A Comprehensive Insight and In Silico Analysis of CircRNAs in Hepatocellular Carcinoma: A Step toward ncRNA-Based Precision MedicineReview Published on 2024-07-242024-09-05 Journal: Cells [Category] update2024, [키워드] bioinformatics circRNAs epigenetics HCC in silico Initiation Metastasis ncRNA progression theranostics [DOI] 10.3390/cells13151245 PMC 바로가기 [Article Type] Review
Optimal Timing of Remdesivir Initiation in Hospitalized Patients With Coronavirus Disease 2019 (COVID-19) Administered With Dexamethasone덱사메타손을 투여한 2019 코로나바이러스 질환(COVID-19) 입원 환자에서 렘데시비르 시작의 최적 시기Article Published on 2022-08-242022-09-12 Journal: Clinical Infectious Diseases: An Official Publicat [Category] SARS, 진단, [키워드] 95% CI acute respiratory distress addition applied benefit Clinical improvement Cohort coronavirus disease COVID-19 Cox regression models cumulative Dexamethasone difference drug exposure group Follow-up group hazard ratio Hong Kong hospital Hospital stay Hospitalization Hospitalized HRs IgG antibody In-hospital death increased risk initiated Initiation Length of hospital stay lower risk Multiple outcome Patient patients with moderate positive Probability progression Remdesivir significantly shorter Survivors syndrome time time to clinical improvement. Treatment Weighting were given WHO [DOI] 10.1093/cid/ciab728 PMC 바로가기 [Article Type] Article
Sustained Impact of the Coronavirus Disease 2019 Pandemic on Hepatitis C Virus Treatment Initiations in the United States미국의 C형 간염 바이러스 치료 시작에 대한 코로나바이러스 질병 2019 대유행의 지속적인 영향Article Published on 2022-08-242022-09-12 Journal: Clinical Infectious Diseases: An Official Publicat [Category] 진단, [키워드] age and gender antibody Antibody testing coronavirus coronavirus disease COVID-19 COVID-19 pandemic Decline dropped fixed Genotype HCV HCV antibody healthcare providers Hepatitis hepatitis C hepatitis C virus Impact indicated Initiation National Patient performed Poisson regression model random intercept recent reduction regression analysis remained RNA significant increases in starting stratified Testing the United State Treatment treatment initiation Volume [DOI] 10.1093/cid/ciac175 PMC 바로가기 [Article Type] Article
Clinical Effect of Early administration of Tocilizumab Following the Initiation of Corticosteroid Therapy for Patients with COVID-19Article Published on 2022-08-012022-10-05 Journal: Journal of infection and chemotherapy : official j [Category] COVID19(2023년), SARS, 임상, 진단, 치료기술, [키워드] acute respiratory syndrome addition administration analyzed baseline blood cell count C-reactive protein caused clinical Clinical characteristics combination therapy coronavirus Corticosteroid corticosteroid therapy corticosteroid treatment Corticosteroids COVID-19 determine drug early administration Effect effective Efficacy evaluated global pandemic groups hospital Hospitalized Initiation maximum body temperature not significantly different oxygen-free day Patient patients with COVID-19 Result SARS-CoV-2 significant decrease significantly higher significantly lower significantly more survival rate Tocilizumab tocilizumab administration treated treating COVID-19 two groups white with COVID-19 Wuhan [DOI] 10.1016/j.jiac.2022.08.021 [Article Type] Article
The Impact of COVID-19 on the Initiation of Clinical Trials in Europe and the United StatesCOVID-19가 유럽과 미국의 임상 시험 시작에 미치는 영향Article Published on 2022-05-012022-09-11 Journal: Clinical Pharmacology and Therapeutics [Category] 임상, [키워드] affected Analysis analyzed average clinical clinical trial clinical trials conducted coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 pandemic daily living decrease EU Clinical Trial Europe Impact increase in initiated Initiation less Non-COVID-19 pandemic public health reached reduced regions remained the United State The United States Trial trials United States [DOI] 10.1002/cpt.2534 PMC 바로가기 [Article Type] Article
Emerging Socioeconomic Disparities in COVID-19 Vaccine Second-Dose Completion Rates in the United StatesCommunication Published on 2022-01-142022-10-28 Journal: Vaccines [Category] COVID-19, [키워드] accounting age association calculated Complete completion COVID-19 COVID-19 vaccination demographics difference disparity equity future infection Health disparities individual Inequity initiated Initiation Logistic regression multi-dose vaccines observé Rate response the United State The United States vaccination Vaccine [DOI] 10.3390/vaccines10010121 PMC 바로가기 [Article Type] Communication
