Modified polysulfone membrane facilitates rapid separation of plasma from whole blood for an effective anti-SARS-CoV-2-IgM diagnosisarticle Published on 2023-08-222024-09-05 Journal: Burma Med J [Category] update2024, [키워드] Biochemistry chemical modification Enzyme mechanisms Immunochemistry membranes Polymer chemistry [DOI] 10.1038/s41598-023-40871-6 PMC 바로가기 [Article Type] article
Subtle vascular and astrocytic changes in the brain of coronavirus disease 2019 (COVID-19) patientsArticle Published on 2022-12-012022-11-15 Journal: European journal of neurology [Category] COVID19(2023년), SARS, 진단, [키워드] Activation acute respiratory syndrome analysed Analysis AQP4 aquaporin 4 Astrocyte astrocytes Blood Brain brain blood vessels calculated CD31 Central nervous system change changes changes in co-expression collagen control patient controls coronavirus coronavirus disease COVID-19 COVID-19 cases COVID-19 patients decrease described endothelial fluorescent Fractal dimension GFAp immunohistochemistry Infection inflammatory signalling light microscopy lymphocyte membrane membranes microglial morphological change morphology Patient patients perivascular Protein reduced reduction SARS-CoV-2 SARS-COV-2 infection significantly increased Vascular vascular basement membranes. vessel [DOI] 10.1111/ene.15545 PMC 바로가기
Antioxidant, Anti-inflammatory, and Immunomodulatory Roles of Nonvitamin Antioxidants in Anti-SARS-CoV-2 TherapyArticle Published on 2022-10-132022-11-15 Journal: Journal of medicinal chemistry [Category] COVID19(2023년), SARS, 바이오마커, 치료제, [키워드] ACE2 receptor Activation activities alleviate Alleviating alveolar antioxidant antiviral role conformational change COVID-19 Cytokine storm Dipeptidyl peptidase 4 Direct dosage Endothelium favor furin Helicase host receptor hyperinflammation Illness severity immunogenic Inflammatory Inflammatory responses influences membranes Organ failure oxidative stress Papain-like protease pathology pathway protease reactive oxygen specy Receptor binding domain Replication risk RNA-dependent RNA polymerase role serine 2 the spike protein transmembrane vicious cycle viral spike protein [DOI] 10.1021/acs.jmedchem.2c01134 PMC 바로가기
Expanding the antiviral potential of the mosquito lipid-transfer protein AEG12 against SARS-CoV-2 using hydrophobic antiviral ligandsArticle Published on 2022-10-012022-11-15 Journal: Febs Letters [Category] COVID19(2023년), SARS, 치료제, [키워드] Antiviral antiviral activity antiviral therapeutics bind Cell complexes Compound cytotoxicity drug delivery enveloped virus fatty Fatty acid hydrophobic inhibitors Ligand ligands lipid-binding protein mechanism membrane membrane disruption. membranes modulated neutralize Protein replaced resulting SARS-CoV-2 Therapeutic compounds unsaturated viruses [DOI] 10.1002/1873-3468.14456 PMC 바로가기
Biophysical Modeling of SARS-CoV-2 Assembly: Genome Condensation and BuddingArticle Published on 2022-09-202022-11-16 Journal: Viruses [Category] SARS, 유전자 메커니즘, [키워드] assembly budding caused cellular condensation coronavirus 2 COVID-19 pandemic curtail de novo develop drug target envelope Genome genome condensation genomic RNA host cell identify Infectious virus Interaction intrinsic M protein mechanism membranes modeling molecular Mutation N protein oligomerization pathogen Protein protein intrinsic curvature. Research respiratory responsible resulting RNA SARS-CoV-2 spike structural protein structural proteins the S protein therapeutic target therapy Vaccines viral entry viral life cycle viral particle virus while [DOI] 10.3390/v14102089 PMC 바로가기
Development of passive samplers for the detection of SARS-CoV-2 in sewage and seawater: Application for the monitoring of sewage하수 및 해수 내 SARS-CoV-2 검출을 위한 패시브 샘플러 개발: 하수 모니터링을 위한 응용Article Published on 2022-08-102022-09-11 Journal: The Science of the total environment [Category] COVID19(2023년), SARS, 치료기술, 치료제, [키워드] application both virus both viruses collected Concentration conducted coronavirus correlated determine development diarrhea epidemic diarrhea Epidemiology Evolution Frequency Genome immersion inactivated increase in influent membrane membranes no significant difference Norovirus Nylon Passive Passive samplers PEDV Polymer public health recent SARS-CoV-2 SARS-CoV-2 detection SARS-CoV-2 genome Seawater sewage shown significant difference significantly higher the SARS-CoV-2 Treatment virus virus detection viruses wastewater Wastewater- seawater. water [DOI] 10.1016/j.scitotenv.2022.155139 PMC 바로가기 [Article Type] Article
