Reliability and clinical correlations of semi-quantitative lung ultrasound on BLUE points in COVID-19 mechanically ventilated patients: The ‘BLUE-LUSS’-A feasibility clinical studyArticle Published on 2022-10-142022-11-16 Journal: PLoS ONE [Category] COVID19(2023년), SARS, 치료기술, [키워드] clinical study correlated correlation COVID-19 COVID-19 pandemic Critically ill Critically ill patient critically ill patients diagnostic feasibility ICUs independent indicated information intensive care intensive care unit Intervention lung Lung pathology mechanically ventilated P/F P/F ratio positive reduce Region reliability risk of infection RT-PCR SARS-CoV2 semi-quantitative significantly single-center the patient Treatment university Variability ventilated patient was performed were recorded [DOI] 10.1371/journal.pone.0276213 PMC 바로가기
Barotrauma in COVID 19: Incidence, pathophysiology, and effect on prognosisResearch article Published on 2022-10-012022-10-05 Journal: Clinical imaging [Category] 진단, [키워드] 95% CI barotrauma Chest radiography Cohort conducted coronavirus covariates COVID COVID-19 COVID-19 patients death determine emphysema incidence increase in increased risk intubated COVID-19 patient intubation IQR mechanical ventilation mechanically ventilated median time Mortality objective outcome pathophysiology Patient patient mortality patients died patients with COVID-19 performed Pneumomediastinum Pneumothorax Prognosis Result Retrospective study Risk factors secondary outcome the median [DOI] 10.1016/j.clinimag.2022.06.014 [Article Type] Research article
Patient-centered outcomes at hospital discharge in mechanically ventilated COVID-19 patients in Kobe, Japan: A single-center retrospective cohort studyResearch article Published on 2022-09-012022-10-05 Journal: Respiratory investigation [Category] 변종, [키워드] Activities of Daily Living adult COVID-19 patient clinical clinically Comorbidity conducted coronavirus disease COVID-19 COVID-19 infection COVID-19 patient Critical care demonstrated died discharge Dyspnea functional hospital discharge Hospitalization ICU in-hospital mortality independent intensive care interquartile range invasive Japan Kobe mechanical ventilation mechanically ventilated median age on mechanical ventilation organ dysfunction organ function outcome Patient receiving required Respiratory Support respiratory symptoms Result retrospective cohort study Retrospective study single-center survived survivor Survivors the patient was related [DOI] 10.1016/j.resinv.2022.06.010 [Article Type] Research article
Dysregulation of the kallikrein-kinin system in bronchoalveolar lavage fluid of patients with severe COVID-19Research article Published on 2022-08-052022-10-05 Journal: EBioMedicine [Category] SARS, 바이오마커, 유전자 메커니즘, 진단, 치료기술, [키워드] ACE2 acute respiratory syndrome angiotensin-converting enzyme 2 BAL BAL fluid bind Biomarker Bronchoalveolar lavage Bronchoalveolar lavage fluid Coagulation system complexes contribute coronavirus COVID COVID-19 Critical dysregulation explain extracellular traps finding funding help hydrolytic activity Hypothesis increased vascular permeability inflammatory chemokines kallikrein-kinin Kallikrein-kinin system Kallikreins Kinins Leuven mechanically ventilated mechanically ventilated patient median myeloperoxidase NETs Neutrophil extracellular trap observation occur oedema Patient patients without COVID-19 peptide peptides plasma potential treatment option receptor Research SARS-CoV-2 severe COVID-19 severe pulmonary disease Support thromboembolic complication thromboembolic complications Thromboinflammation tissue [DOI] 10.1016/j.ebiom.2022.104195 [Article Type] Research article
Aspergillus detection in airways of ICU COVID-19 patients: To treat or not to treat?ICU COVID-19 환자의 기도에서 아스페르길루스 검출: 치료할 것인가, 말 것인가?Case Reports Published on 2022-08-012022-09-11 Journal: Journal de mycologie médicale [Category] COVID19(2023년), SARS, 바이오마커, 치료기술, [키워드] absence airway Antifungal Antifungal treatment Antigen Aspergillus Aspergillus fumigatus Atypical COVID-19 Culture difficulty galactomannan highlight ICU ICU patient ICU Patients Intubated invasive Invasive pulmonary aspergillosis IPA management mechanically ventilated mechanically ventilated patient mechanically ventilated patients outcome Patient patients PCR Pneumonia pulmonary aspergillosis radiological Respiratory samples respiratory tract sample respiratory tract samples risk SARS CoV SARS CoV-2 SARS-CoV-2 SARS-CoV-2 pneumonia severe COVID-19 Symptomatology treat [DOI] 10.1016/j.mycmed.2022.101290 PMC 바로가기 [Article Type] Case Reports