Interleukin-37: A Link Between COVID-19, Diabetes, and the Black FungusMicrobiology Published on 2022-01-132022-10-31 Journal: Frontiers in Microbiology [Category] COVID-19, [키워드] black Comorbidity coronavirus disease Corticosteroids COVID-19 COVID-19 pandemic COVID-19 patients cytokine diabete diabetes Diabetic dysregulated immune response Fungal infection fungus hospitals IL-1 IL-37 immune responses Infection Inflammation Initiation invasive involved lack lower mortality Mucormycosis oxygen Patient reduce reducing secondary infections severe COVID-19 systemic corticosteroid T2D use of corticosteroid [DOI] 10.3389/fmicb.2021.788741 PMC 바로가기 [Article Type] Microbiology
Utilizing Telemedicine and Modified Fibrosis Staging Protocols to Maintain Treatment Initiation and Adherence Among Hepatitis C Patients During the COVID-19 PandemicCOVID-19 팬데믹 기간 동안 C형 간염 환자의 치료 시작 및 순응도를 유지하기 위해 원격 진료 및 수정된 섬유증 병기 프로토콜 활용Article Published on 2022-01-012022-09-11 Journal: Journal of primary care & community health [Category] 치료제, [키워드] Access to care adherence appointments Blood blood test Boston Care center clinics cohorts of patient Community community health controls COVID COVID-19 COVID-19 pandemic decrease Effectiveness exacerbated fibrosis group HCV healthcare hepatitis C hepatitis C virus initial initiated Initiation lab lack lifted lockdown lockdowns mail medication mitigate outcome P -value pandemic Patient prevention primary care proportions retrospective cohort study staging Support sustained t -test Telemedicine the patient Treatment underserved communities. variable [DOI] 10.1177/21501319221108000 PMC 바로가기 [Article Type] Article
Comparative Safety and Efficacy of Remdesivir Versus Remdesivir Plus Convalescent Plasma Therapy (CPT) and the Effect of Timing of Initiation of Remdesivir in COVID-19 Patients: An Observational Study From North East IndiaEmergency Medicine Published on 2021-11-282022-10-31 Journal: Cureus [Category] COVID-19, [키워드] addition age analyzed baseline baseline characteristics category clinical benefit Combination comparable Comparative conducted Convalescent plasma therapy COVID-19 COVID-19 treatment guideline Disease progression disease severity East Effect Efficacy evaluated ferritin follow up group Hospitalized ICU India indicated Initiation lack liver function tests material mechanical ventilation moderate Mortality national guidelines North observation outcome parameter Patient Population Prognostic factor proportion Remdesivir response to therapy Result Safety serum creatinine severe COVID-19 severe COVID-19 patient severe patients severity Sex Shortness of breath SpO2 subsequent symptom onset therapeutic treated Treatment outcome Ventilation [DOI] 10.7759/cureus.19976 PMC 바로가기 [Article Type] Emergency Medicine
Virtual reality for relatives of ICU patients to improve psychological sequelae: study protocol for a multicentre, randomised controlled trial심리적 후유증을 개선하기 위한 ICU 환자의 친척을 위한 가상 현실: 다기관, 무작위 대조 시험을 위한 연구 프로토콜Article Published on 2021-09-282022-09-11 Journal: BMJ Open [Category] SARS, 임상, [키워드] 1:1 Admission adult intensive & approval approved can not Care clinical trials conducted control group COVID-19 Critical Critical care difficulty discharge distress effective interventions Erasmus Ethics ethics committee expected family grief hospital hypothesised ICU ICU patient ICU treatment IMPROVE include increase information Information provision Initiation Intensive intensive & intensive care unit Intervention intervention group life Local mental health multicentre Netherland Netherlands participant Patient peer-reviewed Psychological Psychological distress Psychological well-being Quality of life randomised randomised controlled trial REALITY receive registration number relative resulting risk secondary outcome Study protocol the patient Trial usual care virtual reality was obtained [DOI] 10.1136/bmjopen-2021-049704 PMC 바로가기 [Article Type] Article