Effect of IL-6R blockade on plasma lipids and clinical outcomes among hospitalized patients with COVID-19 infectionResearch Article Published on 2024-05-232024-09-05 Journal: Journal of Lipid Research [Category] update2024, [키워드] COVID-19 CRP HDL Inflammation interleukin 6 LDL lipids Lipoproteins monoclonal antibody SARS-CoV-2 triglycerides [DOI] 10.1016/j.jlr.2024.100568 PMC 바로가기 [Article Type] Research Article
Lipidation of pneumococcal proteins enables activation of human antigen-presenting cells and initiation of an adaptive immune responsearticle Published on 2024-04-302024-09-01 Journal: Frontiers in immunology [Category] 폐렴구균 감염증, [키워드] antigen presenting cells dendritic cells immune response lipidation Lipoproteins Streptococcus pneumoniae Vaccine [Article Type] article
Thapsigargin and Tunicamycin Block SARS-CoV-2 Entry into Host Cells via Differential Modulation of Unfolded Protein Response (UPR), AKT Signaling, and ApoptosisArticle Published on 2024-04-302024-09-05 Journal: Cells [Category] update2024, [키워드] Apoptosis ER stress immune response insulin resistance lipid droplets Lipoproteins SARS-CoV-2 thapsigargin Tunicamycin unfolded protein response [DOI] 10.3390/cells13090769 PMC 바로가기 [Article Type] Article
Stratification of Sepsis Patients on Admission into the Intensive Care Unit According to Differential Plasma Metabolic Phenotypesarticle Published on 2024-03-212024-09-05 Journal: Journal of Proteome Research [Category] update2024, [키워드] APACHE diagnostic modeling ICU lipids Lipoproteins mass spectrometry metabolic phenotyping NMR spectroscopy pharmaco-metabonomics plasma IVDr Sepsis Septic shock SPC [DOI] 10.1021/acs.jproteome.3c00803 PMC 바로가기 [Article Type] article
Macrolides Decrease the Proinflammatory Activity of Macrolide-Resistant Streptococcus pneumoniae마크로라이드는 마크로라이드 내성 폐렴구균의 친염증 활성을 감소시킨다.Article Published on 2023-05-162024-07-28 Journal: Microbiology Spectrum [Category] 폐렴구균 감염증, [키워드] Inflammation Lipoproteins Lipoteichoic acid Macrolide-resistant macrolides peptidoglycan [DOI] 10.1128/spectrum.00148-23 PMC 바로가기
Is there any association between plasma lipid profile and severity of COVID-19?혈장 지질 프로필과 COVID-19의 중증도 사이에 연관성이 있습니까?Article Published on 2022-06-012022-09-11 Journal: Clinical nutrition ESPEN [Category] COVID19(2023년), SARS, 변종, 치료제, [키워드] analyzed association atorvastatin Care caused characterized cholesterol concerning coronavirus correlated COVID-19 COVID-19 patient COVID-19 patients disease Disease progression disease severity event HDL-C HDL-cholesterol ICU Infectious disease Intensive LDL-C LDL-cholesterol less Lipoproteins majority multivariate multivariate Cox regression analysis non-survivor Non-survivors pandemic parameter Patient plasma plasma lipoprotein plasma lipoproteins Prognosis question regression analysis respiratory symptoms SARS-CoV-2 severity severity of COVID-19 single-center study statins survivor the patient Total cholesterol variant with COVID-19 [DOI] 10.1016/j.clnesp.2022.04.026 PMC 바로가기 [Article Type] Article
Metabolic and Lipidomic Markers Differentiate COVID-19 From Non-Hospitalized and Other Intensive Care PatientsMolecular Biosciences Published on 2021-12-022022-10-31 Journal: Frontiers in Molecular Biosciences [Category] COVID-19, [키워드] acute COVID-19 acute respiratory syndrome affecting age Analysis analyzed anti-SARS-CoV-2 atherosclerotic caused change cholesterol collected coronavirus Coronavirus disease 2019 correlated Course COVID-19 COVID-19 patient COVID-19 patients demonstrated glycine healthy control healthy controls high-density highlighting individual individuals intensive care intensive care patients lipid metabolism lipoprotein cholesterol Lipoproteins metabolic metabolic parameters metabolic processes metabolomics NMR nuclear organ system Other Particle Patient profile question risk factor SARS-CoV-2 serum serum sample Shock significantly significantly increased Stratification the disease viral infection [DOI] 10.3389/fmolb.2021.737039 PMC 바로가기 [Article Type] Molecular Biosciences
SARS-CoV-2 infection as a trigger of humoral response against apolipoprotein A-1SARS-CoV-2 감염은 Apolipoprotein A-1에 대한 체액 반응을 유발합니다.Article Published on 2021-11-012022-09-12 Journal: European Journal of Clinical Investigation [Category] MERS, SARS, 진단, [키워드] anti-apolipoprotein A-1 autoantibodies anti-SARS-CoV-2 anti-SARS-CoV-2 IgG association Autoimmune Autoimmunity bioinformatics Case-control clinical settings Cohort COVID-19 COVID-19 pandemic COVID-19 patient COVID-19 prognosis cross-reactivity cytokine epitope Epitopes experiment experimental evidence General population healthy donor high-density homology humoral ICU Patients IgG IgG level immunoassay individual induce intensive care linear Lipoproteins molecular molecular mimicry peptide Prognosis prognostic Protein receptor SARS-CoV-2 SARS-COV-2 infection scrutiny sequence sequence homology seroconversion rate seronegative seropositive individual Significant spike Spike protein target the disease therapeutic TLR2 Toll-like receptor toll-like receptor 2. triggered were assessed were used [DOI] 10.1111/eci.13661 PMC 바로가기 [Article Type] Article
Hypomorphic ASGR1 modulates lipid homeostasis via INSIG1-mediated SREBP signaling suppressionResearch Article Published on 2021-10-082023-08-30 Journal: JCI Insight [Category] E형 간염, [키워드] Atherosclerosis cholesterol Lipoproteins metabolism [DOI] 10.1172/jci.insight.147038 PMC 바로가기 [Article Type] Research Article
The Role of High-Density Lipoprotein in COVID-19Pharmacology Published on 2021-07-162022-10-31 Journal: Frontiers in Pharmacology [Category] COVID-19, [키워드] abnormal coagulation acutely ill patient Analysis angiotensin-converting enzyme 2 anti-apoptotic antioxidant binding change Characteristics cholesterol clinical complications Coronavirus disease 2019 correlated COVID-19 death disease severity dysregulated immune response Effects Evidence Fatality rate functions HDL high-density Inflammatory response lipoprotein Lipoproteins LPS managing mechanism Mortality multiple-organ failure neutralize pandemic pathogenesis of COVID-19 pathophysiological pathophysiological feature Patient patients with COVID-19 pleiotropic reducing Regulation role SARS-CoV-2 severe COVID-19 significantly therapy Transport unique [DOI] 10.3389/fphar.2021.720283 PMC 바로가기 [Article Type] Pharmacology