The effect of renal impairment and obesity on anti-Xa peak and trough levels in patients receiving therapeutic doses of nadroparin: a comparison with control patientsarticle Published on 2023-09-142024-09-05 Journal: European Journal of Clinical Pharmacology [Category] update2024, [키워드] anti-Xa dose reduction LMWH Nadroparin obesity renal impairment [DOI] 10.1007/s00228-023-03558-5 PMC 바로가기 [Article Type] article
Thromboprophylaxis with standard- vs. flexible-dose heparin for hospitalized COVID-19 patients: a target trial emulationResearch article Published on 2022-11-012022-10-05 Journal: Journal of clinical epidemiology [Category] 임상, [키워드] 28-day mortality 95% confidence interval Anticoagulants anticoagulation baseline bleeding Coagulopathy COVID-19 COVID-19 diagnosis COVID-19 drug treatment dose eligible Epidemiological methods estimate hazard ratio hospitalized COVID-19 hospitalized COVID-19 patient hospitalized COVID-19 patients intensity intermediate dose laboratory abnormality LMWH Low–molecular weight heparin Major Mortality objective Observational data Patient Result risk setting Spain Standard dose survival target Target trial emulation Thromboprophylaxis thrombosis thrombotic risk Trial [DOI] 10.1016/j.jclinepi.2022.08.006 [Article Type] Research article
Thrombotic and bleeding complications in patients with chronic lymphocytic leukemia and severe COVID-19: a study of ERIC, the European Research Initiative on CLLArticle Published on 2022-08-262022-11-15 Journal: Journal of Hematology & Oncology [Category] SARS, 진단, [키워드] 95%CI Admission advanced age affected age albumin Analysis anticoagulation therapy bleeding C-reactive protein CLL Complication conducted COVID-19 COVID-19 diagnosis D-dimer Data collection death deficiency defined development dose administration ENhance European event high risk Hospitalization Hospitalized ICU immune increased risk initiative leukemia LMWH Most patient multivariate model nasal Occurrence outcomes oxygen oxygen supplementation Patient peak D-dimer pharyngeal polymerase chain presence of comorbidities Prognostic factor prophylactic dose Protective receiving recommendation reported Retrospective multicenter study risk RT-PCR SARS-CoV-2 severe COVID-19 severity STROBE susceptible swabs the disease Thromboembolic event Thromboprophylaxis thrombosis Thrombotic events Treatment treatment for COVID-19 were used [DOI] 10.1186/s13045-022-01333-0 PMC 바로가기
Thromboembolic events in COVID-19 ambulatory patients: An observational study about incidence, and thromboprophylaxis outcomesObservational Study Published on 2022-08-042022-10-05 Journal: PLoS ONE [Category] 임상, [키워드] age ambulatory patients Cohort Complication complications conducted COVID-19 defined described eight event FIVE Hemorrhagic hemorrhagic event high risk incidence LMWH management occurred outcome Patient prophylactic strategy rivaroxaban thromboembolic complication Thromboprophylaxis venous venous thromboembolic [DOI] 10.1371/journal.pone.0270195 PMC 바로가기 [Article Type] Observational Study
2022 international clinical practice guidelines for the treatment and prophylaxis of venous thromboembolism in patients with cancer, including patients with COVID-19Review article Published on 2022-06-272022-10-05 Journal: The Lancet. Oncology [Category] 임상, 치료법, [키워드] absence ambulatory patient anticancer bleeding Clinical practice Consensus drug–drug interaction Guidance heparin high risk include independent initial initiative International literature review LMWH oral anticoagulant Pancreatic cancer Patient Patients with cancer patients with COVID-19 postoperative Prevent Prophylaxis recommendation risk therapy thrombosis treat treated Treatment Venous Thromboembolism with COVID-19 [DOI] 10.1016/S1470-2045(22)00160-7 [Article Type] Review article
Clinical features and major bleeding predictors for 161 fatal cases of COVID-19: A retrospective observational studyObservational Study Published on 2022-04-012022-10-05 Journal: Bosnian Journal of Basic Medical Sciences [Category] 임상, [키워드] Acute kidney injury age ARDS C-reactive protein change Characteristics clinical collected Complication complications correlation COVID-19 CRP D-dimer Diabetes Mellitus died Disseminated intravascular coagulation events feature hemoglobin hemoptysis Hospitalization hypertension In-hospital in-hospital complication in-hospital complications independent predictor INR intensive care International Laboratory laboratory parameter liver LMWH low molecular weight major bleeding male median age myocardial injury non-survivor normalized parameter Patient patients with COVID-19 Platelet predictor proportion regression analysis retrospective Retrospective study risk factor suffered the patient were recorded with COVID-19 [DOI] 10.17305/bjbms.2021.6577 PMC 바로가기 [Article Type] Observational Study
