Electrochemical paper-based antigen sensing platform using plant-derived monoclonal antibody for detecting SARS-CoV-2Article Published on 2023-01-012022-11-15 Journal: Talanta [Category] SARS, 진단, 치료기술, 치료제, [키워드] anti-SARS-CoV-2 antibody Antigen applicability applied approach Cellulose Concentration COVID-19 diagnosis CR3022 detect diagnostic Differential pulse voltammetry expressed functional group limit of detection linear relationship monoclonal antibody nasopharyngeal swab sample Nicotiana benthamiana Paper-based electrochemical immunosensor Plant-based antibody platform point-of-care pulse quantification RBD Receptor binding domain Saliva SAR-CoV-2 SARS-CoV-2 SARS-COV-2 infection Spike protein the RBD this system was performed [DOI] 10.1016/j.talanta.2022.123783 PMC 바로가기
A quantitative RT-qLAMP for the detection of SARS-CoV-2 and human gene in clinical applicationArticle Published on 2022-10-012022-11-16 Journal: Microbial Biotechnology [Category] COVID19(2023년), SARS, 변종, 치료기술, [키워드] applied BBIBP-CorV Beta clinical sample clinical samples Clinical treatment cycle threshold Delta demonstrated detect evaluate evaluated fluorescent full-length help human gene inactivated isothermal isothermal amplification linear linear relationship management omicron pandemic Patient physician positive qPCR Quantitative required RNA RT-qPCR SARS-CoV-2 swab samples threshold Transcription variants of SARS-CoV-2 Viral load viral loads viral particle was used [DOI] 10.1111/1751-7915.14112 PMC 바로가기
An electrochemical aptasensor with N protein binding aptamer-complementary oligonucleotide as probe for ultra-sensitive detection of COVID-19N 단백질 결합 앱타머-상보성 올리고뉴클레오티드를 COVID-19의 초고감도 검출을 위한 프로브로 사용하는 전기화학적 앱타센서Article Published on 2022-10-012022-09-11 Journal: Biosensors & bioelectronics [Category] 치료기술, 치료제, [키워드] affected applied aptamer binding blood sample Blood samples changes in complementary Complementary DNA Concentration conformational COVID-19 COVID-19 epidemic COVID-19 in patients DNA double-stranded Early detection effective Electrochemical aptasensor gold hybridization Incubation linear relationship log logarithm N protein N protein detection probe R 2 Rapid Rapid COVID-19 diagnosis Regenerable aptamer sensor. reported sensor solution target the N protein throat swab throat swabs vaccination volunteers was measured [DOI] 10.1016/j.bios.2022.114436 PMC 바로가기 [Article Type] Article
A paper-based optical sensor for the screening of viruses through the cysteine residues of their surface proteins: A proof of concept on the detection of coronavirus infection표면 단백질의 시스테인 잔기를 통한 바이러스 스크리닝을 위한 종이 기반 광학 센서: 코로나바이러스 감염 감지에 대한 개념 증명Article Published on 2022-10-012022-09-11 Journal: Talanta [Category] COVID19(2023년), SARS, 치료기술, 치료제, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus BENZOTHIAZOLE Biothiol cause Chain Reaction clinical study Colorimetric assay complex Concentration coronavirus Coronavirus infection current cysteine cysteine residue Disulfide disulfide bond Filter Paper group Health Human immunodeficiency virus human Papilloma virus immunodeficiency intensity lab lack limit of detection linear relationship logarithm lowest naked eye nasopharyngeal swabs optical pandemic paper Paper based sensor papilloma pathology Patient pink color polymerase chain polymerase chain reaction proof proof of concept Protein Proteins qRT-PCR Rapid reduced required reverse transcription reverse transcription polymerase chain reaction S1 protein Saliva SARS-CoV-2 screening method severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 specimens Spike protein subunit sulfhydryl the S1 protein time-consuming virus viruses [DOI] 10.1016/j.talanta.2022.123630 PMC 바로가기 [Article Type] Article
Are higher antibody levels against seasonal human coronaviruses associated with a more robust humoral immune response after SARS-CoV-2 vaccination?Article Published on 2022-09-082022-11-15 Journal: Frontiers in Immunology [Category] SARS, 진단, [키워드] adjusted affected age anti-spike antibodies anti-spike antibody anti-Spike IgG anti-spike IgG antibodies Anti-spike IgG antibody antibodies antibody Antibody concentrations antigens appear association baseline Blood Canada coronavirus Correlation analysis COVID-19 COVID-19 infection COVID-19 testing demonstrated determine Endemic HCoV-229E HCoV-HKU1 HCoV-NL63 HCoV-OC43 human coronavirus human endemic coronaviruses humoral immune response IgG levels Immunity include increases in linear relationship Multiple regression multiple regression model not affect Observational cohort study participant Participants performed positive provided questionnaire data robust Sample SARS-CoV-2 SARS-CoV-2 antibodies SARS-CoV-2 vaccines Scatter plot significant difference significantly higher tested vaccinated individual vaccination [DOI] 10.3389/fimmu.2022.954093 PMC 바로가기
