Prediction of intravenous immunoglobulin retreatment in children with Kawasaki disease using models combining lymphocyte subset and cytokine profile in an East Asian cohortOriginal Article Published on 2024-03-132024-09-05 Journal: Clinical & Translational Immunology [Category] update2024, [키워드] Cytokines Inflammation IVIG retreatment Kawasaki disease Lymphocyte subset [DOI] 10.1002/cti2.1498 PMC 바로가기 [Article Type] Original Article
Adaptive immune dysfunction in patients with COVID-19 and impaired kidney function during the omicron surgeArticle Published on 2023-02-182024-09-05 Journal: Clinical immunology (Orlando, Fla.) [Category] update2024, [키워드] COVID-19 Impaired kidney function Lymphocyte subset omicron outcomes [DOI] 10.1016/j.clim.2023.109271 PMC 바로가기 [Article Type] Article
AYURAKSHA, a prophylactic Ayurvedic immunity boosting kit reducing positivity percentage of IgG COVID-19 among frontline Indian Delhi police personnel: A non-randomized controlled intervention trialClinical Trial Published on 2022-08-162022-10-04 Journal: Frontiers in Public Health [Category] SARS, 임상, 진단, [키워드] Analysis Anu AYURAKSHA kit Ayurveda Blood blood sugar C-reactive protein CD3 CD4 CD8 clinical control group controls COVID-19 COVID-19 crisis COVID-19 infection COVID-19 pandemic determine distribution dysregulated effective Efficacy effort erythrocyte sedimentation rate evaluated hematological hematological parameter hematological parameters IgG IgG positivity IL-6 IL-6 level Immunity incidence India Infection inflammation marker Intervention life lower risk Lymphocyte subset management Medicine Mortality no increase non-randomized pandemic participant Participants post-intervention Primary outcome Prophylactic Quality Quality of life Quality of life (QoL) random reduced reducing Research secondary outcome severity of COVID-19 significantly significantly lower status the WHO Trial Version [DOI] 10.3389/fpubh.2022.920126 PMC 바로가기 [Article Type] Clinical Trial
Immune Cells Profiles In The Peripheral Blood Of Patients With Moderate To Severe COVID-19 And Healthy Subjects With and Without Vaccination With The Pfizer-BioNTech mRNA VaccinePfizer-BioNTech mRNA 백신 접종 여부에 관계없이 중등도에서 중증 COVID-19 환자 및 건강한 피험자의 말초혈 면역 세포 프로필Article Published on 2022-07-112022-09-11 Journal: Frontiers in Immunology [Category] COVID19(2023년), SARS, 치료기술, [키워드] acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 adaptive analyzed B cell B cells Blood causative agent caused CD14 CD16 CD19 CD19+ CD3+ CD4+ CD4+ T cells CD4+ T lymphocyte CD56 CD56+ CD8+ T cell CD8+ T cells clinical manifestations coronavirus 2 coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patient COVID-19 patients detectable determine dysregulated flow cytometry Frequency group healthy control healthy subject healthy subjects HLA-DR host response immune Immune cell immune cells immune response Inflammatory Kuwait lymphocyte Lymphocyte subset Lymphocyte subsets Lymphocytes moderate moderate to severe monocyte monocyte subsets Monocytes mRNA mRNA vaccine NK cell NK cells no symptom no symptoms percentage percentages peripheral Peripheral blood Perturbation perturbations Pfizer Pfizer-BioNTech profile profiles PROTECT required respiratory SARS-CoV-2 Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus severe disease significantly higher significantly lower subjects subset T cells T lymphocytes the patient three group three groups vaccination was performed with COVID-19 [DOI] 10.3389/fimmu.2022.851765 PMC 바로가기 [Article Type] Article
Peripheral lymphocyte subset counts predict antibody response after SARS-CoV-2 mRNA-BNT162b2 vaccine in cancer patients: Results from the Vax-On-Profile study말초 림프구 하위 집합 수는 암 환자에서 SARS-CoV-2 mRNA-BNT162b2 백신 후 항체 반응을 예측합니다: Vax-On-Profile 연구 결과Article Published on 2022-07-012022-09-11 Journal: International immunopharmacology [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술, [키워드] Adaptive immune response Analysis anti-RBD Antibody Response Antibody titer Antibody titers B cell B cells Cancer cancer patient Cancer patients Chemotherapy circulating collected correlation Corticosteroid corticosteroid therapy COVID-19 COVID-19 vaccination Cytotoxic chemotherapy defined Flow cytometry analysis helper cell humoral humoral immunogenicity Humoral response IgG IgG antibodies IgG antibody IgG titer immunosuppressive indicated interactions linear correlation lymphocyte Lymphocyte subset Lymphocyte subsets mRNA Multivariate analysis Negative predictive value Occurrence Patient peripheral Peripheral blood positive positive linear correlation predict Predictive Predictive value Protein Quantitative RBD receiving Receptor-binding domain Result ROC Curve SARS-CoV-2 SARS-CoV-2 spike protein SARS-CoV-2 vaccine seroconversion rate seroconversion rates seroconversion response serologic testing Serologically shown significantly spike Spike protein subgroups subpopulations subset symptomatic infections T helper T helper cell T helper cell. tested the receptor-binding domain the SARS-CoV-2 treated Univariate analysis vaccination efficacy Vaccine [DOI] 10.1016/j.intimp.2022.108774 PMC 바로가기 [Article Type] Article