Mortality of Mechanically Ventilated COVID-19 Patients in Traditional versus Expanded Intensive Care Units in New YorkMulticenter Study Published on 2022-08-012022-10-06 Journal: Annals of the American Thoracic Society [Category] 진단, [키워드] 95% CI 95% confidence interval cohort study coronavirus disease COVID COVID pandemic COVID-19 COVID-19 patient COVID-19 patients Critical care Critically ill Critically ill patient died discharged evaluate expanded ICU First wave greater hazard ratio health system hospital hospital occupancy for critically ill patients ICU ICUs in-hospital mortality increased mortality increased risk intensive care unit intubation mechanically ventilated mechanically ventilated COVID-19 patients mechanically ventilated patient Mortality New York New York City not different outcome pandemic Patient resulting retrospective risk surpassed survived Traditional traditional ICU. transferred with COVID-19 [DOI] 10.1513/AnnalsATS.202106-705OC PMC 바로가기 [Article Type] Multicenter Study
Mesenchymal stromal cell therapy for acute respiratory distress syndrome due to coronavirus disease 20192019년 코로나바이러스로 인한 급성호흡곤란증후군에 대한 중간엽 기질세포 치료Article Published on 2022-08-012022-09-12 Journal: Cytotherapy [Category] 진단, [키워드] 95% CI 95% confidence interval acute lung injury acute respiratory distress acute respiratory distress syndrome Allogeneic anti-inflammatory property ARDS C-reactive protein case sery cells clinical outcomes coronavirus disease COVID-19 COVID-19-associated ARDS declined discharged dose eligible follow-up period high mortality hospital Inflammatory cytokine intensive care Kidney injury less liver Lung disease mechanical ventilation mechanically ventilated median time Mesenchymal stromal cell Mesenchymal stromal cells moderate MSC MSCs nine Patient patients patients died remained Remestemcel-L requiring supplemental oxygen resulting Safe shown significantly stromal cell syndrome therapy treat treated were excluded [DOI] 10.1016/j.jcyt.2022.03.006 PMC 바로가기 [Article Type] Article
Intravenous IgM-enriched immunoglobulins in critical COVID-19: a multicentre propensity-weighted cohort study중요한 COVID-19에서 정맥내 IgM이 풍부한 면역글로불린: 다기관 성향 가중 코호트 연구Multicenter Study Published on 2022-07-072022-09-12 Journal: Critical Care [Category] COVID19(2023년), SARS, 진단, [키워드] 30-Day mortality acute respiratory distress addition applied Characteristics clinical clinically Cohort cohort study Complication concerning confidence interval controls coronavirus disease COVID-19 COVID-19 patients Cox regression models Critical Critically ill Critically ill patient daily dose dose early administration Effect Efficacy high mortality ICU ICU Patients Immunoglobulin immunoglobulin M immunoglobulins Inflammatory intravenous laboratory-confirmed Lung injury mechanical ventilation mechanically ventilated Mortality multicentre overcome Patient Primary outcome randomization randomized clinical trials retrospective SARS-CoV-2 selection bia statistical significance statistically statistically significant difference subgroup analysis subgroups survival treated Treatment treatment regimen two group was performed Weighting with COVID-19 [DOI] 10.1186/s13054-022-04059-0 PMC 바로가기 [Article Type] Multicenter Study
Cardiovascular subphenotypes in patients with COVID-19 pneumonitis whose lungs are mechanically ventilated: a single-centre retrospective observational studyObservational Study Published on 2022-07-012022-10-04 Journal: Anaesthesia [Category] 임상, [키워드] acute respiratory distress acute respiratory distress syndrome age aligned Analysis cardiovascular Clinical characteristics clinical outcomes cohort study conducted echocardiographic ICU patient impairment IQR Latent latent class lung male mechanically ventilated mechanism median moderate mortality rate mortality rates outcomes parameters pathophysiology Patient patients with COVID-19 performed preserved Prone ventilation retrospective right ventricular dysfunction right ventricular failure syndrome transthoracic echocardiography Treatment response Unsupervised clustering variable variables ventricular ventricular dysfunction with COVID-19 [DOI] 10.1111/anae.15700 PMC 바로가기 [Article Type] Observational Study
Predicting Impact of Prone Position on Oxygenation in Mechanically Ventilated Patients with COVID-19Observational Study Published on 2022-07-012022-10-04 Journal: Journal of Intensive Care Medicine [Category] Coronavirus, 임상, [키워드] acute respiratory distress ARDS average benefit concomitant use consecutive patient COVID-19 effective hypoxemic Impact improvements in oxygenation improving oxygenation individual Inhaled instances IQR mechanical ventilation mechanically ventilated mechanically ventilated patient median Oxygenation PaO paO2/fiO2 Patient patients with COVID-19 position predict Primary outcome prone prone positioning proning Respiratory failure retrospective Supine position sustained syndrome Tertiary tertiary care center the median the patient variable ventilator with COVID-19 [DOI] 10.1177/08850666221081757 PMC 바로가기 [Article Type] Observational Study