Delivery of Antibody-Like Molecules, Monobodies, Capable of Binding with SARS-CoV-2 Virus Nucleocapsid Protein, into Target CellsArticle Published on 2022-10-012022-11-15 Journal: Doklady. Biochemistry and biophysics [Category] COVID19(2023년), SARS, 진단, [키워드] antibody-like molecules C-terminus cellular cellular thermal shift assay delivery demonstrated E. coli expressed fluorescent fused HEK293T cell highest affinity Interaction molecules monobody nucleocapsid nucleocapsid protein penetration peptide Previous studies produced Protein replacement resulting S10 shuttle peptide SARS-CoV-2 selected significantly target target cells TAT TAT peptide the SARS-CoV-2 thermophoresis transfected with [DOI] 10.1134/S1607672922050088 PMC 바로가기
Among Antibody-Like Molecules, Monobodies, Able to Interact with Nucleocapsid Protein of SARS-CoV Virus, There Are Monobodies with High Affinity to Nucleocapsid Protein of SARS-CoV-2 Virus항체 유사 분자 중 SARS-CoV 바이러스의 뉴클레오캡시드 단백질과 상호작용할 수 있는 모노바디 중 SARS-CoV-2 바이러스의 뉴클레오캡시드 단백질과 친화도가 높은 모노바디가 있음Article Published on 2022-04-012022-09-11 Journal: Doklady. Biochemistry and biophysics [Category] COVID19(2023년), SARS, 진단, 치료법, [키워드] affinity affinity binding Amino acid amino acid sequence Amino acid sequences antibody antibody-like molecules dissociation Dissociation constant E. coli high affinity molecules monobody Ni-NTA nucleocapsid nucleocapsid protein nucleotide SARS-CoV SARS-CoV virus SARS-CoV-2 SARS-CoV-2 virus selected sequence Seven shown the SARS-CoV-2 virus thermophoresis were expressed [DOI] 10.1134/S1607672922020077 PMC 바로가기 [Article Type] Article