Contribution of CD4+ T cell-mediated inflammation to diarrhea in patients with COVID-19COVID-19 환자의 설사에 대한 CD4+ T 세포 매개 염증의 기여Article Published on 2022-07-012022-09-11 Journal: International Journal of Infectious Diseases [Category] Coronavirus, COVID19(2023년), SARS, 바이오마커, 유전자 메커니즘, 치료기술, [키워드] ACE2 analyzed angiotensin Angiotensin-converting enzyme angiotensin-converting enzyme 2 association CD4/CD8 CD4+ CD4+ T cell CD4+ T cells Cell cells chemokine chemokines Colon contribute correlation analyses Correlation analysis COVID-19 CXCL10 CXCL11 CXCR3 determine diarrhea distribution expressed expression groups Gut identify Inflammation inflammation sites lymphocyte Lymphocyte subset Lymphocyte subsets mechanism Migration mRNA mRNA expression Necrosis no difference Patient patients with COVID-19 percentage percentages performed protease protein levels receptor SARS-CoV-2 SARS-COV-2 infection Serine serine 2 significant difference T cell T cells T-box TNFα transmembrane transmembrane protease serine 2 Tumor tumor necrosis tumor necrosis factor tumor necrosis factor-alpha [DOI] 10.1016/j.ijid.2022.04.006 PMC 바로가기 [Article Type] Article
Characteristics of lymphocyte subsets and cytokine profiles of patients with COVID-19COVID-19 환자의 림프구 하위 집합 및 사이토카인 프로필의 특성Article Published on 2022-03-282022-09-11 Journal: Virology Journal [Category] 변종, 치료기술, [키워드] Abnormalities age Analysis analyzed AUC B cells Care CD19 CD3 CD4 CD8 Cell Chongqing clinical Clinical and laboratory data coronavirus disease COVID-19 COVID-19 patient COVID-19 patients Critical cutoff value cytokine cytokine profile Cytokines diabetes Diabetes Mellitus enrolled evaluate Factor Hospital admission ICU ICU admission ICU patient ICU Patients IL-6 independent predictor independent predictors Infection interleukin laboratory data Logistic regression Logistic regression analysis lymphocyte Lymphocyte subset Lymphocyte subsets Lymphocytes lymphopenia Most patients multivariate multivariate logistic regression analysis mutant natural killer no statistical difference No statistical differences non-ICU non-ICU patient non-ICU patients Odds ratio Patient patients patients with COVID-19 peripheral lymphocyte Predictive Predictive value receiver operating characteristic ROC ROC Curve selected sensitivity severe disease severe group severity severity of COVID-19 significantly significantly higher specificity statistical differences subset T cell T cells tested the disease Three Gorge Three Gorges treated university virus infection was used wild-type virus [DOI] 10.1186/s12985-022-01786-2 PMC 바로가기 [Article Type] Article
Peripheral lymphocyte subset alteration in patients with COVID-19 having differential clinical manifestationsArticle Published on 2022-01-012023-08-30 Journal: The Indian journal of medical research [Category] E형 간염, [키워드] Asymptomatic Lymphocyte subset mild symptomatic moderate +severe patients recovered individuals. SARS-CoV-2 [DOI] 10.4103/ijmr.IJMR_453_21 PMC 바로가기
T cell counts and IL-6 concentration in blood of North African COVID-19 patients are two independent prognostic factors for severe disease and death북아프리카 COVID-19 환자의 혈액 내 T 세포 수와 IL-6 농도는 심각한 질병 및 사망에 대한 두 가지 독립적인 예후 인자입니다Article Published on 2022-01-012022-09-11 Journal: Journal of leukocyte biology [Category] 바이오마커, [키워드] 95% confidence interval acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 addition African Analysis B cells Blood CD4+ T cells CD8+ T cell CD8+ T cells characteristic clinician Concentration coronavirus coronavirus disease Coronavirus disease 2019 correlated COVID-19 COVID-19 patient COVID-19 patients cutoff value cytokine cytokine level cytokine levels Cytokines death death group develop disease flow cytometry healthy control healthy controls help high risk IL-10 IL-6 immune parameter immune system independent investigated lymphocyte Lymphocyte subset Lymphocyte subsets Lymphocytes Mild Mortality multivariate logistic regression multivariate logistic regression analysis natural killer cell Natural killer cells North outcome parameter pathology Patient patients percentage percentages performed Peripheral blood peripheral blood lymphocyte predict Prognosis Prognostic factor receiver operating characteristic respiratory risk ROC ROC curves SARS-CoV2 severe acute respiratory syndrome Coronavirus severe cases severe disease severity severity of illness significant difference significant differences significantly higher statistical difference statistical differences subset survival T cell T cells Th17 Th2 the disease the patient threshold Total two group two groups [DOI] 10.1002/JLB.4COVA1020-703R PMC 바로가기 [Article Type] Article
COVID-19 and Cancer: Discovery of Difference in Clinical Immune IndexesResearch Article Published on 2021-10-182022-10-29 Journal: Journal of Immunology Research [Category] COVID-19, MERS, SARS, [키워드] Acute inflammation affected analyzed ANOVA B cell B cells Cancer Cancer patients cancers carried CD16 CD19 CD3 CD4 CD56 CD8 changes in characteristic chi-square test clinical correlation Correlation analysis COVID-19 COVID-19 patient COVID-19 patients cytokine Cytokines diagnostic difference Diseases Effect identify IFN IL-10 IL-2 IL-4 IL-6 Immune cell immune disorder involved Lymphocyte subset lymphopenia Monocytes Neutrophils NK cell no significant difference objective outcomes parameter Patient patients with COVID-19 Result Retrospective study ROC severe COVID-19 patient significant difference Stage subgroup analysis subset T cell T cells TNF- α two subgroups variable were measured with COVID-19 [DOI] 10.1155/2021/8669098 PMC 바로가기 [Article Type] Research Article