Evaluation of Two Broadly Used Commercial Methods for Detection of Respiratory Viruses with a Recently Added New Target for Detection of SARS-CoV-2SARS-CoV-2 검출을 위해 최근에 추가된 새로운 표적으로 호흡기 바이러스 검출을 위해 널리 사용되는 두 가지 상용 방법 평가Article Published on 2022-07-132022-09-11 Journal: Viruses [Category] COVID19(2023년), SARS, 치료기술, 치료제, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 agreement ARI AusDiagnostics AusDiagnostics assay automated caused clinical symptom Clinical symptoms coronavirus COVID-19 COVID-19 patient COVID-19 patients detect detection Essential Inc. Mascot medium molecular Molecular assay New nonspecific option other respiratory virus Other respiratory viruses reference method respiratory respiratory tract infection respiratory virus respiratory viruses SARS-CoV-2 Seven severe acute respiratory syndrome Coronavirus specificity target validation [DOI] 10.3390/v14071530 PMC 바로가기 [Article Type] Article
In Silico Molecular Dynamics of Griseofulvin and Its Derivatives Revealed Potential Therapeutic Applications for COVID-19Griseofulvin 및 그 파생물의 In Silico 분자 역학, COVID-19에 대한 잠재적인 치료 응용 프로그램 공개Article Published on 2022-06-212022-09-11 Journal: International Journal of Molecular Sciences [Category] COVID19(2023년), SARS, 신약개발, 치료제, [키워드] ACE2 Analysis angiotensin angiotensin-converting enzyme 2 anti-SARS-CoV-2 application approved drug approved drugs Computational approaches coronavirus disease Coronavirus disease 2019 COVID-19 derivative docking docking score domain Drug repurposing Dynamics Efficacy examined followed by future therapeutic griseofulvin griseofulvin derivatives highest human host hydrogen hydrogen bonds inhibitor inhibitory molecular molecular docking analysis molecular dynamics option Potential protease RBD RdRP Revealed SARS-CoV-2 SARS-COV-2 infection Spike protein Therapeutic approach therapeutic approaches [DOI] 10.3390/ijms23136889 PMC 바로가기 [Article Type] Article
Characterization of SARS-CoV-2 Evasion: Interferon Pathway and Therapeutic OptionsSARS-CoV-2 회피의 특성화: 인터페론 경로 및 치료 옵션Review Published on 2022-06-082022-09-11 Journal: Viruses [Category] COVID19(2023년), SARS, 변종, 유전자 메커니즘, 치료제, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus antagonism Antiviral antiviral therapy characterization characterized circumvent contribute Control Coronavirus-2 COVID-19 COVID-19 pandemic COVID-19 patients Critical critical state drug dysregulated Efficacy evade explain expression Factor helping host innate immunity IFN IFN response IFN signaling pathway IFN-III IFNs in some individual Infection inhibit innate immune innate immune response Innate immunity interferon interferon-stimulated gene ISG mechanism new SARS-CoV-2 option pathogenicity Pathways pro-inflammatory cytokine responsible robust SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 pathogenesis Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus-2 the disease therapy treat Vaccines variant virus virus–host interactions [DOI] 10.3390/v14061247 PMC 바로가기 [Article Type] Review
Efficient and Sustainable Platform for Preparation of a High-Quality Immunoglobulin G as an Urgent Treatment Option During Emerging Virus Outbreaks신종 바이러스 발생 시 긴급 치료 옵션으로 고품질 면역글로불린 G를 준비하기 위한 효율적이고 지속 가능한 플랫폼Article Published on 2022-05-172022-09-12 Journal: Frontiers in Immunology [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] Affect affected analyzed anti-SARS-CoV-2 approach average caprylic acid caprylic acid precipitation Concentration convalescent plasma convalescent plasma processing correlated COVID-19 COVID-19 pandemic demonstrated donors downstream Effectiveness Efficacy efficient Epidemic Final fraction IgA IgG IgG subclass IgM immunization Immunoglobulin Immunoglobulin G Infectious disease ion-exchange chromatography mass spectrometry Neutralization assay neutralization potency neutralize Neutralizing antibodies offer option outbreak overcome pandemic status Passive immunotherapy plasma polyclonal polyclonal anti-COVID-19 IgG preparation proportion provided purification Quality control reducing reduction remained significantly therapeutic transfusion reactions Treatment viral outbreak wild-type SARS-CoV-2 wild-type SARS-CoV-2 neutralization assay. [DOI] 10.3389/fimmu.2022.889736 PMC 바로가기 [Article Type] Article