Bomidin: An Optimized Antimicrobial Peptide With Broad Antiviral Activity Against Enveloped VirusesBomidin: 외피 바이러스에 대한 광범위한 항바이러스 활성을 가진 최적화된 항균 펩티드Article Published on 2022-05-192022-09-11 Journal: Frontiers in Immunology [Category] COVID19(2023년), SARS, 치료제, [키워드] activity acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus-2 Against AMP AMPs antibiotic antimicrobial antimicrobial peptide antimicrobial peptide. antimicrobial peptides AVP Bacteria Bacterial bovine Chikungunya Chikungunya virus CHIKV Coronavirus-2 Defense Dengue dengue virus DENV-2 disrupt Escherichia coli Evolution expressed expression extraction front line fungi global public health herpes simplex herpes simplex virus heterologous expression HSV-2 life-threatening lipids mechanism membrane membranes methionine molecular offer organism overcome pathogen Pathogens peptide peptides produced purification Research SARS-CoV-2 sequence Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus therapeutic variety virus viruses [DOI] 10.3389/fimmu.2022.851642 PMC 바로가기 [Article Type] Article
Ultrastructural insight into SARS-CoV-2 entry and budding in human airway epithelium사람의 기도 상피에서 SARS-CoV-2 진입 및 발아에 대한 미세구조적 통찰력Article Published on 2022-03-252022-09-11 Journal: Nature Communications [Category] MERS, SARS, 변종, 진단, 치료법, [키워드] ACE2 airway epithelium B.1.1.7 B.1.1.7 variant budding cilia ciliary ciliated ciliated cell ciliated cells Concentration direct fusion envelope epithelial cells examined excluded explain Extracellular Genome goblet host cells Human airway epithelium Intact isolate isolates mechanism membrane membranes microvilli nucleocapsid nucleocapsids periphery plasma membrane profile profiles S glycoprotein SARS-CoV-2 SARS-CoV-2 entry SARS-CoV-2 infected cell SARS-CoV-2 infected cells TMPRSS2 tomography transmission electron microscopy Viral viral entry viral membrane virion virions virus [DOI] 10.1038/s41467-022-29255-y PMC 바로가기 [Article Type] Article
Erythro-VLPs: Anchoring SARS-CoV-2 spike proteins in erythrocyte liposomesErythro-VLPS : 적혈구 리포좀에서 SARS-COV-2 스파이크 단백질을 고정시킨다Research Article Published on 2022-03-112022-09-10 Journal: PLoS ONE [Category] MERS, SARS, 변종, [키워드] ACE-2 acute respiratory syndrome acute respiratory syndrome coronavirus 2 Administered anchoring angiotensin angiotensin converting enzyme angiotensin converting enzyme 2 assays average binding BLI Blood blood cell Cell coronavirus coronavirus disease COVID-19 cytoplasmic membrane defined dose-dependent Dynamics ELISA enzyme enzyme-linked immunosorbent assay enzyme-linked immunosorbent assays facilitate fluorescent functional insertion intravenously Liposome membranes molecular dynamics novel open outer membrane pandemic Particles platform Protein protocol red blood cell respiratory S-protein SARS-CoV-2 spike SARS-CoV-2 spike protein scattering Seroconversion severe acute respiratory syndrome Coronavirus surfactant the SARS-CoV-2 therapeutic strategy Therapeutics Trial variants virus viruses was used [DOI] 10.1371/journal.pone.0263671 PMC 바로가기 [Article Type] Research Article
[Review of new evidence about the possible vertical transmission of coronavirus disease-2019][코로나바이러스 질병-2019의 수직적 전파 가능성에 대한 새로운 증거 검토]Review Published on 2022-03-012022-09-11 Journal: Gaceta sanitaria [Category] SARS, 치료기술, [키워드] amniotic Amniotic fluid Blood can not Clinical diagnosis clinical sample clinical samples clinically conjunction Contamination Cord blood coronavirus COVID-19 criteria diagnosis of COVID-19 English Evidence guide Health Organization human milk indican infective Isolation management maternal blood membranes nine para patients with COVID-19 peer-reviewed Placenta Placentas positive Protein required RNA SARS-CoV-2 SARS-CoV-2 RNA Sin Spanish systematic review Transmisión vertical Transmission umbilical Umbilical cord umbilical cord blood vertical transmission Viral particles women World Health Organization [DOI] 10.1016/j.gaceta.2020.06.005 PMC 바로가기 [Article Type] Review