Intersecting Pathways: The Role of Metabolic Dysregulation, Gastrointestinal Microbiome, and Inflammation in Acute Ischemic Stroke Pathogenesis and OutcomesReview Published on 2024-07-212024-09-05 Journal: Journal of Clinical Medicine [Category] update2024, [키워드] acute ischemic stroke adipokines Biomarkers Brain-gut axis Gastrointestinal microbiome Inflammation lipopolysaccharides metabolic dysregulation Neuroinflammation obesity [DOI] 10.3390/jcm13144258 PMC 바로가기 [Article Type] Review
Molecular Mechanisms of Bacterial Resistance to Antimicrobial Peptides in the Modern Era: An Updated ReviewReview Published on 2024-06-212024-09-05 Journal: Microorganisms [Category] update2024, [키워드] antimicrobial peptides antimicrobial resistance bacterial membranes Cationic peptides Efflux pumps host–pathogen interactions lipopolysaccharides molecular resistance mutations peptide modifications [DOI] 10.3390/microorganisms12071259 PMC 바로가기 [Article Type] Review
Designing of multi-epitope peptide vaccine against Acinetobacter baumannii through combined immunoinformatics and protein interaction–based approachesOriginal Article Published on 2023-04-062024-09-05 Journal: Immunologic research [Category] update2024, [키워드] Acinetobacter baumannii immunoinformatics lipopolysaccharides lptD lptE [DOI] 10.1007/s12026-023-09374-4 PMC 바로가기 [Article Type] Original Article
Toward a Shigella Vaccine: Opportunities and Challenges to Fight an Antimicrobial-Resistant Pathogen시겔라 백신을 향하여: 항생제 내성 병원체와 싸우기 위한 기회와 도전Article Published on 2023-02-282024-08-22 Journal: International Journal of Molecular Sciences [Category] 세균성이질, [키워드] AMR lipopolysaccharides O-antigens Shigella type III secretion system Vaccines
The Effect of Mutation in Lipopolysaccharide Biosynthesis on Bacterial Fitness지질다당체 생합성에서의 돌연변이가 세균 적합성에 미치는 영향Article Published on 2022-10-162024-08-22 Journal: Cells [Category] 세균성이질, [키워드] bacterial genome endotoxin lipopolysaccharide biosynthesis lipopolysaccharides Mutation Shigella sonnei 4351
Herbal inhibitors of SARS-CoV-2 M pro effectively ameliorate acute lung injury in miceSARS-CoV-2 M pro의 허브 억제제는 쥐의 급성 폐 손상을 효과적으로 개선합니다Article Published on 2022-06-012022-09-11 Journal: Iubmb Life [Category] COVID19(2023년), SARS, 치료제, [키워드] acute lung injury acute respiratory distress syndrome acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 ALI/ARDS Anti-inflammatory ARDS bacterial lipopolysaccharide cell death China Chinese Compound coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 patients distress effective effective drug effective drugs enzymatic activity functions Herbal identify in vitro in vivo Infectious disease Inhibition assays inhibitors of SARS-CoV-2 lipopolysaccharides Lung injury M pro mice MPro pan-anti-inflammatory protease respiratory distress Respiratory distress syndrome SARS-CoV-2 severe acute respiratory syndrome Coronavirus Spread surface plasmon surface plasmon resonance syndrome the disease Traditional Chinese medicine treating COVID-19 patient Virtual screening virus [DOI] 10.1002/iub.2616 PMC 바로가기 [Article Type] Article
AKR1B10, One of the Triggers of Cytokine Storm in SARS-CoV2 Severe Acute Respiratory SyndromeAKR1B10, SARS-CoV2 중증 급성 호흡기 증후군에서 사이토카인 폭풍의 방아쇠 중 하나Article Published on 2022-02-082022-09-10 Journal: International Journal of Molecular Sciences [Category] COVID19(2023년), MERS, SARS, 유전자 메커니즘, [키워드] Activation Acute respiratory failure AKR1B10 Analysis biological plausibility cell types contribute COVID-19 cytokine Cytokine storm Cytokines died drug treatment enzyme experiment expression extracellular vesicle Extracellular vesicles Factor form gene encoding highlight hospitalised COVID-19 patient hospitalised COVID-19 patients Hypothesis identify IL-1β IL-6 increased expression induce Inflammation inhibitor interleukin interleukin-1β interleukin-6 involved lipopolysaccharides LPS lung lung cells Macrophage macrophages management measurement modulation Occurrence outcomes over-expression Patient pharmacological target Preventing pro-inflammatory pro-inflammatory cytokine pro-inflammatory cytokines Protein reduced reducing Reductase respiratory Respiratory failure SARS-CoV2 secreted sera severe forms of COVID-19 severity significantly storm systemic impact the cytokine storm the disease TNF α TNFα transcriptomic data transferred treated Trigger Tumor tumor necrosis tumor necrosis factor [DOI] 10.3390/ijms23031911 PMC 바로가기 [Article Type] Article
Low-Grade Endotoxemia and Thrombosis in COVID-19COVID-19의 저등급 내독소혈증 및 혈전증Article Published on 2021-06-042022-09-10 Journal: Clinical and Translational Gastroenterology [Category] MERS, SARS, 바이오마커, 치료기술, [키워드] arterial circulation community-acquired pneumonia control subject control subjects controls coronavirus Coronavirus 2019 correlated COVID-19 D-dimer detectable Endotoxemia Follow-up Gut healthy implicated interquartile range lipopolysaccharides Logistic regression analysis LPS marker mechanism median occur Occurrence Patient patients with COVID-19 Pneumonia predicted Registered Serum level serum levels significantly thrombotic Thrombotic complications thrombotic event Thrombotic events Vascular venous [DOI] 10.14309/ctg.0000000000000348 PMC 바로가기 [Article Type] Article
Lipoprotein concentrations over time in the intensive care unit COVID-19 patients: Results from the ApoCOVID study중환자실 COVID-19 환자의 시간 경과에 따른 지단백질 농도: ApoCOVID 연구 결과Research Article Published on 2020-09-242022-08-13 Journal: PLoS ONE [Category] Biochemistry, COVID-19, MERS, SARS, [키워드] acute respiratory syndrome Admission Anti-inflammatory antioxidant association Bacterial Bacterial sepsis bacterial superinfection caused change cholesterol clearance Concentration conducted consecutive patient coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 pneumonia dead patient decrease Diagnosis functions global pandemic HDL HDL-C HDLs High-density lipoprotein High-density lipoproteins Hospitalization Hospitalized ICU ICU admission ICU patient incidence increase in intensive care LDL cholesterol LDL-C lipopolysaccharides lipoprotein Lipoproteins Low-density lipoprotein low-density lipoproteins Mortality neutralize nonsurvivors outcome outcomes Particle Particles Patient pleiotropic Pneumonia profile Prospective Study reference values reported respiratory Result Sepsis Severe COVID-19 pneumonia statistically significant superinfection survival survivor Transport university hospital VAP Ventilator-associated pneumonia were assessed [DOI] 10.1371/journal.pone.0239573 PMC 바로가기 [Article Type] Research Article
Molecular studies of meningococcal and pneumococcal meningitis patients in Ethiopiaarticle Published on 2019-04-302024-09-01 Journal: Innate Immunity [Category] 폐렴구균 감염증, [키워드] bacterial meningitis cerebrospinal fluid chemokine cytokine lipopolysaccharides matrix metallopeptidase-9 Septic shock septicemia [Article Type] article