Antibody Response in Immunocompromised Patients After the Administration of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Vaccine BNT162b2 or mRNA-1273: A Randomized Controlled Trial중증급성호흡기증후군 코로나바이러스 2(SARS-CoV-2) 백신 BNT162b2 또는 mRNA-1273 투여 후 면역저하 환자의 항체 반응: 무작위 대조 시험Randomized Controlled Trial Published on 2022-08-242022-09-12 Journal: Clinical Infectious Diseases: An Official Publicat [Category] SARS, 임상, 진단, [키워드] 1:1 95% confidence interval acute respiratory syndrome addition Antibody Response BNT162b2 Cohort Controlled coronavirus coronavirus 2 Cutoff Efficacy Elecsy first vaccination had no HIV Human immunodeficiency virus immune response immunoassay Immunocompromised patient Immunocompromised patients infections intention-to-treat analysis kidney lung Moderna mRNA-1273 Open-label organ Organ transplant Patient Pfizer-BioNTech platform Platform trial PLWH Prevent primary endpoint proportion Protein Randomized randomized clinical trial Randomized controlled trial Receptor binding domain recipient respiratory response SARS-CoV-2 SARS-CoV-2 spike second vaccination solid organ transplant the antibody response Transplant Vaccine was measured [DOI] 10.1093/cid/ciac169 PMC 바로가기 [Article Type] Randomized Controlled Trial
Effectiveness and adherence to closed face shields in the prevention of COVID-19 transmission: a non-inferiority randomized controlled trial in a middle-income setting (COVPROSHIELD)COVID-19 전염 예방에 대한 폐쇄형 안면 보호구의 효과 및 준수: 중간 소득 환경에서의 비열등 무작위 대조 시험(COVPROSHIELD)Randomized Controlled Trial Published on 2022-08-202022-09-11 Journal: Trials [Category] SARS, 임상, 치료기술, [키워드] 95% CI active control group Antibody test assigned benefit Chain Reaction clinical clinical trial Closed face shield combined use Community condition COVID-19 COVID-19 pandemic cross crowding determine disease Effectiveness face Face mask Face masks Face shield Follow-up follow-up period groups highly active IgM antibody inferiority intention-to-treat analysis intervention group limit Mask Masks mitigate non-inferiority Open-label participant per-protocol analysis polymerase chain polymerase chain reaction positive Prevent prevention of COVID-19 Primary outcome Randomized Randomized controlled trial Randomly reverse transcription risk risk difference SARS-CoV-2 SARS-CoV-2 detection SARS-COV-2 infection SARS-CoV-2 test SARS-CoV-2 transmission setting Spread surgical test result two groups Ventilation Viral transmission [DOI] 10.1186/s13063-022-06606-0 PMC 바로가기 [Article Type] Randomized Controlled Trial
Evaluating the effectiveness of a 6-week hybrid mindfulness-based intervention in reducing the stress among caregivers of patients with dementia during COVID-19 pandemic: protocol of a randomized controlled trialCOVID-19 대유행 기간 동안 치매 환자 간병인의 스트레스 감소에 대한 6주 하이브리드 마음챙김 기반 개입의 효과 평가: 무작위 대조 시험 프로토콜Article Published on 2022-07-192022-09-11 Journal: BMC Psychology [Category] 임상, [키워드] 1:1 Analysis approach attrition benefit Care Caregiver Caregivers component conducted control group control groups Controlled trial COVID-19 COVID-19 pandemic Dementia Effect Effectiveness Eligible participants equation evaluate Evaluating Face-to-face Follow-up follow-up period Frequency Generalized heart rate identify intention-to-treat analysis Intervention intervention group introduced limitations Local Mindfulness-based Neuropsychiatric Online organization Other outcomes outcome parallel-group participant Participants Patient physiological protocol public health qualitative data Quantitative Quantitative data Randomized controlled trial randomly divided RCT receive reducing Research researcher shown Social distancing measure social distancing measures Stress Symptoms therapeutic viability Well-being [DOI] 10.1186/s40359-022-00876-8 PMC 바로가기 [Article Type] Article
The Impact of Telephone-Based Cognitive Behavioral Therapy on Mental Health Distress and Disordered Eating Among Bariatric Surgery Patients During COVID-19: Preliminary Results from a Multisite Randomized Controlled TrialRandomized Controlled Trial Published on 2022-06-012022-10-05 Journal: Obesity surgery [Category] Coronavirus, 임상, [키워드] 1:1 age Anxiety baseline Care China cognitive Comorbidity control group Controlled COVID-19 COVID-19 pandemic depressive determine Discipline Discipline and resistance Disordered disordered eating eating Effect effective Efficacy Exacerbation feasible female Follow-up Foucault GAD-7 Generalized group Impact intention-to-treat analysis Interaction Intervention intervention group management mental health distress Online compulsory education. outcome participant Patient PHQ-9 post-intervention Psychiatric Psychological distress Quality of life Randomized Randomized controlled trial receive recruited Result scale significant decrease significant difference surgery Symptom therapy Treatment were measured were used [DOI] 10.1007/s11695-022-05981-6 PMC 바로가기 [Article Type] Randomized Controlled Trial
Efficacy and Safety of Vitamin D Supplementation to Prevent COVID-19 in Frontline Healthcare Workers. A Randomized Clinical TrialRandomized Controlled Trial Published on 2022-06-012022-10-04 Journal: Archives of medical research [Category] COVID19(2023년), SARS, 임상, [키워드] 25-hydroxyvitamin D3 adverse event Antibody test assigned baseline clinical conducted COVID-19 cross-sectional deficiency determine double-blind Efficacy and safety enrolled Follow-up healthcare worker Healthcare workers hospital individual individuals intention-to-treat analysis manifestation Mexico City participant patients with moderate Placebo Prevent randomized trial Randomly receive recruited subjects repeated risk RT-PCR test Safety SARS-CoV-2 SARS-COV-2 infection serious AE Serum level severe COVID-19 tested Vitamin D were measured [DOI] 10.1016/j.arcmed.2022.04.003 PMC 바로가기 [Article Type] Randomized Controlled Trial
