ChAdOx1 nCoV-19 (AZD1222) protects Syrian hamsters against SARS-CoV-2 B.1.351 and B.1.1.7ChAdOx1 nCoV-19(AZD1222)는 SARS-CoV-2 B.1.351 및 B.1.1.7로부터 시리아 햄스터를 보호합니다.Article Published on 2021-10-072022-09-10 Journal: Nature Communications [Category] MERS, SARS, 변종, 진단, 치료기술, [키워드] animals Antibody titer AZD1222 B.1.1.7 B.1.1.7 variants B.1.351 caused ChAdOx1 ChAdOx1 nCoV-19 ChAdOx1 nCoV-19 vaccine clinical disease disease Effectiveness Efficacy hamster hamsters infection with SARS-CoV-2 Infectious virus investigated lesions Live attenuated vaccines lose weight lung Lungs Neutralizing antibody titer observé Pathogens Pneumonia PROTECT Pulmonary infection Pulmonary pathology raise reduction Replication RNA SARS-CoV-2 SARS-CoV-2 disease SARS-CoV-2 variant SARS-CoV-2 variants sera sgRNA single dose These data Vaccine Vaccines Viral virus VOCs weight [DOI] 10.1038/s41467-021-26178-y PMC 바로가기 [Article Type] Article
Hamsters as a Model of Severe Acute Respiratory Syndrome Coronavirus-2중증 급성 호흡기 증후군 코로나바이러스-2의 모델로서의 햄스터Review Published on 2021-10-012022-09-11 Journal: Comparative medicine [Category] MERS, SARS, 변종, 진단, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus Affect age alveolar animal model animal models clinical disease Clinical outcome clinical outcomes Clinical sign Clinical signs contributed convalescent serum coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 Critical death develop edema Effect Efficacy granulocyte hamster hamsters Health hemorrhage highlight human infection human infections humans Implications infected with SARS-CoV-2 Infection infiltration Injury inoculation interstitial lead lethargy lose weight Mesocricetus Model Mortality pandemic Pathogenesis Pneumonia preclinical studies preclinical study progression of disease pulmonary lesion pulmonary lesions Pulmonary pathology renal required respiratory Respiratory disease Respiratory system ruffled fur SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 infections severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 Severe infection severe infections Sex shown Spread Therapeutics Treatment vaccination virus variant virus variants weight while [DOI] 10.30802/AALAS-CM-21-000036 PMC 바로가기 [Article Type] Review
Changes in sleep phase and body weight of mobile health App users during COVID-19 mild lockdown in Japan일본 코로나19 경미한 락다운 기간 동안 모바일 건강 앱 사용자의 수면 단계 및 체중 변화Brief Communication Published on 2021-07-032022-09-12 Journal: International journal of obesity (2005) [Category] MERS, 진단, [키워드] association average benefit body weight change changes characteristic Chronotype confounding factor confounding factors COVID-19 COVID-19 pandemic cross-sectional cross-sectional study cumulative decrease delayed sleep phase described diet Epidemiology Evidence investigated Japan knowledge large cohort large sample lockdown lose weight management Mild Mobile health obesity objective offset participant physical activity reported Result Risk factors Sleep Study design weight weight decrease weight gain Weight management [DOI] 10.1038/s41366-021-00890-7 PMC 바로가기 [Article Type] Brief Communication
Prior aerosol infection with lineage A SARS-CoV-2 variant protects hamsters from disease, but not reinfection with B.1.351 SARS-CoV-2 variant혈통 A SARS-CoV-2 변이체를 사용한 이전 에어로졸 감염은 햄스터를 질병으로부터 보호하지만 B.1.351 SARS-CoV-2 변이체에 의한 재감염은 보호하지 않습니다.Research Article Published on 2021-06-262022-09-10 Journal: Emerging Microbes & Infections [Category] SARS, 변종, 진단, [키워드] aerosol aerosol exposure anamnestic response B.1.351 caused circulation Contact direct contact disease exposure to fomite hamster hamsters HCoV HCoV-19 Heterologous humoral induce Infection Infection route infection with SARS-CoV-2 Infectious virus initial intranasal Lineage lose weight low dose Lungs majority mild infection naïve neutralization neutralize Neutralizing onward transmission pathology Prevent PROTECT protective immunity provide Pulmonary pathology Reinfection remained Replication SARS-CoV-2 SARS-CoV-2 variant seroconverted Syrian hamster These data titre titres Transmission triggered variants variants of concern virus VoC VOCs WA1 weight weight loss [DOI] 10.1080/22221751.2021.1943539 PMC 바로가기 [Article Type] Research Article