IFNL4, ACE1, PKR, IFNG, MBL2 genetic polymorphisms and severe COVID-19: A protocol for systematic review and meta-analysisIFNL4, ACE1, PKR, IFNG, MBL2 유전적 다형성 및 중증 COVID-19: 체계적인 검토 및 메타 분석을 위한 프로토콜Article Published on 2022-05-272022-09-11 Journal: Medicine [Category] COVID19(2023년), MERS, meta-analysis, SARS, [키워드] ACE-2 ACE1 angiotensin angiotensin-2 converting enzyme association caused Chinese Cochrane Handbook Cochrane Library Corona virus COVID-19 disease Effect English enzyme evaluated Evidence Genetic polymorphism genetic polymorphisms Google Scholar Handbook host cells IFNg IFNL4 include MBL2 Meta-analysis Methodological quality pathogenic peer-reviewed PKR Population progression PROSPERO protocol registration number researcher review SARS-CoV-2 severe COVID-19 submitted systematic review systematic reviews Virus Disease Web of Science [DOI] 10.1097/MD.0000000000029405 PMC 바로가기 [Article Type] Article
Investigation of MBL2 and NOS3 functional gene variants in suspected COVID-19 PCR (-) patientsCOVID-19 PCR 의심 환자에서 MBL2 및 NOS3 기능 유전자 변이체 조사Article Published on 2022-05-012022-09-11 Journal: Pathogens and global health [Category] 변종, [키워드] absence allele can be used coronavirus disease coronavirus disease-2019 COVID-19 COVID-19 patient CT diagnosed with COVID-19 Early detection endothelial Endothelial nitric oxide synthase (eNOS) Factor functional gene Genotype healthy control healthy controls Infection initial investigation Isolation lung involvement mannose mannose-binding lectin 2 (MBL2). MBL2 nasopharyngeal nitric oxide nitric oxide synthase NOS3 Patient PCR PCR-negative PCR-positive performed polymorphism Research risk significantly higher statistical analysis university hospital variant viral loads [DOI] 10.1080/20477724.2021.1984726 PMC 바로가기 [Article Type] Article
Functional Single-Nucleotide Polymorphisms in the MBL2 and TLR3 Genes Influence Disease Severity in Influenza A (H1N1)pdm09 Virus-Infected Patients from Maharashtra, IndiaArticle Published on 2022-05-012023-06-23 Journal: Viral immunology [Category] 신종인플루엔자, [키워드] Gene polymorphisms IFITM3 influenza A (H1N1)pdm09 virus. MBL2 TLR3 TNFA [DOI] 10.1089/vim.2021.0179
Recognition and inhibition of SARS-CoV-2 by humoral innate immunity pattern recognition molecules Research Published on 2022-01-312022-10-05 Journal: Nature Immunology [Category] COVID19(2023년), SARS, 바이오마커, 변종, 유전자 메커니즘, [키워드] activated Activation acute respiratory syndrome binding Biomarker complement coronavirus coronavirus disease COVID-19 disease severity functions glycosylation site humoral Implications in vitro include inhibited Innate immunity Interaction lectin pathway locus MBL2 omicron Pathogenesis polymorphism predicted Ptx3 Recognition recognize SARS-CoV-2 selected Spike protein Spike proteins tested the viral nucleocapsid translational Trimeric spike protein variants of concern [DOI] 10.1038/s41590-021-01114-w [Article Type] Research
Potential Genes Associated with COVID-19 and ComorbidityCOVID-19 및 동반이환과 관련된 잠재적 유전자Research Paper Published on 2022-01-242022-09-10 Journal: International Journal of Medical Sciences [Category] 변종, [키워드] ACE AGT Analysis bioinformatics candidate gene CCR5 Comorbidities Comorbidity contribute Coronary artery Coronary artery disease coronavirus coronavirus disease COVID-19 CX3CR1 cytokine cytokine inhibitors cytokine receptor diabetes Diabetes Mellitus disease severity drug and vaccine development Efficacy enrichment analyses evaluated explain Factor Fenofibrate Genetic genetic factors GO term help hypertension IL1B IL1RN IL6 immune factor immune factors immune response IMPROVE individual Infection inhibitors Interaction involved KEGG KEGG pathway MBL2 NCBI NLRP3 non-immune nucleotides observé OMIM overlapping pathway Pathways performed personalised Polymorphisms Potential PPI Predictive Predictive value Prevent Prognosis protein-protein interaction provide RAAS receptor Result risk of infection SARS-CoV-2 serious COVID-19 severity signaling pathway signaling pathways susceptibility susceptibility gene TLR4 Treatment Vaccine Vaccine development Variation Viral viral infection Vitamin D with COVID-19 [DOI] 10.7150/ijms.67815 PMC 바로가기 [Article Type] Research Paper
The role of Mannose-binding lectin in leprosy: A systematic reviewarticle Published on 2021-09-302024-09-01 Journal: Infection, Genetics and Evolution [Category] 한센병, [키워드] complement system Innate immunity leprosy MBL2 polymorphism [Article Type] article
Why does SARS-CoV-2 hit in different ways? Host genetic factors can influence the acquisition or the course of COVID-19SARS-CoV-2가 다른 방식으로 공격하는 이유는 무엇입니까? 숙주 유전적 요인은 COVID-19의 획득 또는 경과에 영향을 미칠 수 있습니다Review Published on 2021-06-012022-09-11 Journal: European journal of medical genetics [Category] SARS, 바이오마커, 변종, 유전자 메커니즘, [키워드] acquisition Affect age association available data carried CD27 Comorbidities Course COVID-19 COVID-19 pandemic COVID19 cure Data mining death demonstrated distribution epidemiological epidemiological data Evidence evidence of Factor FIVE General population Genes genetic background genetic risk factor genetic risk factors Genetic variant Host Host genetic factor Infection inhibitor Innate immunity involved list list of gene MBL2 Mutation outcome polymorphism population distribution Population screening Prevalence protease Protein provide response SARS-CoV-2 SARS-COV-2 infection Serine serine 2 SNPs supported term text mining TMPRSS2 transmembrane variant [DOI] 10.1016/j.ejmg.2021.104227 PMC 바로가기 [Article Type] Review
Mannose binding lectin gene 2 (rs1800450) missense variant may contribute to development and severity of COVID-19 infectionResearch Paper Published on 2021-01-272023-06-16 Journal: Infection, genetics and evolution : journal of mol [Category] MERS, SARS, [키워드] COVID-19 cytokine gene mutation hyperinflammation MBL2 SARS-CoV-2 [DOI] 10.1016/j.meegid.2021.104717 PMC 바로가기 [Article Type] Research Paper
Glycomic analysis of host response reveals high mannose as a key mediator of influenza severityArticle Published on 2020-10-272023-06-14 Journal: Proceedings of the National Academy of Sciences of [Category] Fulltext, 신종인플루엔자, [키워드] lectin array lectin microarray mannan binding lectin mannose binding lectin MBL2 [DOI] 10.1073/pnas.2008203117 PMC 바로가기
Exploring association between MBL2 gene polymorphisms and the occurrence of clinical blackwater fever through a case–control study in Congolese childrenMBL2 유전자 다형성과 콩고 아동에서의 임상적 흑수병 발생 간의 연관성 탐색: 사례-대조 연구Research Published on 2020-01-152024-08-11 Journal: Malaria Journal [Category] 말라리아, [키워드] Blackwater fever Democratic Republic of Congo Mannose-Binding Lectin 2 MBL2 severe malaria [DOI] 10.1186/s12936-020-3100-8 PMC 바로가기 [Article Type] Research