Is Telerehabilitation a Viable Option for People With Low Back Pain? Associations Between Telerehabilitation and Outcomes During the COVID-19 PandemicObservational Study Published on 2022-05-052022-10-05 Journal: Physical therapy [Category] 임상, [키워드] 95% CI age association back back pain Care clinics COVID-19 effective Effectiveness episode Frequency functional individual involved low back pain majority no significant difference option outcome outcomes Patient satisfaction physical Physical therapy positive Probability Propensity score proportion receiving rehabilitation reported representing Satisfaction significantly synchronous telerehabilitation therapy Treatment Viable was used were used [DOI] 10.1093/ptj/pzac020 PMC 바로가기 [Article Type] Observational Study
Evaluating the in vitro efficacy of bovine lactoferrin products against SARS-CoV-2 variants of concern우려되는 SARS-CoV-2 변이체에 대한 소 락토페린 제품의 시험관 내 효능 평가Article Published on 2022-04-012022-09-11 Journal: Journal of dairy science [Category] COVID19(2023년), SARS, 변종, 신약개발, [키워드] African Analysis anti-SARS-CoV-2 Anti-SARS-CoV-2 Activity B.1.1.7 B.1.1.7 variant B.1.351 bovine cell line Characteristics Clinical significance conjunction Delta dextrose digestion Efficacy Entry mechanism entry mechanisms Evaluating glycoprotein half-maximal inhibitory concentration high-content imaging human clinical trials human lung immunomodulatory in vitro ingredient inhibit inhibited inhibitory concentration lactoferrin mechanisms microbes milk option P.1 Pathogens pepsin Protein released SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 treatment SARS-CoV-2 variant SARS-CoV-2 variants sorbitol South Tablet Treatment variants variants of concern viral strain viruses [DOI] 10.3168/jds.2021-21247 PMC 바로가기 [Article Type] Article
Need for More Randomized Controlled Trials With Rigorous Methodology to Confirm That Ivermectin Is Not a Viable Option for the Treatment of Coronavirus Disease 2019Ivermectin이 코로나바이러스 질병 2019의 치료를 위한 실행 가능한 옵션이 아님을 확인하기 위해 엄격한 방법론을 사용하는 더 많은 무작위 대조 시험의 필요성Article Published on 2022-03-232022-09-11 Journal: Clinical Infectious Diseases: An Official Publicat [Category] SARS, 임상, [키워드] Controlled option Viable [DOI] 10.1093/cid/ciab689 PMC 바로가기 [Article Type] Article
An Upgrade on the Surveillance System of SARS-CoV-2: Deployment of New Methods for Genetic InspectionSARS-CoV-2의 감시 시스템 업그레이드: 유전자 검사를 위한 새로운 방법 배포Article Published on 2022-03-152022-09-11 Journal: International Journal of Molecular Sciences [Category] SARS, 변종, 치료기술, [키워드] Abnormal result Analysis analyzed consensus sequence country delta variant dominant equipment faster Genetic genetic surveillance information Inspection lack Mutation mutations New next generation sequencing NGS option Population positive qPCR qPCR variant screening. reported RT-qPCR SARS-CoV-2 SARS-CoV-2 epidemiology SARS-CoV-2 sequence SARS-CoV-2 sequences SARS-CoV-2 surveillance SARS-CoV-2 variant SARS-CoV-2 variant identification screening test sequenced Surveillance System Upgrade variant variants [DOI] 10.3390/ijms23063143 PMC 바로가기 [Article Type] Article
Heterotopic Ossification in Post-COVID-19 Patient on Anticoagulation with Limited Treatment OptionsConference abstract Published on 2022-03-012022-10-05 Journal: Archives of physical medicine and rehabilitation [Category] 치료법, [키워드] abdomen Abnormalities Admission anticoagulation approach avoidance Bilateral bisphosphonate Coagulation COVID-19 COVID-19 patient demonstrated diabetes Diagnosis Dyspnea endocrinology event Factors GRADE grade 3 Heterotopic ossification high risk Hospitalization hypertension ICU Intubated intubation Limited male measure nonsteroidal anti-inflammatory drug objective option Orthopedics Pain PAIN MANAGEMENT participant past medical history Pharmacy provided rehabilitation Result setting therapy Treatment unique unit university was done weakness while worsening [DOI] 10.1016/j.apmr.2022.01.094 [Article Type] Conference abstract
Human Papillomavirus Self-Sampling for Primary Cervical Cancer Screening in Under-Screened Women in Hong Kong during the COVID-19 PandemicCOVID-19 팬데믹 기간 동안 홍콩에서 과소 선별된 여성의 1차 자궁경부암 검진을 위한 인유두종바이러스 자가 샘플링Article Published on 2022-02-242022-09-10 Journal: International Journal of Environmental Research an [Category] COVID19(2023년), MERS, SARS, 치료기술, [키워드] 95% CI Arm best Cancer Cancer screening Cervical cervical cancer cervical cancer screening Cohen’s kappa Concordance confidence interval COVID-19 COVID-19 pandemic effective Effectiveness focus Hong Kong HPV Human human papillomavirus (HPV) media option papillomavirus Participation population groups recruited response rate returned Screening Self-sampling social media specimen uptake rate women [DOI] 10.3390/ijerph19052610 PMC 바로가기 [Article Type] Article