The Impact of Serum/Plasma Proteomics on SARS-CoV-2 Diagnosis and PrognosisReview Published on 2024-08-082024-09-05 Journal: International Journal of Molecular Sciences [Category] update2024, [키워드] COVID-19 LC-MS Multi-omics plasma proteomics serum [DOI] 10.3390/ijms25168633 PMC 바로가기 [Article Type] Review
Cross-Validation of Metabolic Phenotypes in SARS-CoV-2 Infected Subpopulations Using Targeted Liquid Chromatography–Mass Spectrometry (LC-MS)article Published on 2024-03-142024-09-05 Journal: Journal of Proteome Research [Category] update2024, [키워드] bile acids COVID-19 hypoxia LC-MS metabolic phenotyping metabolic phenotyping array Organic acids oxidative stress SARS-CoV-2 TCA cycle validation [DOI] 10.1021/acs.jproteome.3c00797 PMC 바로가기 [Article Type] article
Duck hepatitis A virus type 1 infection induces hepatic metabolite and gut microbiota changes in ducklingsIMMUNOLOGY, HEALTH AND DISEASE Published on 2023-11-052024-09-05 Journal: Poultry Science [Category] update2024, [키워드] 16S rDNA DHAV-1 gut microbiota LC-MS liver metabolomics [DOI] 10.1016/j.psj.2023.103265 PMC 바로가기 [Article Type] IMMUNOLOGY, HEALTH AND DISEASE
Push forward LC-MS-based therapeutic drug monitoring and pharmacometabolomics for anti-tuberculosis precision dosing and comprehensive clinical managementReview Paper Published on 2023-09-222024-09-05 Journal: Journal of Pharmaceutical Analysis [Category] update2024, [키워드] LC-MS MIPD Pharmacometabolomics precision medicine Therapeutic Drug Monitoring Tuberculosis [DOI] 10.1016/j.jpha.2023.09.009 PMC 바로가기 [Article Type] Review Paper
Understanding common population markers for SARS-CoV-2 RNA normalization in wastewater – A reviewArticle Published on 2023-05-162024-09-05 Journal: Chemosphere [Category] update2024, [키워드] Chemical indicator extraction GC-MS LC-MS Population biomarker wastewater Wastewater parameter [DOI] 10.1016/j.chemosphere.2023.138682 PMC 바로가기 [Article Type] Article
Development and Validation of an Innovative Analytical Approach for the Quantitation of Tris(Hydroxymethyl)Aminomethane (TRIS) in Pharmaceutical Formulations by Liquid Chromatography Tandem Mass SpectrometryArticle Published on 2022-12-222023-07-11 Journal: Molecules [Category] COVID19(2023년), [키워드] COVID-19 vaccine derivatization GMP isobutyl chloroformate LC-MS Pharmaceuticals quantitation tris tromethamine validation [DOI] 10.3390/molecules28010073 PMC 바로가기
Derivation, Functionalization of (S)-Goniothalamin from Goniothalamus wightii and Their Derivative Targets SARS-CoV-2 MPro, SPro, and RdRp: A Pharmacological PerspectiveArticle Published on 2022-10-172022-11-15 Journal: Molecules [Category] COVID19(2023년), SARS, 치료제, [키워드] (S)-Goniothalamin Anti-viral anticancer antioxidant antiviral properties antiviral property approach characterization complex Compound coronavirus COVID-19 derivation derivative disease drug examined LC-MS molecular molecular dynamics MPro NMR pandemic performed phytochemical platform Pro RdRP required Research SARS-CoV-2 SARS-COV-2 infection Simulation study spike glycoprotein target target protein threat [DOI] 10.3390/molecules27206962 PMC 바로가기
t6A and ms2t6A Modified Nucleosides in Serum and Urine as Strong Candidate Biomarkers of COVID-19 Infection and SeverityArticle Published on 2022-09-032022-11-15 Journal: Biomolecules [Category] SARS, 바이오마커, 변종, [키워드] addition Alter Biomarker candidate cellular RNA changes in COVID-19 COVID-19 infection COVID-19 patient COVID-19 patients elevated Extracellular Infection LC-MS modified nucleosides. nucleoside nucleosides RNA SARS-CoV-2 searched serum severity Strong symptom severity Urine variants [DOI] 10.3390/biom12091233 PMC 바로가기
Proteomic Profile of Procoagulant Extracellular Vesicles Reflects Complement System Activation and Platelet Hyperreactivity of Patients with Severe COVID-19응고촉진 세포외 소포의 단백질 프로파일은 중증 COVID-19 환자의 보체 시스템 활성화 및 혈소판 과민반응을 반영합니다Article Published on 2022-07-222022-09-11 Journal: Frontiers in Cellular and Infection Microbiology [Category] COVID19(2023년), SARS, 유전자 메커니즘, [키워드] acute inflammatory response alteration analyzed applied approach biological processe biological processes Biomarker Biomarkers cascades caused change changes in circulating Coagulation complement complement factors computational analysis COVID-19 COVID-19 patients Cytometry degranulation disease pathogenesis Diseases EVs experiment expressed extracellular vesicle Extracellular vesicles Flow flow cytometry group healthy donor healthy donors identify increase in indicated infected with SARS-CoV-2 LC-MS LC-MS/MS molecular pathophysiological Patient plasma Platelet Platelets procoagulant procoagulant activity profile progression Protein proteome proteomic SARS-CoV-2 SEC severe COVID-19 severe COVID-19 patients severity of COVID-19 significant changes in size exclusion chromatography System the disease tissue Tissue Factor total protein Vesicle was performed [DOI] 10.3389/fcimb.2022.926352 PMC 바로가기 [Article Type] Article
Diagnosis and prognosis of COVID-19 employing analysis of patients’ plasma and serum via LC-MS and machine learningLC-MS 및 머신러닝을 통한 환자의 혈장 및 혈청 분석을 통한 코로나19 진단 및 예후Article Published on 2022-07-012022-09-11 Journal: Computers in biology and medicine [Category] COVID19(2023년), MERS, SARS, 바이오마커, 변종, 진단, 치료기술, [키워드] Accuracy acetyl Algorithm Analysis analyzed best Biomarker Biomarkers caused China controls COVID COVID 19 COVID-19 COVID-19 diagnosis COVID-19 patient datasets Diagnosis evaluate evaluated fatality glucosamine greater healthy volunteer healthy volunteers help hospital independent l-ornithine LC-MS machine machine learning material metabolite methyl isobutyrate negative RT-PCR outcomes Patient patients with COVID-19 patients with pneumonia phosphate plasma Pneumonia predict Prognosis prognostic indicator RT-PCR Sample SARS-CoV-2 serum severity significantly SVM the disease uridine virus viruses were used with COVID-19 [DOI] 10.1016/j.compbiomed.2022.105659 PMC 바로가기 [Article Type] Article