SARS-CoV-2 virus label-free electrochemical nanohybrid MIP-aptasensor based on Ni 3(BTC) 2 MOF as a high-performance surface substrate고성능 표면 기판으로 Ni 3(BTC) 2 MOF 기반 SARS-CoV-2 바이러스 표지 없는 전기화학 나노하이브리드 MIP-aptasensorArticle Published on 2022-07-192022-09-11 Journal: Mikrochimica Acta [Category] COVID19(2023년), SARS, 치료기술, [키워드] aptamer BTC carbon Concentration Detection limit Dopamine electrochemical biosensor facilitated growth In situ Ni3(BTC)2 MOF increase in linear relationship MIP MOF molecular Molecularly imprinted polymer Polymer S protein SARS-CoV-2 SARS-CoV-2 S SARS-CoV-2 S protein SARS-CoV-2 virus SARS-CoV-2, covid 19. Screen selective the SARS-CoV-2 virus transfer virus [DOI] 10.1007/s00604-022-05357-8 PMC 바로가기 [Article Type] Article
IgG Anti-Spike Antibodies and Surrogate Neutralizing Antibody Levels Decline Faster 3 to 10 Months After BNT162b2 Vaccination Than After SARS-CoV-2 Infection in Healthcare WorkersIgG 항스파이크 항체 및 대리 중화 항체 수준은 의료 종사자의 SARS-CoV-2 감염 후보다 BNT162b2 백신 접종 후 3~10개월 더 빠르게 감소합니다Article Published on 2022-06-152022-09-11 Journal: Frontiers in Immunology [Category] COVID19(2023년), MERS, SARS, 변종, 진단, [키워드] ACE-2 anti-S Anti-spike antibody Antibody titers Beta Beta variant binding BNT162b2 Cohort concern COVD-19 COVD-19 serological testing COVID-19 Decline dose expressed faster HCW Health care Health care worker health care workers highest humoral immune response hybrid IgG Immunity Infection Level linear linear relationship Live virus Month natural infection neutralization Neutralizing Neutralizing activity Neutralizing antibodies neutralizing antibody Neutralizing antibody titer neutralizing antibody titers of BNT162b2 omicron predicted Randomly ranged reduced resulting SARS-CoV-2 SARS-COV-2 infection selected sensitivity serological Serological testing spike surrogate the strongest Type vaccination variant VoC wild type worker [DOI] 10.3389/fimmu.2022.909910 PMC 바로가기 [Article Type] Article
Establishment of the first Chinese national standard for protein subunit SARS-CoV-2 vaccine중국 최초의 단백질 소단위 SARS-CoV-2 백신 국가표준 제정Article Published on 2022-03-252022-09-11 Journal: Vaccine [Category] COVID19(2023년), SARS, 치료기술, 치료제, [키워드] accelerated addition Antigen Antigen content approved asked assigned Biological Biological product calibration China Chinese Committee contribute Control COVID-19 Degradation detect determined by drug ELISA enzyme-linked immunosorbent enzyme-linked immunosorbent assay exhibited expression food house Laboratory linear relationship National national standard potency produced product Protein subunit Quality control reference material reference standard Reference standards returned SARS-CoV-2 SARS-CoV-2 vaccine SARS-CoV-2 vaccines stability target proteins Vaccine was performed [DOI] 10.1016/j.vaccine.2022.02.048 PMC 바로가기 [Article Type] Article
Both simulation and sequencing data reveal coinfections with multiple SARS-CoV-2 variants in the COVID-19 pandemicResearch article Published on 2022-03-182022-10-05 Journal: Computational and Structural Biotechnology Journal [Category] 변종, 유전자 메커니즘, [키워드] accumulations analyses average Betacoronavirus Coinfection index collected COVID-19 case COVID-19 pandemic COVID-19 patient datasets demonstrated GISAID database heterozygous Heterozygous single-nucleotide polymorphisms high mutation rate linear relationship loci nanopore sequencing patients performed polymorphism reported RNA SARS-CoV-2 SARS-CoV-2 genome SARS-CoV-2 lineage SARS-CoV-2 variant SARS-CoV-2 variant coinfection sequencing data single-nucleotide single-stranded SNP SNV Transmissibility transmission route Vaccine variant variants Viral transmission simulation [DOI] 10.1016/j.csbj.2022.03.011 [Article Type] Research article
Assessing acceptance of augmented reality in nursing educationResearch Article Published on 2022-02-172022-10-28 Journal: PLoS ONE [Category] Coronavirus, COVID19(2023년), MERS, SARS, [키워드] Assessing defined determine Health Science hypothese Intention linear relationship negatively affected Non-linear relationship offer pandemic potential benefit Psychological Quantitative Research screening method second tested variable variables was collected was used widespread [DOI] 10.1371/journal.pone.0263937 PMC 바로가기 [Article Type] Research Article