How the Innate Immune System of the Blood Contributes to Systemic Pathology in COVID-19-Induced ARDS and Provides Potential Targets for Treatment혈액의 타고난 면역 체계가 COVID-19 유발 ARDS의 전신 병리에 기여하고 치료를 위한 잠재적인 표적을 제공하는 방법Review Published on 2022-03-082022-09-11 Journal: Frontiers in Immunology [Category] MERS, SARS, 유전자 메커니즘, 진단, [키워드] Activation Acute kidney injury acute respiratory distress acute respiratory distress syndrome AMY-101 Angiogenesis apoptotic cells ARDS Biomarker bradykinin candidate drug candidate drugs cascade cascade system characterized chemokines Coagulation Coagulation system complement Complement inhibitor complement inhibitors Compound COVID-19 Crosstalk cytokine Cytokines damaged demonstrated dysregulation ecallantide eculizumab Evidence favor ground glass opacities heparin High dose high risk Icatibant IL-6 IL-6 levels in some incidence include Influenza influenza-like symptom Influenza-like symptoms inhibitor initiated Innate innate immune system intensive care treatment Kallikrein lanadelumab lead leukocytes life-threatening LMWH Lung injury mechanical ventilation mechanism moderate MOST oxygen oxygen saturation pandemic pathophysiology Patient patients Phase I plasma plasma proteins Platelets Potential predict Prevent Prognostic value pulmonary damage pulmonary inflammation receptor reduced Regulation respiratory distress Respiratory distress syndrome SARS-CoV-2 SARS-CoV-2 infected patient severity Support survival syndrome System systemic target the disease therapeutic option therapeutic options Thromboembolism thrombosis thrombotic Thrombotic complications translated Treatment treatment of COVID-19 Trial Usage Vascular ventilator virus [DOI] 10.3389/fimmu.2022.840137 PMC 바로가기 [Article Type] Review
Splenic infarct in a COVID-19 patient under anticoagulant therapy with normal D-dimer levelsCase report Published on 2022-03-012022-10-05 Journal: International Journal of Surgery Case Reports [Category] 유전자 메커니즘, 치료제, [키워드] abdominal pain Acute myocardial infarction Anticoagulant anticoagulant therapy Anticoagulant treatment chest pain Coagulopathy Computerized tomography COVID-19 COVID-19 patient D-dimer level described discharged drug dose ECG Follow-up Hospitalization hospitalized COVID-19 patient laboratory parameter Leukocytosis LMWH multisystemic Myocardial nine Patient patients PCR positivity Pneumonia presenting Prevent problem prophylactic dose Prophylaxis receiving Seven shown Splenic Splenic infarction Thromboembolism thrombosis Thrombotic events Treatment was increased was performed [DOI] 10.1016/j.ijscr.2022.106847 [Article Type] Case report
Spontaneous Hematomas and Deep Vein Thrombosis during the Recovery from a SARS-CoV-2 Infection: Case Report and Literature ReviewReview Published on 2022-02-022022-10-30 Journal: Medicina [Category] COVID-19, COVID19(2023년), MERS, SARS, [키워드] Acute kidney injury acute respiratory syndrome Anemia Clinical practice COVID-19 COVID-19 infection deep Deep vein thrombosis described DVT hematoma Hemorrhagic hemorrhagic events heparin Infection less literature LMWH low molecular weight Low molecular weight heparins Mild moderate Occurrence Patient popliteal report review SARS-CoV-2 Spontaneous spontaneous hematoma Spread strain suffered the patient Thromboembolic event thrombosis treated Vein virus [DOI] 10.3390/medicina58020230 PMC 바로가기 [Article Type] Review
The Association of Low Molecular Weight Heparin Use and In-hospital Mortality Among Patients Hospitalized with COVID-19Observational Study Published on 2022-02-012022-10-05 Journal: Cardiovascular Drugs and Therapy [Category] 임상, [키워드] 95% CI adjusted adjusted odds ratio age Analysis association benefit CHD conducted Coronary heart disease COVID-19 Critically ill D-dimer demonstrated determine diabetes Elderly patient enrolled had more heparin hospital hospitalized COVID-19 patients hypertension IL-6 in-hospital mortality in-hospital mortality rate Inflammatory cytokine IQR limit LMWH LMWH. low molecular weight median age men Mortality mortality risk Older parameter Patient patients with COVID-19 Primary outcome Retrospective study severe COVID-19 severely ill patients survival treated weight with COVID-19 Wuhan, China [DOI] 10.1007/s10557-020-07133-3 PMC 바로가기 [Article Type] Observational Study