CD169-mediated restrictive SARS-CoV-2 infection of macrophages induces pro-inflammatory responses
Article
[키워드] ACE2
activated
Activation
alleviate
Antigen
CD169
CD169+ macrophage
contribute
COVID-19 pathology
COVID-19 patients
de novo
elicited
exogenous ACE2
expression
expression of SARS-CoV-2
facilitated
genomic
humans
Hyperinflammatory
IL-1β
IL-6
independent
induce
Infection
innate immune response
Macrophage
macrophages
MDA-5
monocyte
myeloid cell
Post-mortem
primary target cell
pro-inflammatory cytokine
pro-inflammatory response
Remdesivir
Replication
Restricted
RIG-I
RNA
SARS-CoV-2
SARS-CoV-2 entry
SARS-COV-2 infection
subgenomic RNA
subsequent
suppressed
the SARS-CoV-2
thought
TNFα
Treatment
viral particle
Viral protein
Viral RNA
[DOI] 10.1371/journal.ppat.1010479 PMC 바로가기
[DOI] 10.1371/journal.ppat.1010479 PMC 바로가기