TTCOV19: timing of tracheotomy in SARS-CoV-2-infected patients: a multicentre, single-blinded, randomized, controlled trialRandomized Controlled Trial Published on 2022-05-182022-10-05 Journal: Critical Care [Category] COVID19(2023년), SARS, 임상, [키워드] 95% CI acute respiratory distress adverse events age assigned Complication correlation COVID-19 COVID-19 patient Critically ill patient death rate develop evaluate Götaland group groups intensive care intention-to-treat analysis intubation IQR males Mechanical mechanical respiratory mechanical ventilation median multicentre no significant difference observational study Patient per-protocol analysis protocol Randomized controlled trial randomized, controlled trial Randomly reduced Region Registered Respiratory Support SARS-CoV-2-infected patient selected significantly Spearman suggested Support survival syndrome the timing time Time factors tracheotomy treatment regimen with COVID-19 [DOI] 10.1186/s13054-022-04005-0 PMC 바로가기 [Article Type] Randomized Controlled Trial
Foot–ankle therapeutic exercise program can improve gait speed in people with diabetic neuropathy: a randomized controlled trial Research Published on 2022-05-092022-10-05 Journal: Scientific Reports [Category] 임상, [키워드] complementary Control control group controls determine Diabetic functional gait speed group IMPROVE intention-to-treat analysis intervention group Musculoskeletal Participants physical activity Primary outcome Quality of life Randomized controlled trial remained Secondary outcomes significantly single-blind therapeutic Treatment usual care Volunteer [DOI] 10.1038/s41598-022-11745-0 [Article Type] Research
Early prolonged prone position in noninvasively ventilated patients with SARS-CoV-2-related moderate-to-severe hypoxemic respiratory failure: clinical outcomes and mechanisms for treatment response in the PRO-NIV studyControlled Clinical Trial Published on 2022-04-292022-10-04 Journal: Critical Care [Category] COVID19(2023년), SARS, 임상, [키워드] 95% CI Admission Adverse age Analysis baseline Biomarker category changes circulating clinical Clinical outcome CO2 consecutive patient Control controls Corrected minute ventilation COVID-19 D-dimer dead Dead space death death rate enrolled evaluated event Hypoxemia hypoxemic IMPROVE Inflammatory Inflammatory marker initial intention-to-treat analysis intubation limit lung Lung Ultrasonography Lung ultrasound mechanism mortality risk NIV non-randomized trial Noninvasive ventilation occurred Oxygenation parameters Patient patients with COVID-19 physiological physiological mechanism Pneumonia predicted Prone position reduced reduction Region regions Registered remained Respiratory failure Safe severity study population therapy treated Treatment response Trial unit variable ventilated patient Ventilatory ratio was performed with COVID-19 [DOI] 10.1186/s13054-022-03937-x PMC 바로가기 [Article Type] Controlled Clinical Trial
The effects of text reminders on the use of family planning services: evidence from a randomised controlled trial in urban MozambiqueRandomized Controlled Trial Published on 2022-04-012022-10-05 Journal: BMJ Global Health [Category] 임상, [키워드] Analysis assigned Community conducted Contraception contraceptive method control arm Effect enrolled Evidence family Final Follow-up Health health worker include increase individual Individual randomized trial intention-to-treat analysis outcomes Planning Population Probability Program provided Public public health Randomised control trial. randomised controlled trial Randomized Randomly receive reported risk service statistically significant text reminder treatment group Trial unmet need women [DOI] 10.1136/bmjgh-2021-007862 PMC 바로가기 [Article Type] Randomized Controlled Trial
Intravenous immunoglobulins in patients with COVID-19-associated moderate-to-severe acute respiratory distress syndrome (ICAR): multicentre, double-blind, placebo-controlled, phase 3 trialCOVID-19 관련 중등도에서 중증 급성 호흡 곤란 증후군(ICAR) 환자의 정맥 면역글로불린: 다기관, 이중 맹검, 위약 대조, 3상 시험Clinical Trial Published on 2022-02-012022-09-12 Journal: The Lancet. Respiratory Medicine [Category] COVID19(2023년), MERS, SARS, 임상, 진단, [키워드] 1:1 acute respiratory distress Administered administration adverse event adverse events ARDS Clinique complication of COVID-19 COVID-19 disease stage distress double-blind eligible event for inclusion France Frequency high mortality Immunoglobulin IMPROVE improve clinical outcome Inclusion intention-to-treat analysis intention-to-treat principle Intravenous immunoglobulin Invasive mechanical ventilation Lung injury morbidity multicentre no statistical difference not significant outcome Patient patients patients with COVID-19 PCR phase 3 trial Placebo placebo-controlled placebo-controlled trial Primary outcome Randomly randomly assigned patient receive receiving reducing Registered risk Serious Adverse Events Sodium chloride stratified syndrome the median the placebo group Treatment Trial trials Volume was done web-based system women [DOI] 10.1016/S2213-2600(21)00440-9 PMC 바로가기 [Article Type] Clinical Trial