated natural infection omicron pan-CoV vaccines Perspective raising resistance resulting SARS-CoV-2 SARS-CoV-2 Omicron SARS-CoV-2 variant SARS-CoV-2 viral Spread T cell T cell response the SARS-CoV-2 the spike protein Transmissibility Transmission Vaccine vaccine-induced antibody Vaccines variant variants virus [DOI] 10.1128/cmr.00014-22 PMC 바로가기
Difference in safety and humoral response to mRNA SARS-CoV-2 vaccines in patients with autoimmune neurological disorders: the ANCOVAX study자가면역 신경계 장애 환자에서 mRNA SARS-CoV-2 백신에 대한 안전성 및 체액 반응의 차이: ANCOVAX 연구Article Published on 2022-08-012022-09-11 Journal: Journal of Neurology [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술, [키워드] 95% CI ANC anti-CD20 anti-SARS-CoV-2 anti-SARS-CoV-2 IgG Anti-spike antibody antibody levels Antibody Response Assessing Autoimmune Autoimmune neurological disorders BNT162b2 BNT162b2 vaccine Clinical practice condition Control difference dose Effect evaluated fingolimod humoral Humoral response IgG immune therapy immunotherapies Immunotherapy incidence increased risk IQR Local longitudinal study mAb median age mRNA mRNA vaccine mRNA vaccines mRNA-1273 mRNA-1273 vaccine Multiple multiple sclerosis neurological Neurological status not different of BNT162b2 Patient patients rate ratio Receptor binding domain reduced Relapse Safe SARS-CoV-2 SARS-CoV-2 vaccine Sars-Cov2-mRNA vaccine. second dose seroconversion rate side Side effects systemic reaction systemic reactions the antibody response Treatment vaccination Vaccine were assessed [DOI] 10.1007/s00415-022-11142-7 PMC 바로가기 [Article Type] Article
Emergence of SARS-CoV-2 Omicron (B.1.1.529) variant, salient features, high global health concerns and strategies to counter it amid ongoing COVID-19 pandemicSARS-CoV-2 오미크론(B.1.1.529) 변종, 두드러진 특징, 높은 전 세계 건강 문제 및 진행중인 COVID-19 대유행 속에서 이에 대응하기 위한 전략의 출현Review Published on 2022-06-012022-09-11 Journal: Environmental research [Category] COVID19(2023년), MERS, SARS, 변종, 유전자 메커니즘, 진단, [키워드] accumulation Alpha Analysis animals appearance approach B.1.1.529 Beta booster doses China COVID-19 pandemic Delta Delta variants Diagnosis Efficacy emergence evade Evolution explain Features Gamma generate Genome genome analysis Health humans Immune escape immune pressure Immunity immunotherapies Immunotherapy implementation Infection late less lethality long term measure multivalent vaccine mutated Mutation mutation rate Mutation rates natural infection omicron Omicron origin patients persistence pre-existing immunity prevention Prevention and control raising receiving SARS-CoV-2 SARS-CoV-2 pandemic Spike protein the spike protein Therapies vaccination Vaccine Vaccine failure Vaccines variant variant of concern variants virus VoC [DOI] 10.1016/j.envres.2022.112816 PMC 바로가기 [Article Type] Review
γδ T Cells in Emerging Viral Infection: An Overview신종 바이러스 감염의 γδ T 세포: 개요Review Published on 2022-05-272022-09-11 Journal: Viruses [Category] COVID19(2023년), SARS, 치료제, [키워드] acquired immunity acute respiratory syndrome acute respiratory syndrome coronavirus analyzed Antiviral antiviral activity Cancer cellular China contributing to Coronaviridae Coronavirus-2 Coronaviruses cytolytic example Features Filoviridae filoviruses Flaviviridae flaviviruses gammadelta T cells Health health problem Host Immunity immunotherapies Immunotherapy Innate immunity intestines lung Lungs mechanism microbes MONITOR New pandemic pathogen pleiotropic profile PROTECT protective immune response public health public health authorities SARS-CoV-2 Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus-2 skin Spread Surveillance T cell T cells target the Coronaviridae threat tissues to define Transmission viral infection viral infections virus viruses [DOI] 10.3390/v14061166 PMC 바로가기 [Article Type] Review
Robust temporal map of human in vitro myelopoiesis using single-cell genomics Research Published on 2022-05-242022-10-05 Journal: Nature Communications [Category] 유전자 메커니즘, [키워드] Cell dendritic cell described develop Effect feature fetal generate Hematopoiesis Hematopoietic stem cell homeostasis Immunity immunotherapies imperative in vitro in vivo integration lineages Macrophage macrophages mast cell molecular Monocytes myeloid myeloid cell pluripotent stem cell protocol Regulatory Research resource single-cell single-cell genomics therapeutic transcription factor [DOI] 10.1038/s41467-022-30557-4 [Article Type] Research
Evaluating performance of existing computational models in predicting CD8+ T cell pathogenic epitopes and cancer neoantigensCD8+ T 세포 병원성 에피토프 및 암 신생항원 예측에서 기존 컴퓨터 모델의 성능 평가Article Published on 2022-05-132022-09-12 Journal: Briefings in Bioinformatics [Category] MERS, 진단, [키워드] acute respiratory syndrome binding affinity Cancer cancer neoantigen cancers CD8 T-cell CD8 T-cell target CD8+ T cell coronavirus disease distribution epitope evaluated Evaluating Evidence facilitate Factor feature highlight histocompatibility complex HLA ligand immunogenic immunogenic peptide immunotherapies Immunotherapy Intensive long-term immune responses malignant cell modulate offer parameter pathogen pathogenic pathology peptide peptide immunogenicity peptide presentation peptides predictors question random Research robust stability suggested T cell T cell receptor T-cell T-cell Response target threshold training data Vaccine Variation virus [DOI] 10.1093/bib/bbac141 PMC 바로가기 [Article Type] Article