Challenges in LncRNA Biology: Views and OpinionsViewpoint Published on 2024-08-012024-09-05 Journal: Non-Coding RNA [Category] update2024, [키워드] Cancer COVID-19 deep learning Large language models lncRNA datasets lncRNAs [DOI] 10.3390/ncrna10040043 PMC 바로가기 [Article Type] Viewpoint
Comprehensive characterization of stemness-related lncRNAs in triple-negative breast cancer identified a novel prognostic signature related to treatment outcomes, immune landscape analysis and therapeutic guidance: a silico analysis with in vivo experimentsResearch Published on 2024-05-042024-09-05 Journal: Journal of Translational Medicine [Category] update2024, [키워드] Cancer stem cells immune microenvironment lncRNAs personalized treatment prognostic model triple-negative breast cancer [DOI] 10.1186/s12967-024-05237-0 PMC 바로가기 [Article Type] Research
Exploring the Therapeutic Significance of microRNAs and lncRNAs in Kidney DiseasesReview Published on 2024-01-192024-09-05 Journal: Genes [Category] update2024, [키워드] Gene regulation Kidney diseases lncRNAs MicroRNAs nephropathy therapy [DOI] 10.3390/genes15010123 PMC 바로가기 [Article Type] Review
The role of long noncoding RNAs in malaria parasitesarticle Published on 2023-07-312024-09-01 Journal: Trends in Parasitology [Category] 말라리아, [키워드] Chromatin structure epigenetics Gene regulation lncRNAs malaria Plasmodium [Article Type] article
microRNAs and Inflammatory Immune Response in SARS-CoV-2 Infection: A Narrative ReviewReview Published on 2022-02-152022-10-29 Journal: International Review of Cell and Molecular Biology [Category] COVID-19, [키워드] “cytokine storm” Asymptomatic Biomarker chemokines clinical manifestation complications Course COVID-19 COVID-19 infection Cytokine storm diagnostic Diseases driven by excessive immune response host miRNA immune response induce Inflammatory inflammatory pathway Inflammatory response International life-threatening lncRNAs microRNA mild case miRNAs narrative ncRNA ncRNAs non-coding RNA Proinflammatory cytokine question Research response review SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 miRNA SARS-CoV-2 pandemic therapeutic thought Topic [DOI] 10.3390/life12020288 PMC 바로가기 [Article Type] Review
Macrophage Activation Syndrome and COVID 19: Impact of MAPK Driven Immune-Epigenetic Programming by SARS-Cov-2Immunology Published on 2021-10-012022-11-01 Journal: Frontiers in Immunology [Category] COVID-19, MERS, SARS, [키워드] COVID COVID-19 immune polarization Impact Inflammasome lncRNAs Macrophage MAPK miRNA TLRs (toll-like receptors) [DOI] 10.3389/fimmu.2021.763313 PMC 바로가기 [Article Type] Immunology
SARS-CoV-2 transgressing LncRNAs uncovers the known unknownsLncRNA를 횡단하는 SARS-CoV-2는 알려진 미지의 것을 밝힙니다.Editorial Published on 2021-10-012022-09-11 Journal: Physiological Genomics [Category] SARS, 유전자 메커니즘, [키워드] asked disease pathogenesis endocytosis functional Functional genomics Host host pathogenesis hypothetical lncRNA lncRNAs long noncoding RNA mechanism molecules Open reading frame ORFs Pathogenesis Pathways Perspective Region regulate Regulatory SARS-CoV-2 SARS-CoV-2 pathogenesis the disease transgression. viral infection viral pathogenesis Viral protein Viral proteins [DOI] 10.1152/physiolgenomics.00075.2021 PMC 바로가기 [Article Type] Editorial
Long Noncoding RNAs as Emerging Regulators of COVID-19COVID-19의 새로운 조절자로서의 긴 비코딩 RNAReview Published on 2021-08-022022-09-11 Journal: Frontiers in Immunology [Category] MERS, SARS, 바이오마커, 유전자 메커니즘, 치료제, [키워드] (Tocilizumab) acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus-2 Antiviral antiviral immune response antiviral immune responses antiviral role biological processe biological processes cellular changes in Clinical treatment coronavirus disease Coronavirus disease 2019 Coronavirus-2 COVID-19 COVID-19 treatment death Dexamethasone disease drug Evidence expression glucocorticoid Glucocorticoids help Host host transcriptome immune dysfunction Immune escape immune responses incidence rate indicate Infection Inflammatory response inhibiting interferons involved lncRNA lncRNAs Long long noncoding RNA mechanisms monoclonal antibodies monoclonal antibody Occurrence pandemic pathology regulate Regulation regulator Research respiratory resulting RNA SARS-CoV-2 SARS-COV-2 infection Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus-2 Spread subsequent therapeutic thrombosis Tocilizumab Transcriptome Treatment type I interferon type I interferons up-regulate Viral viral gene viral genes viral infections viral replication virus infection virus infections [DOI] 10.3389/fimmu.2021.700184 PMC 바로가기 [Article Type] Review
Coronavirus Disease (COVID)-19 and Diabetic Kidney DiseaseReview Published on 2021-07-302022-10-28 Journal: Pharmaceuticals [Category] COVID-19, [키워드] accelerate ACE2 Activation acute respiratory syndrome addition Altered AMP-activated protein kinase (AMPK) AMPK angiotensin-converting enzyme (ACE) angiotensin-converting enzyme 2 Cell cell type cell types cells cellular homeostasis circular RNAs coronavirus Coronavirus Disease (COVID)-19 COVID-19 associated nephropathy COVID-19 patients COVID-19 severity Cytokine storm diabete diabetes Diabetic diabetic kidney disease dipeptidyl peptidase (DPP)-4 disrupt endothelial cells endothelial-to-mesenchymal transition endotheliopathy epithelial cells epithelial-to-mesenchymal transition expression facilitate fibrosis homeostasis Infection Injury interact kidney Kidney disease Kidney diseases lncRNAs Macrophage macrophages MAS1 mechanism microRNA MicroRNAs Neutrophils organ Organ failure pathogenic Platelets protective role Protein Proteins provided reaction receptor Replication resulting SARS-CoV-2 severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Signaling stability standard care Support target therapy thrombus formation viral entry [DOI] 10.3390/ph14080751 PMC 바로가기 [Article Type] Review
Identification and characterization of lncRNA AP000253 in occult hepatitis B virus infectionResearch Published on 2021-06-102023-06-02 Journal: Virology Journal [Category] B형 간염, [키워드] AP000253 Biomarker Hepatitis B virus lncRNAs Occult infection [DOI] 10.1186/s12985-021-01596-y PMC 바로가기 [Article Type] Research